Difference between revisions of "PORPHOBILSYNTH-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-11671 CPD-11671] == * smiles: ** C(O)CC1(=CNC2(=C1C=C(O)C=C2)) * inchi key: ** InChIKey=KQR...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=PORPHOBILSYNTH-RXN PORPHOBILSYNTH-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** delta-ami...")
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-11671 CPD-11671] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=PORPHOBILSYNTH-RXN PORPHOBILSYNTH-RXN] ==
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* smiles:
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* direction:
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** C(O)CC1(=CNC2(=C1C=C(O)C=C2))
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** LEFT-TO-RIGHT
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* inchi key:
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** InChIKey=KQROHCSYOGBQGJ-UHFFFAOYSA-N
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* common name:
 
* common name:
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** 5-hydroxytryptophol
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** delta-aminolevulinic acid dehydratase (porphobilinogen synthase)
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* molecular weight:
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* ec number:
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** 177.202   
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** [http://enzyme.expasy.org/EC/4.2.1.24 EC-4.2.1.24]
 
* Synonym(s):
 
* Synonym(s):
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** hydroxytryptophol
 
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** 5-hydroxyindole-3-ethanol
 
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** 5-hydroxy-1H-indole-3-ethanol
 
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** 1H-indole-3-ethanol, 5-hydroxy-
 
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** indole-3-ethanol, 5-hydroxy-
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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== Reaction(s) known to produce the compound ==
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* With identifiers:
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* [[RXN-10781]]
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** 2 [[5-AMINO-LEVULINATE]][c] '''=>''' 1 [[PORPHOBILINOGEN]][c] '''+''' 2 [[WATER]][c] '''+''' 1 [[PROTON]][c]
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== Reaction(s) of unknown directionality ==
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* With common name(s):
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** 2 5-aminolevulinate[c] '''=>''' 1 porphobilinogen[c] '''+''' 2 H2O[c] '''+''' 1 H+[c]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[CHC_T00008491001]]
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** Source: [[annotation-original_genome]]
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*** Assignment: AUTOMATED-NAME-MATCH
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* Gene: [[CHC_T00008491001_1]]
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** Source: [[orthology-galdieria.sulphuraria]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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** Source: [[orthology-arabidopsis_thaliana]]
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== Pathways  ==
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* [[PWY-5189]], tetrapyrrole biosynthesis II (from glycine): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5189 PWY-5189]
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** '''4''' reactions found over '''4''' reactions in the full pathway
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* [[PWY-5188]], tetrapyrrole biosynthesis I (from glutamate): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5188 PWY-5188]
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** '''6''' reactions found over '''6''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[orthology]]
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** Source: [[orthology-arabidopsis_thaliana]]
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*** Tool: [[pantograph]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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*** Tool: [[pantograph]]
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** Source: [[orthology-galdieria.sulphuraria]]
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*** Tool: [[pantograph]]
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* Category: [[annotation]]
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** Source: [[annotation-original_genome]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* PUBCHEM:
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* RHEA:
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=9061 9061]
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=24064 24064]
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* CHEMSPIDER:
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* LIGAND-RXN:
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** [http://www.chemspider.com/Chemical-Structure.8708.html 8708]
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** [http://www.genome.jp/dbget-bin/www_bget?R00036 R00036]
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* HMDB : HMDB01855
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* UNIPROT:
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{{#set: smiles=C(O)CC1(=CNC2(=C1C=C(O)C=C2))}}
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** [http://www.uniprot.org/uniprot/P06214 P06214]
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{{#set: inchi key=InChIKey=KQROHCSYOGBQGJ-UHFFFAOYSA-N}}
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** [http://www.uniprot.org/uniprot/P13716 P13716]
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{{#set: common name=5-hydroxytryptophol}}
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** [http://www.uniprot.org/uniprot/Q7M315 Q7M315]
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{{#set: molecular weight=177.202    }}
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** [http://www.uniprot.org/uniprot/P30124 P30124]
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{{#set: common name=hydroxytryptophol|5-hydroxyindole-3-ethanol|5-hydroxy-1H-indole-3-ethanol|1H-indole-3-ethanol, 5-hydroxy-|indole-3-ethanol, 5-hydroxy-}}
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** [http://www.uniprot.org/uniprot/Q9JV37 Q9JV37]
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{{#set: produced by=RXN-10781}}
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** [http://www.uniprot.org/uniprot/P30950 P30950]
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** [http://www.uniprot.org/uniprot/Q60178 Q60178]
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** [http://www.uniprot.org/uniprot/Q9PNU5 Q9PNU5]
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** [http://www.uniprot.org/uniprot/Q59295 Q59295]
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** [http://www.uniprot.org/uniprot/Q02250 Q02250]
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** [http://www.uniprot.org/uniprot/P10518 P10518]
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** [http://www.uniprot.org/uniprot/Q43148 Q43148]
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** [http://www.uniprot.org/uniprot/Q42682 Q42682]
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** [http://www.uniprot.org/uniprot/Q43058 Q43058]
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** [http://www.uniprot.org/uniprot/Q59643 Q59643]
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** [http://www.uniprot.org/uniprot/Q9S8B1 Q9S8B1]
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** [http://www.uniprot.org/uniprot/P05373 P05373]
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** [http://www.uniprot.org/uniprot/P0ACB2 P0ACB2]
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** [http://www.uniprot.org/uniprot/Q42836 Q42836]
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** [http://www.uniprot.org/uniprot/P43210 P43210]
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** [http://www.uniprot.org/uniprot/Q9ZNC9 Q9ZNC9]
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{{#set: direction=LEFT-TO-RIGHT}}
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{{#set: common name=delta-aminolevulinic acid dehydratase (porphobilinogen synthase)}}
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{{#set: ec number=EC-4.2.1.24}}
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{{#set: gene associated=CHC_T00008491001|CHC_T00008491001_1}}
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{{#set: in pathway=PWY-5189|PWY-5188}}
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{{#set: reconstruction category=orthology|annotation}}
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{{#set: reconstruction source=annotation-original_genome|orthology-arabidopsis_thaliana|orthology-ectocarpus_siliculosus|orthology-galdieria.sulphuraria}}
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{{#set: reconstruction tool=pantograph|pathwaytools}}

Revision as of 16:30, 23 May 2018

Reaction PORPHOBILSYNTH-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • delta-aminolevulinic acid dehydratase (porphobilinogen synthase)
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-5189, tetrapyrrole biosynthesis II (from glycine): PWY-5189
    • 4 reactions found over 4 reactions in the full pathway
  • PWY-5188, tetrapyrrole biosynthesis I (from glutamate): PWY-5188
    • 6 reactions found over 6 reactions in the full pathway

Reconstruction information

External links





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