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| [[Category:Reaction]] | | [[Category:Reaction]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=UBIQUITIN--PROTEIN-LIGASE-RXN UBIQUITIN--PROTEIN-LIGASE-RXN] == | + | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-16378 RXN-16378] == |
| * direction: | | * direction: |
− | ** LEFT-TO-RIGHT | + | ** REVERSIBLE |
− | * common name:
| + | |
− | ** ubiquitin-activating enzyme E1
| + | |
| * ec number: | | * ec number: |
− | ** [http://enzyme.expasy.org/EC/6.2.1.45 EC-6.2.1.45] | + | ** [http://enzyme.expasy.org/EC/1.14.19.20 EC-1.14.19.20] |
| * Synonym(s): | | * Synonym(s): |
| | | |
| == Reaction Formula == | | == Reaction Formula == |
| * With identifiers: | | * With identifiers: |
− | ** 1 [[ATP]][c] '''+''' 1 [[Ubiquitin-C-Terminal-Glycine]][c] '''+''' 1 [[Ubiquitin-activating-protein-E1-L-cys]][c] '''=>''' 1 [[S-ubiquitinyl-UAP-E1-L-cysteine]][c] '''+''' 1 [[AMP]][c] '''+''' 1 [[PPI]][c] | + | ** 2 [[FERROCYTOCHROME-B5]][c] '''+''' 1 [[Delta7-Steroids]][c] '''+''' 2 [[PROTON]][c] '''+''' 1 [[OXYGEN-MOLECULE]][c] '''<=>''' 2 [[WATER]][c] '''+''' 1 [[Delta5-Delta7-Steroids]][c] '''+''' 2 [[FERRICYTOCHROME-B5]][c] |
| * With common name(s): | | * With common name(s): |
− | ** 1 ATP[c] '''+''' 1 a [ubiquitin] C-terminal glycine[c] '''+''' 1 an [E1 ubiquitin-activating enzyme]-L-cysteine[c] '''=>''' 1 an S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine[c] '''+''' 1 AMP[c] '''+''' 1 diphosphate[c] | + | ** 2 a ferrocytochrome b5[c] '''+''' 1 a Δ7-sterol[c] '''+''' 2 H+[c] '''+''' 1 oxygen[c] '''<=>''' 2 H2O[c] '''+''' 1 a Δ5,7-sterol[c] '''+''' 2 a ferricytochrome b5[c] |
| | | |
| == Genes associated with this reaction == | | == Genes associated with this reaction == |
| Genes have been associated with this reaction based on different elements listed below. | | Genes have been associated with this reaction based on different elements listed below. |
− | * [[CHC_T00008644001_1]] | + | * Gene: [[CHC_T00006481001_1]] |
− | ** [[pantograph]]-[[galdieria.sulphuraria]] | + | ** Source: [[orthology-galdieria.sulphuraria]] |
− | * [[CHC_T00010346001_1]]
| + | ** Source: [[orthology-ectocarpus_siliculosus]] |
− | ** [[pantograph]]-[[galdieria.sulphuraria]] | + | |
− | * [[CHC_T00005234001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00005531001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00006277001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00008443001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00010007001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00008502001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00006427001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00000387001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00004841001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00003230001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00002417001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00009358001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00004399001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00007701001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00010352001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00002791001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00005498001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00003966001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00006980001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00006794001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00002451001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00002169001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00009466001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00008828001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00009159001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00003204001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00008644001]]
| + | |
− | ** ORIGINAL_GENOME
| + | |
− | ***AUTOMATED-NAME-MATCH
| + | |
− | * [[CHC_T00010007001]]
| + | |
− | ** ORIGINAL_GENOME
| + | |
− | ***AUTOMATED-NAME-MATCH
| + | |
− | * [[CHC_T00000123001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00002999001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00004299001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00007651001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00004379001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
| == Pathways == | | == Pathways == |
− | * [[PWY-7511]], protein ubiquitylation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7511 PWY-7511]
| |
− | ** '''9''' reactions found over '''9''' reactions in the full pathway
| |
| == Reconstruction information == | | == Reconstruction information == |
− | * [[orthology]]: | + | * Category: [[orthology]] |
− | ** [[pantograph]]: | + | ** Source: [[orthology-ectocarpus_siliculosus]] |
− | *** [[galdieria.sulphuraria]] | + | *** Tool: [[pantograph]] |
− | * [[annotation]]: | + | ** Source: [[orthology-galdieria.sulphuraria]] |
− | ** [[pathwaytools]]:
| + | *** Tool: [[pantograph]] |
− | *** [[original_genome]] | + | |
| == External links == | | == External links == |
− | * LIGAND-RXN:
| + | {{#set: direction=REVERSIBLE}} |
− | ** [http://www.genome.jp/dbget-bin/www_bget?R03876 R03876]
| + | {{#set: ec number=EC-1.14.19.20}} |
− | * UNIPROT:
| + | {{#set: gene associated=CHC_T00006481001_1}} |
− | ** [http://www.uniprot.org/uniprot/P22314 P22314]
| + | {{#set: in pathway=}} |
− | ** [http://www.uniprot.org/uniprot/P49459 P49459]
| + | |
− | ** [http://www.uniprot.org/uniprot/P62256 P62256]
| + | |
− | ** [http://www.uniprot.org/uniprot/P63146 P63146]
| + | |
− | ** [http://www.uniprot.org/uniprot/P28263 P28263]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q02053 Q02053]
| + | |
− | ** [http://www.uniprot.org/uniprot/P62257 P62257]
| + | |
− | ** [http://www.uniprot.org/uniprot/P61088 P61088]
| + | |
− | ** [http://www.uniprot.org/uniprot/P63279 P63279]
| + | |
− | ** [http://www.uniprot.org/uniprot/P19812 P19812]
| + | |
− | ** [http://www.uniprot.org/uniprot/P21734 P21734]
| + | |
− | ** [http://www.uniprot.org/uniprot/P25869 P25869]
| + | |
− | ** [http://www.uniprot.org/uniprot/P31254 P31254]
| + | |
− | ** [http://www.uniprot.org/uniprot/P15731 P15731]
| + | |
− | ** [http://www.uniprot.org/uniprot/P15732 P15732]
| + | |
− | ** [http://www.uniprot.org/uniprot/P29340 P29340]
| + | |
− | ** [http://www.uniprot.org/uniprot/P35133 P35133]
| + | |
− | ** [http://www.uniprot.org/uniprot/P35134 P35134]
| + | |
− | ** [http://www.uniprot.org/uniprot/P35132 P35132]
| + | |
− | ** [http://www.uniprot.org/uniprot/P33296 P33296]
| + | |
− | ** [http://www.uniprot.org/uniprot/P22515 P22515]
| + | |
− | ** [http://www.uniprot.org/uniprot/P39940 P39940]
| + | |
− | ** [http://www.uniprot.org/uniprot/P42748 P42748]
| + | |
− | ** [http://www.uniprot.org/uniprot/P42750 P42750]
| + | |
− | ** [http://www.uniprot.org/uniprot/P42749 P42749]
| + | |
− | ** [http://www.uniprot.org/uniprot/P42747 P42747]
| + | |
− | ** [http://www.uniprot.org/uniprot/P50623 P50623]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q42973 Q42973]
| + | |
− | ** [http://www.uniprot.org/uniprot/P40984 P40984]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q92462 Q92462]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q42540 Q42540]
| + | |
− | ** [http://www.uniprot.org/uniprot/P93028 P93028]
| + | |
− | ** [http://www.uniprot.org/uniprot/P93393 P93393]
| + | |
− | ** [http://www.uniprot.org/uniprot/P31252 P31252]
| + | |
− | ** [http://www.uniprot.org/uniprot/P52486 P52486]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q9YGM6 Q9YGM6]
| + | |
− | ** [http://www.uniprot.org/uniprot/O42646 O42646]
| + | |
− | ** [http://www.uniprot.org/uniprot/O15979 O15979]
| + | |
− | ** [http://www.uniprot.org/uniprot/P23566 P23566]
| + | |
− | ** [http://www.uniprot.org/uniprot/Q96PU5 Q96PU5]
| + | |
− | ** [http://www.uniprot.org/uniprot/P27949 P27949]
| + | |
− | {{#set: direction=LEFT-TO-RIGHT}} | + | |
− | {{#set: common name=ubiquitin-activating enzyme E1}}
| + | |
− | {{#set: ec number=EC-6.2.1.45}} | + | |
− | {{#set: gene associated=CHC_T00008644001_1|CHC_T00010346001_1|CHC_T00005234001_1|CHC_T00005531001_1|CHC_T00006277001_1|CHC_T00008443001_1|CHC_T00010007001_1|CHC_T00008502001_1|CHC_T00006427001_1|CHC_T00000387001_1|CHC_T00004841001_1|CHC_T00003230001_1|CHC_T00002417001_1|CHC_T00009358001_1|CHC_T00004399001_1|CHC_T00007701001_1|CHC_T00010352001_1|CHC_T00002791001_1|CHC_T00005498001_1|CHC_T00003966001_1|CHC_T00006980001_1|CHC_T00006794001_1|CHC_T00002451001_1|CHC_T00002169001_1|CHC_T00009466001_1|CHC_T00008828001_1|CHC_T00009159001_1|CHC_T00003204001_1|CHC_T00008644001|CHC_T00010007001|CHC_T00000123001_1|CHC_T00002999001_1|CHC_T00004299001_1|CHC_T00007651001_1|CHC_T00004379001_1}} | + | |
− | {{#set: in pathway=PWY-7511}} | + | |
| {{#set: reconstruction category=orthology}} | | {{#set: reconstruction category=orthology}} |
| + | {{#set: reconstruction source=orthology-ectocarpus_siliculosus|orthology-galdieria.sulphuraria}} |
| {{#set: reconstruction tool=pantograph}} | | {{#set: reconstruction tool=pantograph}} |
− | {{#set: reconstruction source=galdieria.sulphuraria}}
| |
− | {{#set: reconstruction category=annotation}}
| |
− | {{#set: reconstruction tool=pathwaytools}}
| |
− | {{#set: reconstruction source=original_genome}}
| |
Genes have been associated with this reaction based on different elements listed below.