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	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
ACP-S-ACETYLTRANSFER-RXN	EC-2.3.1.86 EC-2.3.1.85 EC-2.3.1.38	Orthology Manual Annotation	Pantograph Pathwaytools	Manual-primary network Orthology-athaliana Annotation-in-silico annotation Orthology-synechocystis	Tiso gene 13394 Tiso gene 15991 Tiso gene 10876 Tiso gene 136 Tiso gene 500 Tiso gene 135	PWY-5966 FASYN-INITIAL-PWY
ADCLY-RXN	EC-4.1.3.38	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 614 Tiso gene 17748	PWY-6543
ADENOSYLHOMOCYSTEINASE-RXN	EC-3.3.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 14191	METHIONINE-DEG1-PWY PWY-5041
ADENYL-KIN-RXN	EC-2.7.4.3	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 694 Tiso gene 5837 Tiso gene 12257 Tiso gene 4816 Tiso gene 5839 Tiso gene 19036 Tiso gene 12256 Tiso gene 8576 Tiso gene 5387 Tiso gene 5081 Tiso gene 1453 Tiso gene 14116 Tiso gene 13477 Tiso gene 5388 Tiso gene 805 Tiso gene 3353 Tiso gene 19734	PWY-7219
ADENYLYLSULFKIN-RXN	EC-2.7.1.25	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-synechocystis	Tiso gene 17878 Tiso gene 9490 Tiso gene 17879 Tiso gene 16197 Tiso gene 1110	PWY-5340
ADPREDUCT-RXN	EC-1.17.4.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 10617 Tiso gene 9916 Tiso gene 10138 Tiso gene 9915	PWY-7220 PWY-7227
AIRCARBOXY-RXN	EC-4.1.1.21	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 16011	PWY-6124
ALANINE--GLYOXYLATE-AMINOTRANSFERASE-RXN	EC-2.6.1.44	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-athaliana Orthology-esiliculosus	Tiso gene 11231 Tiso gene 6134 Tiso gene 5726	GLYSYN-ALA-PWY
ALANINE-AMINOTRANSFERASE-RXN	EC-2.6.1.2	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 5959 Tiso gene 10957	ALANINE-DEG3-PWY PWY-7383 PWY-7117 ALACAT2-PWY PWY-7115 ALANINE-SYN2-PWY
ALDHDEHYDROG-RXN	EC-1.2.1.3	Orthology	Pantograph	Orthology-athaliana	Tiso gene 7322 Tiso gene 3513	PWY-7269
ALDOSE-1-EPIMERASE-RXN	EC-5.1.3.3	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation	Tiso gene 19779 Tiso gene 17734	PWY0-1466
ALPHAGALACTOSID-RXN	EC-3.2.1.22	Orthology Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 2588 Tiso gene 16101 Tiso gene 8673 Tiso gene 4615 Tiso gene 3392	PWY0-1301
AMACETOXID-RXN	EC-1.4.3.21	Orthology	Pantograph	Orthology-athaliana Orthology-creinhardtii Orthology-esiliculosus	Tiso gene 8756 Tiso gene 18325	THRDLCTCAT-PWY
AMINEPHEN-RXN	EC-1.4.3.21	Orthology	Pantograph	Orthology-athaliana Orthology-esiliculosus	Tiso gene 8756	2PHENDEG-PWY PWY-5751
ANTHRANSYN-RXN	EC-4.1.3.27	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 11176	TRPSYN-PWY PWY-5958 PWY-6661 PWY-6660
ARGINASE-RXN	EC-3.5.3.1	Orthology Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 4415	ARGASEDEG-PWY PWY-6922 ARG-PRO-PWY ARG-GLU-PWY PWY-4984 PWY-6305 CITRULBIO-PWY
ARGSUCCINLYA-RXN	EC-4.3.2.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 2485	PWY-4984 ARGSYN-PWY PWY-5154 ARGSYNBSUB-PWY PWY-4983 PWY-7400
ARGSUCCINSYN-RXN	EC-6.3.4.5	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 12592	PWY-5154 ARGSYN-PWY PWY-4984 ARGSYNBSUB-PWY PWY-4983 PWY-7400
ASNSYNB-RXN	EC-6.3.5.4	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-athaliana Annotation-in-silico annotation Manual-primary network Orthology-esiliculosus	Tiso gene 2973 Tiso gene 7495	ASPARAGINE-BIOSYNTHESIS
ASPAMINOTRANS-RXN	EC-2.6.1.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 17809 Tiso gene 6815 Tiso gene 17718 Tiso gene 13538 Tiso gene 12889 Tiso gene 15680	PWY-5913 MALATE-ASPARTATE-SHUTTLE-PWY PWY-7383 ASPARTATE-DEG1-PWY ASPARTATESYN-PWY PWY-7117 GLUTDEG-PWY PWY-7115 ASPARAGINE-DEG1-PWY-1

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