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	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN	EC-1.2.1.11	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 18603	HOMOSERSYN-PWY PWY-7153 DAPLYSINESYN-PWY PWY-2942 PWY-2941 PWY-6559 PWY-6562 PWY-5097 P101-PWY
ASPARTATEKIN-RXN	EC-2.7.2.4	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 16097 Tiso gene 4345 Tiso gene 13809 Tiso gene 17057	HOMOSERSYN-PWY PWY-7153 DAPLYSINESYN-PWY PWY-2942 PWY-2941 PWY-6559 PWY-6562 PWY-5097 P101-PWY
ASPCARBTRANS-RXN	EC-2.1.3.2	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 13527	PWY-7790 PWY-7791 PWY-5686
ATPPHOSPHORIBOSYLTRANS-RXN	EC-2.4.2.17	Manual		Manual-primary network		HISTSYN-PWY
ATPSYN-RXN	EC-3.6.3.14	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 11754 Tiso gene 9460 Tiso gene 12618 Tiso gene 18105 Tiso gene 11192 Tiso gene 5307 Tiso gene 15850 Tiso gene 1366 Tiso gene 7213 Tiso gene 10981 Tiso gene 2798 Tiso gene 1365 Tiso gene 17383 Tiso gene 7215 Tiso gene 11753 Tiso gene 11155 Tiso gene 6012 Tiso gene 6592	PWY-7219
BRANCHED-CHAINAMINOTRANSFERILEU-RXN	EC-2.6.1.42	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 14984 Tiso gene 17748 Tiso gene 18403	ILEUSYN-PWY ILEUDEG-PWY PWY-5108 PWY-5103 PWY-5101 PWY-5078 PWY-5104
BRANCHED-CHAINAMINOTRANSFERLEU-RXN	EC-2.6.1.6 EC-2.6.1.42	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 18403 Tiso gene 14984	PWY-7767 LEU-DEG2-PWY LEUSYN-PWY PWY-5076
BRANCHED-CHAINAMINOTRANSFERVAL-RXN	EC-2.6.1.42	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-synechocystis Orthology-esiliculosus	Tiso gene 18403 Tiso gene 14984	VALSYN-PWY VALDEG-PWY ALANINE-VALINESYN-PWY PWY-5057
CARBPSYN-RXN	EC-6.3.5.5	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 4976 Tiso gene 4975 Tiso gene 4685	ARGSYN-PWY PWY-5154 PWY-7790 ARGSYNBSUB-PWY PWY-7400 PWY-7791 PWY-5686
CDPKIN-RXN	EC-2.7.4.6	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 16529 Tiso gene 17271 Tiso gene 17272 Tiso gene 195 Tiso gene 9290 Tiso gene 18224	PWY-7205
CDPREDUCT-RXN	EC-1.17.4.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 10617 Tiso gene 9916 Tiso gene 10138 Tiso gene 9915	PWY-7210 PWY-7198 PWY-6545 PWY0-166 PWY-7184
CHORISMATE-SYNTHASE-RXN	EC-4.2.3.5	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 9630	PWY-6163
CHORISMATEMUT-RXN	EC-5.4.99.5	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 5940	PHESYN PWY-6120 PWY-3462 PWY-3461 PWY-7626 TYRSYN PWY-6627
CITSYN-RXN	EC-2.3.3.16 EC-2.3.3.1	Manual Annotation	Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation	Tiso gene 9602 Tiso gene 9601 Tiso gene 18030 Tiso gene 9603	PWY-5913 PWY-7124 PWY-6969 PWY66-398 REDCITCYC P105-PWY GLYOXYLATE-BYPASS FERMENTATION-PWY PWY-6728 PWY-6549 PWY-7254 PWY-5690 PWY-5750 TCA
CTPSYN-RXN	EC-6.3.4.2	Manual Annotation	Pathwaytools	Annotation-in-silico annotation Manual-primary network Annotation-experimental annotation		PWY-7185 PWY-7176 PWY-7177
CYSTATHIONINE-BETA-LYASE-RXN		Manual		Manual-primary network
CYTOCHROME-C-OXIDASE-RXN	EC-1.9.3.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 18580 Tiso gene 7948 Tiso gene 15682 Tiso gene 18053	PWY-3781 PWY-7279 PWY-4521
CYTOCHROME-C-PEROXIDASE-RXN	EC-1.11.1.5	Manual Annotation	Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation	Tiso gene 11607 Tiso gene 4992 Tiso gene 4990 Tiso gene 5435 Tiso gene 19683 Tiso gene 11606
DADPKIN-RXN	EC-2.7.4.6	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 17271 Tiso gene 9290 Tiso gene 18224 Tiso gene 16529 Tiso gene 17272 Tiso gene 195	PWY-7220 PWY-7224 PWY-7227
DAHPSYN-RXN	EC-2.5.1.54	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Manual-primary network Orthology-creinhardtii	Tiso gene 7372 Tiso gene 18937 Tiso gene 18975 Tiso gene 8935 Tiso gene 8934	PWY-6164

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