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	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
ACETYL-COA-CARBOXYLTRANSFER-RXN	EC-6.4.1.2	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Annotation-experimental annotation Manual-primary network Orthology-esiliculosus	Tiso gene 3800 Tiso gene 5029 Tiso gene 2812 Tiso gene 7965	PWY-7388 PWY-6722 PWY-5743 PWY-5744 PWY-5789 PWY-6679 PWY-4381
ACP-S-ACETYLTRANSFER-RXN	EC-2.3.1.86 EC-2.3.1.85 EC-2.3.1.38	Orthology Manual Annotation	Pantograph Pathwaytools	Manual-primary network Orthology-athaliana Annotation-in-silico annotation Orthology-synechocystis	Tiso gene 13394 Tiso gene 15991 Tiso gene 10876 Tiso gene 136 Tiso gene 500 Tiso gene 135	PWY-5966 FASYN-INITIAL-PWY
ACSERLY-RXN	EC-2.5.1.47	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 6110 Tiso gene 12184 Tiso gene 2283 Tiso gene 819 Tiso gene 17043 Tiso gene 7852	CYSTSYN-PWY
ADENOSINE-KINASE-RXN	EC-2.7.1.20	Manual Annotation	Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation	Tiso gene 12078	PWY-6619
ADENOSYLHOMOCYSTEINASE-RXN	EC-3.3.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 14191	METHIONINE-DEG1-PWY PWY-5041
ADENYL-KIN-RXN	EC-2.7.4.3	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 694 Tiso gene 5837 Tiso gene 12257 Tiso gene 4816 Tiso gene 5839 Tiso gene 19036 Tiso gene 12256 Tiso gene 8576 Tiso gene 5387 Tiso gene 5081 Tiso gene 1453 Tiso gene 14116 Tiso gene 13477 Tiso gene 5388 Tiso gene 805 Tiso gene 3353 Tiso gene 19734	PWY-7219
ADENYLOSUCCINATE-SYNTHASE-RXN	EC-6.3.4.4	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 6453 Tiso gene 743	PWY-7219
ADPREDUCT-RXN	EC-1.17.4.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 10617 Tiso gene 9916 Tiso gene 10138 Tiso gene 9915	PWY-7220 PWY-7227
AICARSYN-RXN	EC-4.3.2.2	Manual Annotation	Pathwaytools	Manual-primary network Annotation-in-silico annotation		PWY-6123 PWY-6124 PWY-7234
AICARTRANSFORM-RXN	EC-2.1.2.3	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 18420	PWY-6123 PWY-6124
AIRCARBOXY-RXN	EC-4.1.1.21	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 16011	PWY-6124
AIRS-RXN	EC-6.3.3.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-synechocystis	Tiso gene 1369	PWY-6121 PWY-6122 PWY-6277
ALANINE--GLYOXYLATE-AMINOTRANSFERASE-RXN	EC-2.6.1.44	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-athaliana Orthology-esiliculosus	Tiso gene 11231 Tiso gene 6134 Tiso gene 5726	GLYSYN-ALA-PWY
ALANINE-AMINOTRANSFERASE-RXN	EC-2.6.1.2	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 5959 Tiso gene 10957	ALANINE-DEG3-PWY PWY-7383 PWY-7117 ALACAT2-PWY PWY-7115 ALANINE-SYN2-PWY
AMPSYN-RXN	EC-4.3.2.2	Manual Annotation	Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation		PWY-7219
ANTHRANSYN-RXN	EC-4.1.3.27	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 11176	TRPSYN-PWY PWY-5958 PWY-6661 PWY-6660
ARGSUCCINLYA-RXN	EC-4.3.2.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 2485	PWY-4984 ARGSYN-PWY PWY-5154 ARGSYNBSUB-PWY PWY-4983 PWY-7400
ARGSUCCINSYN-RXN	EC-6.3.4.5	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 12592	PWY-5154 ARGSYN-PWY PWY-4984 ARGSYNBSUB-PWY PWY-4983 PWY-7400
ASNSYNB-RXN	EC-6.3.5.4	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 2973 Tiso gene 7495	ASPARAGINE-BIOSYNTHESIS
ASPAMINOTRANS-RXN	EC-2.6.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 17809 Tiso gene 6815 Tiso gene 17718 Tiso gene 13538 Tiso gene 12889 Tiso gene 15680	PWY-5913 MALATE-ASPARTATE-SHUTTLE-PWY PWY-7383 ASPARTATE-DEG1-PWY ASPARTATESYN-PWY PWY-7117 GLUTDEG-PWY PWY-7115 ASPARAGINE-DEG1-PWY-1

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