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	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
PORPHOBILSYNTH-RXN	EC-4.2.1.24	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 13382	PWY-5189 PWY-5188
PRAISOM-RXN	EC-5.3.1.24	Orthology Manual	Pantograph	Manual-primary network Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 10298 Tiso gene 10297	TRPSYN-PWY
PREPHENATEDEHYDRAT-RXN	EC-4.2.1.51	Orthology Manual Annotation	Pantograph Pathwaytools	Manual-primary network Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 5940 Tiso gene 6815	PWY-7432 PHESYN
PREPHENATEDEHYDROG-RXN	EC-1.3.1.12	Manual		Manual-primary network		PWY-7303 TYRSYN
PRIBFAICARPISOM-RXN	EC-5.3.1.16	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 11199 Tiso gene 1565	HISTSYN-PWY
PROTOPORGENOXI-RXN	EC-1.3.3.4	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 11986 Tiso gene 15401	PWY0-1415 HEME-BIOSYNTHESIS-II CHLOROPHYLL-SYN PWY-7159
PRPPAMIDOTRANS-RXN	EC-2.4.2.14	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 9914 Tiso gene 1007	PWY-6121 PWY-6122 PWY-7282 PWY-6277
PRPPSYN-RXN	EC-2.7.6.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 4677 Tiso gene 3025	PWY0-662
PRTRANS-RXN	EC-2.4.2.18	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 15839	TRPSYN-PWY
PSERTRANSAM-RXN	EC-2.6.1.52	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 17123 Tiso gene 15686	SERSYN-PWY
PYRROLINECARBREDUCT-RXN	EC-1.5.1.2	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 20218 Tiso gene 17059 Tiso gene 19254 Tiso gene 8625	PWY-6344 ARG-PRO-PWY PROSYN-PWY PWY-4981 PWY-3341
PYRUVATE-CARBOXYLASE-RXN	EC-6.4.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 15145 Tiso gene 15144 Tiso gene 2812	PWY-6142 PWY-6146 P42-PWY PWY-5750 PWY66-399
RIB5PISOM-RXN	EC-5.3.1.6	Orthology Manual Annotation	Pantograph Pathwaytools	Manual-primary network Orthology-athaliana Annotation-in-silico annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 18217	P124-PWY CALVIN-PWY PWY-5723 PWY-1861 P185-PWY NONOXIPENT-PWY
RIBULOSE-BISPHOSPHATE-CARBOXYLASE-RXN	EC-4.1.1.39	Orthology Manual	Pantograph	Manual-primary network Orthology-esiliculosus	Tiso gene 12199	PWY-5532 CALVIN-PWY PWY-5723
RIBULP3EPIM-RXN	EC-5.1.3.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 10879 Tiso gene 19140 Tiso gene 4754	P124-PWY CALVIN-PWY P21-PWY PWY-5723 PWY-1861 P122-PWY P185-PWY NONOXIPENT-PWY
RME144		Manual		Manual-primary network
RME255		Manual		Manual-primary network
RME256		Manual		Manual-primary network
RME294		Manual		Manual-primary network
RME295		Manual		Manual-primary network
RME296		Manual		Manual-primary network
RME297		Manual		Manual-primary network
RME298		Manual		Manual-primary network
RXN-10814	EC-2.6.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 13538 Tiso gene 17809 Tiso gene 15680 Tiso gene 17718 Tiso gene 6815 Tiso gene 12889	PWY-6318
RXN-11109	EC-3.6.4.13	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 13864 Tiso gene 15465 Tiso gene 14774 Tiso gene 17819 Tiso gene 13863 Tiso gene 5272 Tiso gene 11551 Tiso gene 13862 Tiso gene 9370 Tiso gene 17804
RXN-11832	EC-2.7.4.14 EC-2.7.4.25	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 2386 Tiso gene 14116 Tiso gene 19734 Tiso gene 9739	PWY-7205
RXN-12002	EC-2.7.4.22 EC-2.7.4.14	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Manual-primary network Orthology-creinhardtii	Tiso gene 14116 Tiso gene 2386 Tiso gene 19734 Tiso gene 9739 Tiso gene 17057	PWY-7176
RXN-12200	EC-3.6.1.5	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 20236 Tiso gene 12899	PWY-7185 PWY-7177
RXN-13158	EC-1.1.1.85	Orthology Manual Annotation	Pantograph Pathwaytools	Manual-primary network Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 2920
RXN-13163	EC-4.2.1.33	Manual Annotation	Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation	Tiso gene 12778
RXN-14014	EC-1.17.1.8	Orthology Manual	Pantograph	Manual-primary network Orthology-synechocystis Orthology-esiliculosus	Tiso gene 13314	PWY-5097 PWY-2942 DAPLYSINESYN-PWY PWY-2941
RXN-14047	EC-4.2.1.3	Manual Annotation	Pathwaytools	Manual-primary network Annotation-experimental annotation	Tiso gene 13007
RXN-14201	EC-3.6.1.5	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 20236 Tiso gene 12899
RXN-15878	EC-1.17.7.3	Manual		Manual-primary network		NONMEVIPP-PWY
RXN-5282		Manual		Manual-primary network		CHLOROPHYLL-SYN PWY-7159
RXN-5283		Manual		Manual-primary network		CHLOROPHYLL-SYN PWY-7159
RXN-5284		Manual		Manual-primary network		CHLOROPHYLL-SYN PWY-7159
RXN-5285	EC-1.3.1.33	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 10077 Tiso gene 17141 Tiso gene 19518	CHLOROPHYLL-SYN
RXN-5286	EC-1.3.1.75	Orthology Manual	Pantograph	Manual-primary network Orthology-creinhardtii	Tiso gene 13868	PWY-5526 PWY-5064 PWY-7760 PWY-7758 PWY-5086 PWY-7759
RXN-6182		Orthology Manual	Pantograph	Manual-primary network Orthology-esiliculosus	Tiso gene 19480
RXN-7663	EC-2.5.1.62	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Manual-primary network Annotation-in-silico annotation	Tiso gene 19542	PWY-5064
RXN-7716	EC-1.8.1.4	Orthology Manual	Pantograph	Manual-primary network Orthology-esiliculosus	Tiso gene 9330	PWY-5084
RXN-7737	EC-2.6.1.83	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 18833	PWY-5097
RXN-7903	EC-1.14.19.2	Manual Annotation	Pathwaytools	Manual-primary network Annotation-in-silico annotation	Tiso gene 6179	PWY-5147
RXN-8001	EC-1.1.1.23	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Manual-primary network Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation	Tiso gene 7381 Tiso gene 11386
RXN-8389	EC-1.14.19.2	Manual Annotation	Pathwaytools	Manual-primary network Annotation-in-silico annotation	Tiso gene 6179	PWY-5366
RXN-9514	EC-2.3.1.86 EC-2.3.1.85 EC-1.1.1.100	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 624 Tiso gene 10415 Tiso gene 9885 Tiso gene 135 Tiso gene 13083 Tiso gene 500 Tiso gene 13394 Tiso gene 16579 Tiso gene 136 Tiso gene 10876	PWY-5971 PWY-5994 PWY-7388
RXN-9515	EC-1.3.1.10 EC-1.3.1.39 EC-2.3.1.85 EC-2.3.1.86	Manual Annotation	Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation	Tiso gene 135 Tiso gene 13394 Tiso gene 10876 Tiso gene 500 Tiso gene 136	PWY-5994 PWY-7388
RXN-9516	EC-2.3.1.41	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 19302 Tiso gene 5939 Tiso gene 14485 Tiso gene 15991	PWY-5971 PWY-7388
RXN-9518	EC-2.3.1.86 EC-2.3.1.85 EC-1.1.1.100	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 10876 Tiso gene 13083 Tiso gene 135 Tiso gene 136 Tiso gene 13394 Tiso gene 9885 Tiso gene 500	PWY-5971 PWY-5994

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