Difference between revisions of "3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CHORISMATE CHORISMATE] == * smiles: ** C=C(C(=O)[O-])OC1(C(O)C=CC(C([O-])=O)=C1) * common name:...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN 3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN] == * direction: ** L...")
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CHORISMATE CHORISMATE] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN 3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN] ==
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* smiles:
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* direction:
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** C=C(C(=O)[O-])OC1(C(O)C=CC(C([O-])=O)=C1)
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** LEFT-TO-RIGHT
 
* common name:
 
* common name:
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** chorismate
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** 3-hydroxyisobutyrate_mitochondrial
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* inchi key:
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** 3-hydroxyisobutyrate_dehydrogenase
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** InChIKey=WTFXTQVDAKGDEY-HTQZYQBOSA-L
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** uncharacterized_oxidoreductase
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* molecular weight:
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* ec number:
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** 224.17   
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** [http://enzyme.expasy.org/EC/1.1.1.31 EC-1.1.1.31]
 
* Synonym(s):
 
* Synonym(s):
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** chorismic acid
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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== Reaction(s) known to produce the compound ==
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* With identifiers:
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* [[CHORISMATE-SYNTHASE-RXN]]
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** 1 [[NAD]][c] '''+''' 1 [[CPD-12175]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[CH3-MALONATE-S-ALD]][c] '''+''' 1 [[NADH]][c]
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== Reaction(s) of unknown directionality ==
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* With common name(s):
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* [[PABASYN-RXN]]
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** 1 NAD+[c] '''+''' 1 (S)-3-hydroxy-isobutanoate[c] '''=>''' 1 H+[c] '''+''' 1 (S)-methylmalonate-semialdehyde[c] '''+''' 1 NADH[c]
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* [[CHORISMATEMUT-RXN]]
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* [[ISOCHORSYN-RXN]]
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== Genes associated with this reaction  ==
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* [[ANTHRANSYN-RXN]]
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Tiso_gene_7107]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: AUTOMATED-NAME-MATCH
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* Gene: [[Tiso_gene_19772]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
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** Source: [[annotation-experimental_annotation]]
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*** Assignment: EC-NUMBER
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* Gene: [[Tiso_gene_5857]]
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** Source: [[orthology-athaliana]]
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** Source: [[orthology-creinhardtii]]
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* Gene: [[Tiso_gene_19592]]
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** Source: [[orthology-esiliculosus]]
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** Source: [[orthology-creinhardtii]]
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* Gene: [[Tiso_gene_19590]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
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** Source: [[orthology-esiliculosus]]
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** Source: [[orthology-creinhardtii]]
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* Gene: [[Tiso_gene_19771]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: EC-NUMBER
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== Pathways  ==
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* [[VALDEG-PWY]], L-valine degradation I: [http://metacyc.org/META/NEW-IMAGE?object=VALDEG-PWY VALDEG-PWY]
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** '''8''' reactions found over '''8''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[orthology]]
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** Source: [[orthology-athaliana]]
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*** Tool: [[pantograph]]
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** Source: [[orthology-creinhardtii]]
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*** Tool: [[pantograph]]
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** Source: [[orthology-esiliculosus]]
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*** Tool: [[pantograph]]
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* Category: [[annotation]]
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** Source: [[annotation-experimental_annotation]]
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*** Tool: [[pathwaytools]]
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** Source: [[annotation-in-silico_annotation]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* CAS : 55508-12-8
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* LIGAND-RXN:
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* PUBCHEM:
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** [http://www.genome.jp/dbget-bin/www_bget?R02047 R02047]
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5460312 5460312]
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* UNIPROT:
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* HMDB : HMDB12199
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** [http://www.uniprot.org/uniprot/P29266 P29266]
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* LIGAND-CPD:
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** [http://www.uniprot.org/uniprot/P28811 P28811]
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** [http://www.genome.jp/dbget-bin/www_bget?C00251 C00251]
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** [http://www.uniprot.org/uniprot/Q8XAE4 Q8XAE4]
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* CHEMSPIDER:
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** [http://www.uniprot.org/uniprot/Q55702 Q55702]
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** [http://www.chemspider.com/Chemical-Structure.4573889.html 4573889]
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** [http://www.uniprot.org/uniprot/Q9XTI0 Q9XTI0]
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* CHEBI:
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{{#set: direction=LEFT-TO-RIGHT}}
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=29748 29748]
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{{#set: common name=3-hydroxyisobutyrate_mitochondrial}}
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* BIGG : chor
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{{#set: common name=3-hydroxyisobutyrate_dehydrogenase}}
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{{#set: smiles=C=C(C(=O)[O-])OC1(C(O)C=CC(C([O-])=O)=C1)}}
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{{#set: common name=uncharacterized_oxidoreductase}}
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{{#set: common name=chorismate}}
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{{#set: ec number=EC-1.1.1.31}}
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{{#set: inchi key=InChIKey=WTFXTQVDAKGDEY-HTQZYQBOSA-L}}
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{{#set: gene associated=Tiso_gene_7107|Tiso_gene_19772|Tiso_gene_5857|Tiso_gene_19592|Tiso_gene_19590|Tiso_gene_19771}}
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{{#set: molecular weight=224.17    }}
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{{#set: in pathway=VALDEG-PWY}}
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{{#set: common name=chorismic acid}}
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{{#set: reconstruction category=orthology|annotation}}
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{{#set: produced by=CHORISMATE-SYNTHASE-RXN}}
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{{#set: reconstruction source=orthology-creinhardtii|orthology-athaliana|annotation-in-silico_annotation|orthology-esiliculosus|annotation-experimental_annotation}}
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{{#set: reversible reaction associated=PABASYN-RXN|CHORISMATEMUT-RXN|ISOCHORSYN-RXN|ANTHRANSYN-RXN}}
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{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 21:22, 21 March 2018

Reaction 3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • 3-hydroxyisobutyrate_mitochondrial
    • 3-hydroxyisobutyrate_dehydrogenase
    • uncharacterized_oxidoreductase
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 NAD+[c] + 1 (S)-3-hydroxy-isobutanoate[c] => 1 H+[c] + 1 (S)-methylmalonate-semialdehyde[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • VALDEG-PWY, L-valine degradation I: VALDEG-PWY
    • 8 reactions found over 8 reactions in the full pathway

Reconstruction information

External links






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