Difference between revisions of "PROGESTERONE-5-ALPHA-REDUCTASE-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=METHYLARSONITE METHYLARSONITE] == * smiles: ** C[As](O)O * common name: ** methylarsonite * inc...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=PROGESTERONE-5-ALPHA-REDUCTASE-RXN PROGESTERONE-5-ALPHA-REDUCTASE-RXN] == * direction: ** LEFT-TO-R...")
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=METHYLARSONITE METHYLARSONITE] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=PROGESTERONE-5-ALPHA-REDUCTASE-RXN PROGESTERONE-5-ALPHA-REDUCTASE-RXN] ==
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* smiles:
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* direction:
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** C[As](O)O
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** LEFT-TO-RIGHT
 
* common name:
 
* common name:
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** methylarsonite
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** 3-oxo-5-alpha-steroid_4-dehydrogenase
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* inchi key:
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* ec number:
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** InChIKey=OXBIRPQQKCQWGV-UHFFFAOYSA-N
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** [http://enzyme.expasy.org/EC/1.3.1.22 EC-1.3.1.22]
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* molecular weight:
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** 123.971   
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* Synonym(s):
 
* Synonym(s):
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** MMAIII
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** steroid 5-α-reductase
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** methylarsonous acid
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** Δ4-steroid 5α-reductase (progesterone)
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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* [[2.1.1.138-RXN]]
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* With identifiers:
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== Reaction(s) known to produce the compound ==
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** 1 [[NADPH]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[PROGESTERONE]][c] '''=>''' 1 [[NADP]][c] '''+''' 1 [[CPD-293]][c]
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== Reaction(s) of unknown directionality ==
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* With common name(s):
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** 1 NADPH[c] '''+''' 1 H+[c] '''+''' 1 progesterone[c] '''=>''' 1 NADP+[c] '''+''' 1 5-α-pregnane-3,20-dione[c]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Tiso_gene_14327]]
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** Source: [[annotation-in-silico_annotation]]
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*** Assignment: AUTOMATED-NAME-MATCH
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== Pathways  ==
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* [[PWY-6032]], cardenolide biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6032 PWY-6032]
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** '''1''' reactions found over '''3''' reactions in the full pathway
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* [[PWY-7455]], allopregnanolone biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7455 PWY-7455]
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** '''1''' reactions found over '''2''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[annotation]]
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** Source: [[annotation-in-silico_annotation]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* PUBCHEM:
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* RHEA:
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=161491 161491]
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21952 21952]
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* CHEMSPIDER:
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* LIGAND-RXN:
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** [http://www.chemspider.com/Chemical-Structure.141846.html 141846]
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** [http://www.genome.jp/dbget-bin/www_bget?R02208 R02208]
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* HMDB : HMDB12259
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{{#set: direction=LEFT-TO-RIGHT}}
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* CHEBI:
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{{#set: common name=3-oxo-5-alpha-steroid_4-dehydrogenase}}
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=17826 17826]
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{{#set: ec number=EC-1.3.1.22}}
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* LIGAND-CPD:
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{{#set: common name=steroid 5-α-reductase|Δ4-steroid 5α-reductase (progesterone)}}
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** [http://www.genome.jp/dbget-bin/www_bget?C07295 C07295]
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{{#set: gene associated=Tiso_gene_14327}}
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{{#set: smiles=C[As](O)O}}
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{{#set: in pathway=PWY-6032|PWY-7455}}
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{{#set: common name=methylarsonite}}
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{{#set: reconstruction category=annotation}}
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{{#set: inchi key=InChIKey=OXBIRPQQKCQWGV-UHFFFAOYSA-N}}
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{{#set: reconstruction source=annotation-in-silico_annotation}}
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{{#set: molecular weight=123.971    }}
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{{#set: reconstruction tool=pathwaytools}}
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{{#set: common name=MMAIII|methylarsonous acid}}
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{{#set: consumed by=2.1.1.138-RXN}}
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Latest revision as of 21:23, 21 March 2018

Reaction PROGESTERONE-5-ALPHA-REDUCTASE-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • 3-oxo-5-alpha-steroid_4-dehydrogenase
  • ec number:
  • Synonym(s):
    • steroid 5-α-reductase
    • Δ4-steroid 5α-reductase (progesterone)

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 NADPH[c] + 1 H+[c] + 1 progesterone[c] => 1 NADP+[c] + 1 5-α-pregnane-3,20-dione[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6032, cardenolide biosynthesis: PWY-6032
    • 1 reactions found over 3 reactions in the full pathway
  • PWY-7455, allopregnanolone biosynthesis: PWY-7455
    • 1 reactions found over 2 reactions in the full pathway

Reconstruction information

External links





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