Difference between revisions of "RXN-12570"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=5.99.1.3-RXN 5.99.1.3-RXN] == * direction: ** REVERSIBLE * common name: ** dna_topoisomerase ** ORF...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-12570 RXN-12570] == * direction: ** LEFT-TO-RIGHT * common name: ** 3-hydroxyacyl-_dehydrogenas...")
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=5.99.1.3-RXN 5.99.1.3-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-12570 RXN-12570] ==
 
* direction:
 
* direction:
** REVERSIBLE
+
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
** dna_topoisomerase
+
** 3-hydroxyacyl-_dehydrogenase
** ORF
+
** hydroxyacyl-coenzyme_a_dehydrogenase_3-ketoacyl-coenzyme_a_thiolase_enoyl-coenzyme_a_hydratasealpha_subunit
** dna_topoisomerase_6_subunit_a
+
** hydroxyacyl-coenzyme_a_mitochondrial
** dna_topoisomerase_2
+
 
* ec number:
 
* ec number:
** [http://enzyme.expasy.org/EC/5.99.1.3 EC-5.99.1.3]
+
** [http://enzyme.expasy.org/EC/1.1.1.35 EC-1.1.1.35]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
** 1 [[ATP]][c] '''+''' 1 [[Double-Stranded-DNAs]][c] '''<=>''' 1 [[Pi]][c] '''+''' 1 [[Negatively-super-coiled-DNAs]][c] '''+''' 1 [[ADP]][c]
+
** 1 [[K-HEXANOYL-COA]][c] '''+''' 1 [[PROTON]][c] '''+''' 1 [[NADH]][c] '''=>''' 1 [[OH-HEXANOYL-COA]][c] '''+''' 1 [[NAD]][c]
 
* With common name(s):
 
* With common name(s):
** 1 ATP[c] '''+''' 1 a double stranded DNA[c] '''<=>''' 1 phosphate[c] '''+''' 1 a negatively supercoiled DNA[c] '''+''' 1 ADP[c]
+
** 1 3-oxohexanoyl-CoA[c] '''+''' 1 H+[c] '''+''' 1 NADH[c] '''=>''' 1 (S)-3-hydroxyhexanoyl-CoA[c] '''+''' 1 NAD+[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
* Gene: [[Tiso_gene_828]]
+
* Gene: [[Tiso_gene_14026]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
** Source: [[orthology-esiliculosus]]
+
** Source: [[annotation-experimental_annotation]]
* Gene: [[Tiso_gene_3610]]
+
** Source: [[annotation-in-silico_annotation]]
+
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
* Gene: [[Tiso_gene_3374]]
 
 
** Source: [[orthology-esiliculosus]]
 
** Source: [[orthology-esiliculosus]]
* Gene: [[Tiso_gene_12629]]
+
* Gene: [[Tiso_gene_14027]]
** Source: [[annotation-in-silico_annotation]]
+
*** Assignment: EC-NUMBER
+
 
** Source: [[orthology-esiliculosus]]
 
** Source: [[orthology-esiliculosus]]
* Gene: [[Tiso_gene_1291]]
+
* Gene: [[Tiso_gene_5857]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
* Gene: [[Tiso_gene_3728]]
+
** Source: [[annotation-experimental_annotation]]
** Source: [[orthology-esiliculosus]]
+
*** Assignment: EC-NUMBER
* Gene: [[Tiso_gene_3396]]
+
** Source: [[orthology-athaliana]]
 
** Source: [[orthology-esiliculosus]]
 
** Source: [[orthology-esiliculosus]]
* Gene: [[Tiso_gene_6569]]
+
** Source: [[orthology-creinhardtii]]
 +
** Source: [[orthology-creinhardtii]]
 +
* Gene: [[Tiso_gene_14262]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
 
** Source: [[annotation-experimental_annotation]]
 
** Source: [[annotation-experimental_annotation]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
** Source: [[orthology-esiliculosus]]
+
* Gene: [[Tiso_gene_18838]]
* Gene: [[Tiso_gene_829]]
+
** Source: [[annotation-in-silico_annotation]]
 +
*** Assignment: EC-NUMBER
 +
* Gene: [[Tiso_gene_18839]]
 
** Source: [[annotation-in-silico_annotation]]
 
** Source: [[annotation-in-silico_annotation]]
 
*** Assignment: EC-NUMBER
 
*** Assignment: EC-NUMBER
** Source: [[orthology-esiliculosus]]
 
 
== Pathways  ==
 
== Pathways  ==
 +
* [[PWY-6863]], pyruvate fermentation to hexanol (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6863 PWY-6863]
 +
** '''5''' reactions found over '''11''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
 
* Category: [[orthology]]
 
* Category: [[orthology]]
 +
** Source: [[orthology-athaliana]]
 +
*** Tool: [[pantograph]]
 +
** Source: [[orthology-creinhardtii]]
 +
*** Tool: [[pantograph]]
 
** Source: [[orthology-esiliculosus]]
 
** Source: [[orthology-esiliculosus]]
 
*** Tool: [[pantograph]]
 
*** Tool: [[pantograph]]
Line 61: Line 64:
 
*** Tool: [[pathwaytools]]
 
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
* UNIPROT:
+
* RHEA:
** [http://www.uniprot.org/uniprot/Q7M3G2 Q7M3G2]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=31144 31144]
** [http://www.uniprot.org/uniprot/Q02880 Q02880]
+
* LIGAND-RXN:
** [http://www.uniprot.org/uniprot/P0A0K8 P0A0K8]
+
** [http://www.genome.jp/dbget-bin/www_bget?R04748 R04748]
** [http://www.uniprot.org/uniprot/P41515 P41515]
+
{{#set: direction=LEFT-TO-RIGHT}}
** [http://www.uniprot.org/uniprot/P12531 P12531]
+
{{#set: common name=3-hydroxyacyl-_dehydrogenase}}
** [http://www.uniprot.org/uniprot/P27570 P27570]
+
{{#set: common name=hydroxyacyl-coenzyme_a_dehydrogenase_3-ketoacyl-coenzyme_a_thiolase_enoyl-coenzyme_a_hydratasealpha_subunit}}
** [http://www.uniprot.org/uniprot/Q03470 Q03470]
+
{{#set: common name=hydroxyacyl-coenzyme_a_mitochondrial}}
** [http://www.uniprot.org/uniprot/P35810 P35810]
+
{{#set: ec number=EC-1.1.1.35}}
** [http://www.uniprot.org/uniprot/P43701 P43701]
+
{{#set: gene associated=Tiso_gene_14026|Tiso_gene_14027|Tiso_gene_5857|Tiso_gene_14262|Tiso_gene_18838|Tiso_gene_18839}}
** [http://www.uniprot.org/uniprot/Q9JX55 Q9JX55]
+
{{#set: in pathway=PWY-6863}}
** [http://www.uniprot.org/uniprot/Q9CH36 Q9CH36]
+
** [http://www.uniprot.org/uniprot/P20831 P20831]
+
** [http://www.uniprot.org/uniprot/Q9JTW5 Q9JTW5]
+
** [http://www.uniprot.org/uniprot/P33769 P33769]
+
** [http://www.uniprot.org/uniprot/P47250 P47250]
+
** [http://www.uniprot.org/uniprot/Q59189 Q59189]
+
** [http://www.uniprot.org/uniprot/P05652 P05652]
+
** [http://www.uniprot.org/uniprot/P43700 P43700]
+
** [http://www.uniprot.org/uniprot/P05653 P05653]
+
** [http://www.uniprot.org/uniprot/O87667 O87667]
+
** [http://www.uniprot.org/uniprot/Q9CGI5 Q9CGI5]
+
** [http://www.uniprot.org/uniprot/P23992 P23992]
+
** [http://www.uniprot.org/uniprot/P09176 P09176]
+
** [http://www.uniprot.org/uniprot/P06786 P06786]
+
** [http://www.uniprot.org/uniprot/P0AES6 P0AES6]
+
** [http://www.uniprot.org/uniprot/Q00942 Q00942]
+
** [http://www.uniprot.org/uniprot/P22447 P22447]
+
** [http://www.uniprot.org/uniprot/P08096 P08096]
+
** [http://www.uniprot.org/uniprot/P07065 P07065]
+
** [http://www.uniprot.org/uniprot/P0AES4 P0AES4]
+
** [http://www.uniprot.org/uniprot/P14829 P14829]
+
** [http://www.uniprot.org/uniprot/P77993 P77993]
+
** [http://www.uniprot.org/uniprot/P22840 P22840]
+
** [http://www.uniprot.org/uniprot/Q01320 Q01320]
+
** [http://www.uniprot.org/uniprot/P15348 P15348]
+
** [http://www.uniprot.org/uniprot/P13364 P13364]
+
** [http://www.uniprot.org/uniprot/P34203 P34203]
+
** [http://www.uniprot.org/uniprot/P50074 P50074]
+
** [http://www.uniprot.org/uniprot/P34031 P34031]
+
** [http://www.uniprot.org/uniprot/Q50404 Q50404]
+
** [http://www.uniprot.org/uniprot/Q50405 Q50405]
+
** [http://www.uniprot.org/uniprot/Q50406 Q50406]
+
** [http://www.uniprot.org/uniprot/P41513 P41513]
+
** [http://www.uniprot.org/uniprot/Q43906 Q43906]
+
** [http://www.uniprot.org/uniprot/P30182 P30182]
+
** [http://www.uniprot.org/uniprot/P37411 P37411]
+
** [http://www.uniprot.org/uniprot/P0A0L0 P0A0L0]
+
** [http://www.uniprot.org/uniprot/Q50435 Q50435]
+
** [http://www.uniprot.org/uniprot/P22446 P22446]
+
** [http://www.uniprot.org/uniprot/P77966 P77966]
+
** [http://www.uniprot.org/uniprot/Q48974 Q48974]
+
** [http://www.uniprot.org/uniprot/Q48995 Q48995]
+
** [http://www.uniprot.org/uniprot/Q49017 Q49017]
+
** [http://www.uniprot.org/uniprot/O68071 O68071]
+
** [http://www.uniprot.org/uniprot/O68140 O68140]
+
** [http://www.uniprot.org/uniprot/O24308 O24308]
+
** [http://www.uniprot.org/uniprot/Q57532 Q57532]
+
** [http://www.uniprot.org/uniprot/O41065 O41065]
+
** [http://www.uniprot.org/uniprot/Q9ZNN5 Q9ZNN5]
+
** [http://www.uniprot.org/uniprot/Q9ZNN4 Q9ZNN4]
+
** [http://www.uniprot.org/uniprot/Q9ZNN3 Q9ZNN3]
+
** [http://www.uniprot.org/uniprot/Q9ZNN2 Q9ZNN2]
+
** [http://www.uniprot.org/uniprot/Q9ZNN1 Q9ZNN1]
+
** [http://www.uniprot.org/uniprot/Q9ZNN0 Q9ZNN0]
+
** [http://www.uniprot.org/uniprot/O87117 O87117]
+
** [http://www.uniprot.org/uniprot/Q9WXF4 Q9WXF4]
+
** [http://www.uniprot.org/uniprot/O50627 O50627]
+
** [http://www.uniprot.org/uniprot/O50628 O50628]
+
** [http://www.uniprot.org/uniprot/P94604 P94604]
+
** [http://www.uniprot.org/uniprot/P94605 P94605]
+
** [http://www.uniprot.org/uniprot/Q9S5H9 Q9S5H9]
+
** [http://www.uniprot.org/uniprot/Q9ZNH3 Q9ZNH3]
+
** [http://www.uniprot.org/uniprot/Q9ZNH2 Q9ZNH2]
+
{{#set: direction=REVERSIBLE}}
+
{{#set: common name=dna_topoisomerase}}
+
{{#set: common name=ORF}}
+
{{#set: common name=dna_topoisomerase_6_subunit_a}}
+
{{#set: common name=dna_topoisomerase_2}}
+
{{#set: ec number=EC-5.99.1.3}}
+
{{#set: gene associated=Tiso_gene_828|Tiso_gene_3610|Tiso_gene_3374|Tiso_gene_12629|Tiso_gene_1291|Tiso_gene_3728|Tiso_gene_3396|Tiso_gene_6569|Tiso_gene_829}}
+
{{#set: in pathway=}}
+
 
{{#set: reconstruction category=orthology|annotation}}
 
{{#set: reconstruction category=orthology|annotation}}
{{#set: reconstruction source=annotation-experimental_annotation|annotation-in-silico_annotation|orthology-esiliculosus}}
+
{{#set: reconstruction source=annotation-experimental_annotation|orthology-creinhardtii|annotation-in-silico_annotation|orthology-athaliana|orthology-esiliculosus}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}
 
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 21:25, 21 March 2018

Reaction RXN-12570

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • 3-hydroxyacyl-_dehydrogenase
    • hydroxyacyl-coenzyme_a_dehydrogenase_3-ketoacyl-coenzyme_a_thiolase_enoyl-coenzyme_a_hydratasealpha_subunit
    • hydroxyacyl-coenzyme_a_mitochondrial
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 3-oxohexanoyl-CoA[c] + 1 H+[c] + 1 NADH[c] => 1 (S)-3-hydroxyhexanoyl-CoA[c] + 1 NAD+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6863, pyruvate fermentation to hexanol (engineered): PWY-6863
    • 5 reactions found over 11 reactions in the full pathway

Reconstruction information

External links