BRANCHED-CHAINAMINOTRANSFERILEU-RXN

Reaction BRANCHED-CHAINAMINOTRANSFERILEU-RXN

• direction:
  • REVERSIBLE
• common name:
  • branched-chain_amino_acid_aminotransferase
• ec number:
  • EC-2.6.1.42
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 ILE[c] + 1 2-KETOGLUTARATE[c] <=> 1 GLT[c] + 1 2-KETO-3-METHYL-VALERATE[c]
• With common name(s):
  • 1 L-isoleucine[c] + 1 2-oxoglutarate[c] <=> 1 L-glutamate[c] + 1 (S)-3-methyl-2-oxopentanoate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_14984
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: annotation-experimental_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-athaliana
  • Source: orthology-synechocystis
  • Source: orthology-esiliculosus
  • Source: orthology-creinhardtii
• Gene: Tiso_gene_18403
  • Source: orthology-synechocystis
• Gene: Tiso_gene_17748
  • Source: orthology-athaliana
  • Source: orthology-esiliculosus

Pathways

• ILEUSYN-PWY, L-isoleucine biosynthesis I (from threonine): ILEUSYN-PWY
  • 7 reactions found over 7 reactions in the full pathway
• ILEUDEG-PWY, L-isoleucine degradation I: ILEUDEG-PWY
  • 4 reactions found over 6 reactions in the full pathway
• PWY-5108, L-isoleucine biosynthesis V: PWY-5108
  • 2 reactions found over 3 reactions in the full pathway
• PWY-5103, L-isoleucine biosynthesis III: PWY-5103
  • 4 reactions found over 7 reactions in the full pathway
• PWY-5101, L-isoleucine biosynthesis II: PWY-5101
  • 5 reactions found over 8 reactions in the full pathway
• PWY-5078, L-isoleucine degradation II: PWY-5078
  • 2 reactions found over 3 reactions in the full pathway
• PWY-5104, L-isoleucine biosynthesis IV: PWY-5104
  • 3 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-athaliana
    • Tool: pantograph
  • Source: orthology-creinhardtii
    • Tool: pantograph
  • Source: orthology-synechocystis
    • Tool: pantograph
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: manual
  • Source: manual-primary_network
• Category: annotation
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 24801
• LIGAND-RXN:
  • R02199
• UNIPROT:
  • Q9PIM6
  • P38891
  • P47176
  • O86505
  • O14370
  • O32954
  • P0AB80