2KETO-3METHYLVALERATE-RXN

Reaction 2KETO-3METHYLVALERATE-RXN

• direction:
  • REVERSIBLE
• common name:
  • (S)-3-methyl-2-oxopentanoate dehydrogenase (acylating)
• ec number:
  • EC-1.2.1
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 2-KETO-3-METHYL-VALERATE[c] + 1 CO-A[c] <=> 1 2-METHYL-BUTYRYL-COA[c] + 1 NADH[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 NAD+[c] + 1 (S)-3-methyl-2-oxopentanoate[c] + 1 coenzyme A[c] <=> 1 2-methylbutanoyl-CoA[c] + 1 NADH[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_3260
  • Source: orthology-creinhardtii
• Gene: Tiso_gene_18084
  • Source: orthology-creinhardtii
• Gene: Tiso_gene_11793
  • Source: orthology-creinhardtii

Pathways

• PWY-5108, L-isoleucine biosynthesis V: PWY-5108
  • 2 reactions found over 3 reactions in the full pathway
• ILEUDEG-PWY, L-isoleucine degradation I: ILEUDEG-PWY
  • 4 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-creinhardtii
    • Tool: pantograph

External links

• RHEA:
  • 30907
• LIGAND-RXN:
  • R03171