Difference between revisions of "HOMOCYSMET-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=MET MET] == * smiles: ** CSCCC([N+])C([O-])=O * inchi key: ** InChIKey=FFEARJCKVFRZRR-BYPYZUCNS...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=HOMOCYSMET-RXN HOMOCYSMET-RXN] == * direction: ** REVERSIBLE * ec number: ** [http://enzyme.expasy....")
 
(2 intermediate revisions by the same user not shown)
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[[Category:Metabolite]]
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[[Category:Reaction]]
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=MET MET] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=HOMOCYSMET-RXN HOMOCYSMET-RXN] ==
* smiles:
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* direction:
** CSCCC([N+])C([O-])=O
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** REVERSIBLE
* inchi key:
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* ec number:
** InChIKey=FFEARJCKVFRZRR-BYPYZUCNSA-N
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** [http://enzyme.expasy.org/EC/2.1.1.14 EC-2.1.1.14]
* common name:
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** L-methionine
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* molecular weight:
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** 149.207   
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* Synonym(s):
 
* Synonym(s):
** M
 
** met
 
** methionine
 
** L-met
 
  
== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
* [[RXN-16165]]
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* With identifiers:
* [[RXN0-6948]]
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** 1 [[CPD-1302]][c] '''+''' 1 [[HOMO-CYS]][c] '''<=>''' 1 [[MET]][c] '''+''' 1 [[CPD-1301]][c]
* [[S-ADENMETSYN-RXN]]
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* With common name(s):
* [[RME144]]
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** 1 N5-methyl--tetrahydropteroyl tri-L-glutamate[c] '''+''' 1 L-homocysteine[c] '''<=>''' 1 L-methionine[c] '''+''' 1 tetrahydropteroyl tri-L-glutamate[c]
* [[METHIONINE--TRNA-LIGASE-RXN]]
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== Reaction(s) known to produce the compound ==
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== Genes associated with this reaction  ==
* [[RXN0-5063]]
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Genes have been associated with this reaction based on different elements listed below.
* [[R00946]]
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* Gene: [[Tiso_gene_1602]]
* [[RXN-8340]]
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** Source: [[annotation-experimental_annotation]]
* [[3.4.11.18-RXN]]
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*** Assignment: AUTOMATED-NAME-MATCH
* [[HOMOCYSTEINE-S-METHYLTRANSFERASE-RXN]]
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== Pathways  ==
* [[RXN0-949]]
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* [[PWY-702]], L-methionine biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-702 PWY-702]
* [[2.8.1.6-RXN]]
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** '''5''' reactions found over '''6''' reactions in the full pathway
* [[RXN-14950]]
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* [[PWY-5041]], S-adenosyl-L-methionine cycle II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5041 PWY-5041]
* [[RXN-14957]]
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** '''4''' reactions found over '''4''' reactions in the full pathway
* [[RXN-14959]]
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* [[PWY-6151]], S-adenosyl-L-methionine cycle I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6151 PWY-6151]
* [[HEMN-RXN]]
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** '''4''' reactions found over '''6''' reactions in the full pathway
* [[HOMOCYSMETB12-RXN]]
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* [[HSERMETANA-PWY]], L-methionine biosynthesis III: [http://metacyc.org/META/NEW-IMAGE?object=HSERMETANA-PWY HSERMETANA-PWY]
* [[1.8.4.14-RXN]]
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** '''3''' reactions found over '''4''' reactions in the full pathway
* [[RXN-17473]]
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* [[HOMOSER-METSYN-PWY]], L-methionine biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=HOMOSER-METSYN-PWY HOMOSER-METSYN-PWY]
* [[RXN-17472]]
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** '''4''' reactions found over '''5''' reactions in the full pathway
* [[MMUM-RXN]]
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== Reconstruction information  ==
* [[RXN0-1342]]
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* Category: [[annotation]]
* [[FORMYLMETHIONINE-DEFORMYLASE-RXN]]
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** Source: [[annotation-experimental_annotation]]
* [[RXN-17878]]
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*** Tool: [[pathwaytools]]
* [[RXN-17873]]
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** Source: [[annotation-in-silico_annotation]]
* [[RXN-17877]]
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*** Tool: [[pathwaytools]]
* [[RXN-17876]]
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* [[RXN-17875]]
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* [[RXN-17874]]
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* [[RXN-14480]]
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== Reaction(s) of unknown directionality ==
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* [[HOMOCYSMET-RXN]]
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== External links  ==
 
== External links  ==
* CAS : 63-68-3
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* RHEA:
* METABOLIGHTS : MTBLC57844
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21196 21196]
* PUBCHEM:
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* LIGAND-RXN:
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=6992087 6992087]
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** [http://www.genome.jp/dbget-bin/www_bget?R04405 R04405]
* HMDB : HMDB00696
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* UNIPROT:
* LIGAND-CPD:
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** [http://www.uniprot.org/uniprot/P25665 P25665]
** [http://www.genome.jp/dbget-bin/www_bget?C00073 C00073]
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** [http://www.uniprot.org/uniprot/P45331 P45331]
* CHEBI:
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** [http://www.uniprot.org/uniprot/Q9PN94 Q9PN94]
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57844 57844]
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** [http://www.uniprot.org/uniprot/O26869 O26869]
* BIGG : met__L
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** [http://www.uniprot.org/uniprot/Q9JUT6 Q9JUT6]
{{#set: smiles=CSCCC([N+])C([O-])=O}}
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** [http://www.uniprot.org/uniprot/Q9CG55 Q9CG55]
{{#set: inchi key=InChIKey=FFEARJCKVFRZRR-BYPYZUCNSA-N}}
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** [http://www.uniprot.org/uniprot/P05694 P05694]
{{#set: common name=L-methionine}}
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** [http://www.uniprot.org/uniprot/Q42699 Q42699]
{{#set: molecular weight=149.207    }}
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** [http://www.uniprot.org/uniprot/Q39586 Q39586]
{{#set: common name=M|met|methionine|L-met}}
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** [http://www.uniprot.org/uniprot/O48613 O48613]
{{#set: consumed by=RXN-16165|RXN0-6948|S-ADENMETSYN-RXN|RME144|METHIONINE--TRNA-LIGASE-RXN}}
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** [http://www.uniprot.org/uniprot/P93263 P93263]
{{#set: produced by=RXN0-5063|R00946|RXN-8340|3.4.11.18-RXN|HOMOCYSTEINE-S-METHYLTRANSFERASE-RXN|RXN0-949|2.8.1.6-RXN|RXN-14950|RXN-14957|RXN-14959|HEMN-RXN|HOMOCYSMETB12-RXN|1.8.4.14-RXN|RXN-17473|RXN-17472|MMUM-RXN|RXN0-1342|FORMYLMETHIONINE-DEFORMYLASE-RXN|RXN-17878|RXN-17873|RXN-17877|RXN-17876|RXN-17875|RXN-17874|RXN-14480}}
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** [http://www.uniprot.org/uniprot/Q9UT19 Q9UT19]
{{#set: consumed or produced by=HOMOCYSMET-RXN}}
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{{#set: direction=REVERSIBLE}}
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{{#set: ec number=EC-2.1.1.14}}
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{{#set: gene associated=Tiso_gene_1602}}
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{{#set: in pathway=PWY-702|PWY-5041|PWY-6151|HSERMETANA-PWY|HOMOSER-METSYN-PWY}}
 +
{{#set: reconstruction category=annotation}}
 +
{{#set: reconstruction source=annotation-experimental_annotation|annotation-in-silico_annotation}}
 +
{{#set: reconstruction tool=pathwaytools}}

Latest revision as of 20:55, 21 March 2018

Reaction HOMOCYSMET-RXN

  • direction:
    • REVERSIBLE
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 N5-methyl--tetrahydropteroyl tri-L-glutamate[c] + 1 L-homocysteine[c] <=> 1 L-methionine[c] + 1 tetrahydropteroyl tri-L-glutamate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-702, L-methionine biosynthesis II: PWY-702
    • 5 reactions found over 6 reactions in the full pathway
  • PWY-5041, S-adenosyl-L-methionine cycle II: PWY-5041
    • 4 reactions found over 4 reactions in the full pathway
  • PWY-6151, S-adenosyl-L-methionine cycle I: PWY-6151
    • 4 reactions found over 6 reactions in the full pathway
  • HSERMETANA-PWY, L-methionine biosynthesis III: HSERMETANA-PWY
    • 3 reactions found over 4 reactions in the full pathway
  • HOMOSER-METSYN-PWY, L-methionine biosynthesis I: HOMOSER-METSYN-PWY
    • 4 reactions found over 5 reactions in the full pathway

Reconstruction information

External links