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	Ec number	Reconstruction category	Reconstruction tool	Reconstruction source	Gene associated	In pathway
DCDPKIN-RXN	EC-2.7.4.6	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 16529 Tiso gene 9290 Tiso gene 17271 Tiso gene 195 Tiso gene 17272 Tiso gene 18224	PWY-7210 PWY-7198 PWY-7184 PWY-7197 PWY0-166 PWY-6545
DGDPKIN-RXN	EC-2.7.4.6	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 195 Tiso gene 17272 Tiso gene 17271 Tiso gene 16529 Tiso gene 18224 Tiso gene 9290	PWY-7222 PWY-7224 PWY-7226
DIAMINOPIMDECARB-RXN	EC-4.1.1.20	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 12041 Tiso gene 10737	PWY-5097 PWY-2942 DAPLYSINESYN-PWY PWY-2941
DIAMINOPIMEPIM-RXN	EC-5.1.1.7	Manual		Manual-primary network		PWY-5097 DAPLYSINESYN-PWY PWY-2941
DIHYDRODIPICSYN-RXN	EC-4.3.3.7	Orthology Manual Annotation	Pantograph Pathwaytools	Manual-primary network Annotation-in-silico annotation Orthology-esiliculosus	Tiso gene 14829	PWY-5097 PWY-2942 DAPLYSINESYN-PWY PWY-2941
DIHYDROFOLATEREDUCT-RXN	EC-1.5.1.3	Manual		Manual-primary network		1CMET2-PWY PWY-6614 PWY-3841
DIHYDROOROT-RXN	EC-3.5.2.3	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-in-silico annotation Manual-primary network Orthology-creinhardtii Orthology-synechocystis Annotation-experimental annotation	Tiso gene 15379	PWY-7790 PWY-7791 PWY-5686
DIHYDROXYISOVALDEHYDRAT-RXN	EC-4.2.1.9	Orthology Manual Annotation	Pantograph Pathwaytools	Manual-primary network Annotation-experimental annotation Orthology-athaliana Orthology-esiliculosus	Tiso gene 1563	VALSYN-PWY PWY-7111
DIHYDROXYMETVALDEHYDRAT-RXN	EC-4.2.1.9	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 1563	PWY-5103 ILEUSYN-PWY PWY-5101 PWY-5104
DTDPKIN-RXN	EC-2.7.4.6	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 9290 Tiso gene 17271 Tiso gene 18224 Tiso gene 17272 Tiso gene 16529 Tiso gene 195	PWY-7210 PWY-7198 PWY-7184 PWY-7187 PWY-7197 PWY0-166 PWY-6545
DTMPKI-RXN	EC-2.7.4.12 EC-2.7.4.13 EC-2.7.4.9	Manual Annotation	Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation	Tiso gene 3755	PWY-7210 PWY-7198 PWY-7184 PWY-7187 PWY-7197 PWY0-166 PWY-6545
DUDPKIN-RXN	EC-2.7.4.6	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 17271 Tiso gene 18224 Tiso gene 9290 Tiso gene 16529 Tiso gene 17272 Tiso gene 195	PWY-7184 PWY-6545 PWY0-166
DUTP-PYROP-RXN	EC-3.6.1.23 EC-3.6.1.9	Orthology Manual Annotation	Pantograph Pathwaytools	Manual-primary network Annotation-in-silico annotation Orthology-athaliana	Tiso gene 18793 Tiso gene 18792	PWY-7206 PWY-7184 PWY-7187 PWY-6545 PWY0-166
DXPREDISOM-RXN	EC-1.1.1.267	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 15169	NONMEVIPP-PWY PWY-7560
DXS-RXN	EC-2.2.1.7	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network Orthology-creinhardtii	Tiso gene 17311	NONMEVIPP-PWY PWY-6891 PWY-6892 PYRIDOXSYN-PWY PWY-7560
F16ALDOLASE-RXN	EC-4.1.2.13	Orthology Manual Annotation	Pantograph Pathwaytools	Orthology-creinhardtii Manual-primary network Annotation-in-silico annotation Annotation-experimental annotation Orthology-esiliculosus	Tiso gene 14568 Tiso gene 9118 Tiso gene 9119 Tiso gene 9179 Tiso gene 12272 Tiso gene 65	PWY-1042 P341-PWY GLUCONEO-PWY GLYCOLYSIS SUCSYN-PWY PWY-7385 ANAGLYCOLYSIS-PWY CALVIN-PWY PWY-1861 PWY-6142 PWY-5484 P185-PWY PWY66-399
F16BDEPHOS-RXN	EC-3.1.3.11	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Manual-primary network Orthology-creinhardtii	Tiso gene 4904 Tiso gene 3483 Tiso gene 4905 Tiso gene 15398 Tiso gene 9435 Tiso gene 8226 Tiso gene 16502	GLUCONEO-PWY SUCSYN-PWY GLYCOLYSIS CALVIN-PWY PWY-5484 P185-PWY PWY66-399
FARNESYLTRANSTRANSFERASE-RXN	EC-2.5.1.29	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 16284 Tiso gene 7305	PWY-7736 PWY-7492 PWY-6659 PWY-6691 PWY-5120 PWY-7720 PWY-7721 PWY-7517
FERREDOXIN--NITRITE-REDUCTASE-RXN	EC-1.7.7.1	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Orthology-esiliculosus Annotation-in-silico annotation Orthology-athaliana Orthology-synechocystis Manual-primary network	Tiso gene 7919	PWY-381 PWY490-3
FGAMSYN-RXN	EC-6.3.5.3	Orthology Manual Annotation	Pantograph Pathwaytools	Annotation-experimental annotation Manual-primary network Annotation-in-silico annotation Orthology-athaliana	Tiso gene 5865	PWY-6121 PWY-6122 PWY-6277

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