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	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
3.1.3.46-RXN	EC-3.1.3.46	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-experimental annotation Annotation-in-silico annotation	Tiso gene 15398 Tiso gene 2100 Tiso gene 893 Tiso gene 892	PWY66-423
3.1.3.57-RXN	EC-3.1.3.57	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation	Tiso gene 12601	PWY-6363
3.1.3.67-RXN	EC-3.1.3.67	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 19083	PWY-6368
3.2.1.47-RXN	EC-3.2.1.47	Orthology	Pantograph	Orthology-athaliana	Tiso gene 3392
3PGAREARR-RXN	EC-5.4.2.12	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 16271 Tiso gene 5468 Tiso gene 14530 Tiso gene 7201 Tiso gene 20311 Tiso gene 2365 Tiso gene 10516 Tiso gene 16754 Tiso gene 9922 Tiso gene 2667 Tiso gene 15391 Tiso gene 2841 Tiso gene 15048 Tiso gene 14212 Tiso gene 9923 Tiso gene 14664	PWY-1042 P341-PWY PWY-2221 GLUCONEO-PWY GLYCOLYSIS PWY-6901 PWY-7218 P124-PWY PWY-6886 PWY-5723 PWY-6142 PWY-5484 PWY-7124 PWY-7003
4-COUMARATE--COA-LIGASE-RXN	EC-6.2.1.12	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 12275 Tiso gene 14183	PWY-6920 PWY-6435 PWY-7398 PWY-7046 PWY-361 PWY-7397 PWY-6320 PWY1F-FLAVSYN PWY-5754 PWY-5135 PWY-6982
4-HYDROXY-2-KETOPIMELATE-LYSIS-RXN	EC-4.1.2.52	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 13940	3-HYDROXYPHENYLACETATE-DEGRADATION-PWY
4-HYDROXYPHENYLPYRUVATE-DIOXYGENASE-RXN	EC-1.13.11.27	Orthology Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 18328 Tiso gene 18976 Tiso gene 18977	PWY-1581 PWY-7432 TYRFUMCAT-PWY PWY-1422
4.4.1.14-RXN	EC-4.4.1.14	Orthology Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 8455	ETHYL-PWY PWY-7270
5-OXOPROLINASE-ATP-HYDROLYSING-RXN	EC-3.5.2.9	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 3358 Tiso gene 3359	PWY-4041
6-PHOSPHOFRUCTO-2-KINASE-RXN	EC-2.7.1.105	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation	Tiso gene 2100 Tiso gene 892 Tiso gene 804 Tiso gene 893 Tiso gene 15398	PWY66-423
6.2.1.34-RXN	EC-6.2.1.34	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 12275 Tiso gene 14183	PWY-6343 PWY-1121
6PFRUCTPHOS-RXN	EC-2.7.1.11	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Manual-primary network Orthology-creinhardtii	Tiso gene 5733 Tiso gene 596	PWY-1042 GLYCOLYSIS PWY-7385 PWY-1861 ANAGLYCOLYSIS-PWY PWY-5484
6PGLUCONDEHYDROG-RXN	EC-1.1.1.351	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-synechocystis Orthology-esiliculosus	Tiso gene 20238 Tiso gene 91 Tiso gene 7157	P122-PWY
6PGLUCONOLACT-RXN	EC-3.1.1.31	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Manual-primary network Orthology-creinhardtii	Tiso gene 10799 Tiso gene 5901 Tiso gene 15950 Tiso gene 8585 Tiso gene 20412	P122-PWY RUMP-PWY OXIDATIVEPENT-PWY GLYCOLYSIS-E-D
7KAPSYN-RXN	EC-2.3.1.47	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 3555	PWY-6578
ACETYL-COA-ACETYLTRANSFER-RXN	EC-2.3.1.9	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-synechocystis Orthology-esiliculosus	Tiso gene 17451 Tiso gene 15327 Tiso gene 16181	P162-PWY PWY-5177 PWY-6583 P163-PWY PWY-6883 PWY-5676 PWY-6588 PWY-7779 PWY-7778 PWY1-3 PWY-5789 PWY-6876 CENTFERM-PWY PWY-7391 PWY-5741 PWY-6174 ACETOACETATE-DEG-PWY PWY66-367 PWY-7216 PWY-922 PWY66-368 PWY-7401 PWY-6863 PWY-7524
ACETYL-COA-CARBOXYLTRANSFER-RXN	EC-6.4.1.2	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Orthology-athaliana Annotation-experimental annotation Manual-primary network Orthology-esiliculosus	Tiso gene 3800 Tiso gene 5029 Tiso gene 2812 Tiso gene 7965	PWY-7388 PWY-6722 PWY-5743 PWY-5744 PWY-5789 PWY-6679 PWY-4381
ACETYLGLUTKIN-RXN	EC-2.7.2.8	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 13144	PWY-5154 GLUTORN-PWY ARGSYNBSUB-PWY
ACETYLORNDEACET-RXN	EC-3.5.1.16	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 16879 Tiso gene 16201	GLUTORN-PWY

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