Difference between revisions of "GLYRIBONUCSYN-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=NADPH NADPH] == * smiles: ** C5(N(C1(OC(C(C1O)O)COP(OP(OCC4(C(C(C(N3(C2(=C(C(=NC=N2)N)N=C3)))O4...")
 
(One intermediate revision by the same user not shown)
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[[Category:Metabolite]]
+
[[Category:Reaction]]
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=NADPH NADPH] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLYRIBONUCSYN-RXN GLYRIBONUCSYN-RXN] ==
* smiles:
+
* direction:
** C5(N(C1(OC(C(C1O)O)COP(OP(OCC4(C(C(C(N3(C2(=C(C(=NC=N2)N)N=C3)))O4)OP([O-])([O-])=O)O))([O-])=O)(=O)[O-]))C=C(CC=5)C(=O)N)
+
** LEFT-TO-RIGHT
* inchi key:
+
* ec number:
** InChIKey=ACFIXJIJDZMPPO-NNYOXOHSSA-J
+
** [http://enzyme.expasy.org/EC/6.3.4.13 EC-6.3.4.13]
* common name:
+
** NADPH
+
* molecular weight:
+
** 741.394   
+
 
* Synonym(s):
 
* Synonym(s):
** reduced nicotinamide adenine dinucleotide phosphate
 
** NADPH2
 
** dihydrotriphosphopyridine nucleotide
 
** reduced dihydrotriphosphopyridine nucleotide
 
** dihydronicotinamide adenine dinucleotide phosphate
 
** dihydronicotinamide adenine dinucleotide phosphate reduced
 
** reduced NADP
 
** NADP-red
 
** TPNH
 
** dihydronicotinamide adenine dinucleotide-P
 
** β-NADPH
 
  
== Reaction(s) known to consume the compound ==
+
== Reaction Formula ==
* [[RXN1G-1053]]
+
* With identifiers:
* [[RXN-16562]]
+
** 1 [[5-P-BETA-D-RIBOSYL-AMINE]][c] '''+''' 1 [[ATP]][c] '''+''' 1 [[GLY]][c] '''=>''' 1 [[5-PHOSPHO-RIBOSYL-GLYCINEAMIDE]][c] '''+''' 1 [[Pi]][c] '''+''' 1 [[ADP]][c] '''+''' 1 [[PROTON]][c]
* [[RXN-4144]]
+
* With common name(s):
* [[RXN-7665]]
+
** 1 5-phospho-β-D-ribosylamine[c] '''+''' 1 ATP[c] '''+''' 1 glycine[c] '''=>''' 1 N1-(5-phospho-β-D-ribosyl)glycinamide[c] '''+''' 1 phosphate[c] '''+''' 1 ADP[c] '''+''' 1 H+[c]
* [[RXN-16616]]
+
 
* [[THIOREDOXIN-REDUCT-NADPH-RXN]]
+
== Genes associated with this reaction  ==
* [[RXN-7580]]
+
Genes have been associated with this reaction based on different elements listed below.
* [[RXN1G-508]]
+
* Gene: [[CHC_T00000892001_1]]
* [[RXN1G-349]]
+
** Source: [[orthology-galdieria.sulphuraria]]
* [[RXN-7664]]
+
** Source: [[orthology-ectocarpus_siliculosus]]
* [[RXN-600]]
+
** Source: [[orthology-arabidopsis_thaliana]]
* [[1.14.13.70-RXN]]
+
== Pathways  ==
* [[RXN-7666]]
+
* [[PWY-6122]], 5-aminoimidazole ribonucleotide biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6122 PWY-6122]
* [[RXN-8620]]
+
** '''5''' reactions found over '''5''' reactions in the full pathway
* [[RXN-13307]]
+
* [[PWY-6277]], superpathway of 5-aminoimidazole ribonucleotide biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6277 PWY-6277]
* [[RXN-13300]]
+
** '''7''' reactions found over '''9''' reactions in the full pathway
* [[RXN-17728]]
+
* [[PWY-6121]], 5-aminoimidazole ribonucleotide biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6121 PWY-6121]
* [[RXN-13308]]
+
** '''5''' reactions found over '''5''' reactions in the full pathway
* [[RXN66-12]]
+
== Reconstruction information  ==
* [[RXN-17743]]
+
* Category: [[orthology]]
* [[RXN-11726]]
+
** Source: [[orthology-galdieria.sulphuraria]]
* [[RXN-17744]]
+
*** Tool: [[pantograph]]
* [[FATTY-ACYL-COA-SYNTHASE-RXN]]
+
** Source: [[orthology-arabidopsis_thaliana]]
* [[1.2.1.13-RXN]]
+
*** Tool: [[pantograph]]
* [[RXN-7784]]
+
** Source: [[orthology-ectocarpus_siliculosus]]
* [[RXN-16626]]
+
*** Tool: [[pantograph]]
* [[RXN0-2142]]
+
* [[1.14.13.78-RXN]]
+
* [[RXN1G-358]]
+
* [[RXN-3142]]
+
* [[RXN-15046]]
+
* [[RXN-9344-CPD-10279/NADPH/PROTON//CPD-7845/CO-A/NADP.43.]]
+
* [[RXN-10625]]
+
* [[RXN-9234]]
+
* [[GLUTSEMIALDEHYDROG-RXN]]
+
* [[RXN-11911]]
+
* [[RXN-17428]]
+
* [[RXN-13707]]
+
* [[RXN-9536]]
+
* [[RXN-9532]]
+
* [[RXN-14014]]
+
* [[RXN-11881]]
+
* [[RXN-1106]]
+
* [[RXN1G-364]]
+
* [[RXN-1102]]
+
* [[RXN-1101]]
+
* [[RXN1G-287]]
+
* [[RXN-16765]]
+
* [[RXN-12747]]
+
* [[RXN-9633]]
+
* [[RXN-5962]]
+
* [[RXN0-300]]
+
* [[RXN-9524]]
+
* [[RXN-9528]]
+
* [[RXN1A0-6303]]
+
* [[RXN0-1281]]
+
* [[RXN-5282]]
+
* [[RXN-5283]]
+
* [[RXN-5284]]
+
* [[RXN-5285]]
+
* [[RXN-5286]]
+
* [[RXN-12568-HEXANAL/CO-A/NADP//HEXANOYL-COA/NADPH/PROTON.45.]]
+
* [[GLUTRNAREDUCT-RXN]]
+
* [[RXN-14973]]
+
* [[RXN-9540]]
+
* [[RXN-9556]]
+
* [[RXN-13724]]
+
* [[RXN-9552]]
+
* [[SULFITE-REDUCT-RXN]]
+
* [[KYNURENINE-3-MONOOXYGENASE-RXN]]
+
* [[SHIKIMATE-5-DEHYDROGENASE-RXN]]
+
* [[RXN1G-881]]
+
* [[RXN-1125]]
+
* [[RXN-10060]]
+
* [[RXN1G-157]]
+
* [[RXN-1121]]
+
* [[RXN1G-469]]
+
* [[RXN1G-260]]
+
* [[TRANSENOYLCOARED-RXN-HEXANOYL-COA/NADP//CPD0-2121/NADPH/PROTON.42.]]
+
* [[RXN-10717]]
+
* [[RXN-14972]]
+
* [[RXN66-28]]
+
* [[RXN-9546]]
+
* [[RIBOFLAVINSYNREDUC-RXN]]
+
* [[RXN-12293]]
+
* [[FLAVONADPREDUCT-RXN]]
+
* [[RXN-10655]]
+
* [[RXN-7651]]
+
* [[PYRNUTRANSHYDROGEN-RXN]]
+
* [[RXN-10659]]
+
* [[RXN1G-163]]
+
* [[RXN-16622]]
+
* [[TRANS-CINNAMATE-4-MONOOXYGENASE-RXN]]
+
* [[2-DEHYDROPANTOATE-REDUCT-RXN]]
+
* [[HOMOSERDEHYDROG-RXN-HOMO-SER/NADP//L-ASPARTATE-SEMIALDEHYDE/NADPH/PROTON.53.]]
+
* [[TRANSENOYLCOARED-RXN]]
+
* [[RXN-13299]]
+
* [[RXN-16016]]
+
* [[RXN3O-130]]
+
* [[RXN66-13]]
+
* [[RXN66-11]]
+
* [[ACETOOHBUTREDUCTOISOM-RXN]]
+
* [[RXN-17897]]
+
* [[GLUTATHIONE-REDUCT-NADPH-RXN]]
+
* [[RXN-15006]]
+
* [[RXN-13191]]
+
* [[RXN66-14]]
+
* [[RXN-12510]]
+
* [[RXN-9279]]
+
* [[RXN-8619]]
+
* [[RXN-11476]]
+
* [[RXN-13961]]
+
* [[RXN-13008]]
+
* [[RXN1G-240]]
+
* [[RXN-16630]]
+
* [[RXN66-305]]
+
* [[RXN66-304]]
+
* [[RXN66-306]]
+
* [[QOR-RXN]]
+
* [[DIHYDROFOLATEREDUCT-RXN-THF/NADP//DIHYDROFOLATE/NADPH/PROTON.37.]]
+
* [[ALCOHOL-DEHYDROGENASE-NADPORNOP+-RXN]]
+
* [[MALATE-DEHYDROGENASE-NADP+-RXN]]
+
* [[RXN66-303]]
+
* [[RXN-11480]]
+
* [[RXN66-482]]
+
* [[3-OXOACYL-ACP-REDUCT-RXN]]
+
* [[RXN1G-72]]
+
* [[RXN-9725]]
+
* [[RXN-14023]]
+
* [[DIHYDROKAEMPFEROL-4-REDUCTASE-RXN]]
+
* [[RXN-5242]]
+
* [[DIHYDROFOLATEREDUCT-RXN]]
+
* [[RXN-9518]]
+
* [[RXN-9514]]
+
* [[3-DEHYDROSPHINGANINE-REDUCTASE-RXN]]
+
== Reaction(s) known to produce the compound ==
+
* [[SUCCSEMIALDDEHYDROG-RXN]]
+
* [[RXN-924]]
+
* [[RXN-8014]]
+
* [[MALIC-NADP-RXN]]
+
* [[1.18.1.2-RXN]]
+
* [[TRANS-RXN0-277]]
+
* [[2.1.1.135-RXN]]
+
* [[RXN-9952]]
+
* [[GLU6PDEHYDROG-RXN]]
+
== Reaction(s) of unknown directionality ==
+
* [[RXN-7660]]
+
* [[ISOCITDEH-RXN]]
+
* [[RXN-1124]]
+
* [[GLUTDEHYD-RXN]]
+
* [[METHYLENETHFDEHYDROG-NADP-RXN]]
+
* [[1.1.1.34-RXN]]
+
* [[FATTY-ACID-SYNTHASE-RXN]]
+
* [[RXN-10841]]
+
* [[DXPREDISOM-RXN]]
+
* [[RXN-7659]]
+
* [[RXN-7658]]
+
* [[RXN-12645]]
+
* [[PREPHENATE-DEHYDROGENASE-NADP+-RXN]]
+
* [[RXN-12642]]
+
* [[CARBONYL-REDUCTASE-NADPH-RXN]]
+
* [[ENZRXN-201-RXN]]
+
* [[BUTANAL-DEHYDROGENASE-RXN-BUTANAL/CO-A/NADP//BUTYRYL-COA/NADPH/PROTON.44.]]
+
* [[RXN-9951]]
+
* [[RXN-12484]]
+
* [[RXN-701]]
+
* [[ACETOLACTREDUCTOISOM-RXN]]
+
* [[ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN]]
+
* [[RXN1F-10]]
+
* [[RXN1F-72]]
+
* [[N-ACETYLGLUTPREDUCT-RXN]]
+
* [[RXN-14209]]
+
* [[RXN-12303-PLASTOQUINONE-9/NADPH/PROTON//CPD-12829/NADP.45.]]
+
 
== External links  ==
 
== External links  ==
* CAS : 2646-71-1
+
* RHEA:
* METABOLIGHTS : MTBLC57783
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=17453 17453]
* PUBCHEM:
+
* UNIPROT:
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=15983949 15983949]
+
** [http://www.uniprot.org/uniprot/P07244 P07244]
* HMDB : HMDB00221
+
** [http://www.uniprot.org/uniprot/Q58347 Q58347]
* LIGAND-CPD:
+
** [http://www.uniprot.org/uniprot/P12039 P12039]
** [http://www.genome.jp/dbget-bin/www_bget?C00005 C00005]
+
** [http://www.uniprot.org/uniprot/P21872 P21872]
* CHEMSPIDER:
+
** [http://www.uniprot.org/uniprot/P15640 P15640]
** [http://www.chemspider.com/Chemical-Structure.10239199.html 10239199]
+
** [http://www.uniprot.org/uniprot/P00967 P00967]
* CHEBI:
+
** [http://www.uniprot.org/uniprot/P16340 P16340]
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57783 57783]
+
** [http://www.uniprot.org/uniprot/P22102 P22102]
* BIGG : nadph
+
** [http://www.uniprot.org/uniprot/Q9JWU6 Q9JWU6]
{{#set: smiles=C5(N(C1(OC(C(C1O)O)COP(OP(OCC4(C(C(C(N3(C2(=C(C(=NC=N2)N)N=C3)))O4)OP([O-])([O-])=O)O))([O-])=O)(=O)[O-]))C=C(CC=5)C(=O)N)}}
+
** [http://www.uniprot.org/uniprot/P43845 P43845]
{{#set: inchi key=InChIKey=ACFIXJIJDZMPPO-NNYOXOHSSA-J}}
+
** [http://www.uniprot.org/uniprot/Q9PN47 Q9PN47]
{{#set: common name=NADPH}}
+
** [http://www.uniprot.org/uniprot/Q64737 Q64737]
{{#set: molecular weight=741.394    }}
+
** [http://www.uniprot.org/uniprot/P20772 P20772]
{{#set: common name=reduced nicotinamide adenine dinucleotide phosphate|NADPH2|dihydrotriphosphopyridine nucleotide|reduced dihydrotriphosphopyridine nucleotide|dihydronicotinamide adenine dinucleotide phosphate|dihydronicotinamide adenine dinucleotide phosphate reduced|reduced NADP|NADP-red|TPNH|dihydronicotinamide adenine dinucleotide-P|β-NADPH}}
+
** [http://www.uniprot.org/uniprot/P26977 P26977]
{{#set: consumed by=RXN1G-1053|RXN-16562|RXN-4144|RXN-7665|RXN-16616|THIOREDOXIN-REDUCT-NADPH-RXN|RXN-7580|RXN1G-508|RXN1G-349|RXN-7664|RXN-600|1.14.13.70-RXN|RXN-7666|RXN-8620|RXN-13307|RXN-13300|RXN-17728|RXN-13308|RXN66-12|RXN-17743|RXN-11726|RXN-17744|FATTY-ACYL-COA-SYNTHASE-RXN|1.2.1.13-RXN|RXN-7784|RXN-16626|RXN0-2142|1.14.13.78-RXN|RXN1G-358|RXN-3142|RXN-15046|RXN-9344-CPD-10279/NADPH/PROTON//CPD-7845/CO-A/NADP.43.|RXN-10625|RXN-9234|GLUTSEMIALDEHYDROG-RXN|RXN-11911|RXN-17428|RXN-13707|RXN-9536|RXN-9532|RXN-14014|RXN-11881|RXN-1106|RXN1G-364|RXN-1102|RXN-1101|RXN1G-287|RXN-16765|RXN-12747|RXN-9633|RXN-5962|RXN0-300|RXN-9524|RXN-9528|RXN1A0-6303|RXN0-1281|RXN-5282|RXN-5283|RXN-5284|RXN-5285|RXN-5286|RXN-12568-HEXANAL/CO-A/NADP//HEXANOYL-COA/NADPH/PROTON.45.|GLUTRNAREDUCT-RXN|RXN-14973|RXN-9540|RXN-9556|RXN-13724|RXN-9552|SULFITE-REDUCT-RXN|KYNURENINE-3-MONOOXYGENASE-RXN|SHIKIMATE-5-DEHYDROGENASE-RXN|RXN1G-881|RXN-1125|RXN-10060|RXN1G-157|RXN-1121|RXN1G-469|RXN1G-260|TRANSENOYLCOARED-RXN-HEXANOYL-COA/NADP//CPD0-2121/NADPH/PROTON.42.|RXN-10717|RXN-14972|RXN66-28|RXN-9546|RIBOFLAVINSYNREDUC-RXN|RXN-12293|FLAVONADPREDUCT-RXN|RXN-10655|RXN-7651|PYRNUTRANSHYDROGEN-RXN|RXN-10659|RXN1G-163|RXN-16622|TRANS-CINNAMATE-4-MONOOXYGENASE-RXN|2-DEHYDROPANTOATE-REDUCT-RXN|HOMOSERDEHYDROG-RXN-HOMO-SER/NADP//L-ASPARTATE-SEMIALDEHYDE/NADPH/PROTON.53.|TRANSENOYLCOARED-RXN|RXN-13299|RXN-16016|RXN3O-130|RXN66-13|RXN66-11|ACETOOHBUTREDUCTOISOM-RXN|RXN-17897|GLUTATHIONE-REDUCT-NADPH-RXN|RXN-15006|RXN-13191|RXN66-14|RXN-12510|RXN-9279|RXN-8619|RXN-11476|RXN-13961|RXN-13008|RXN1G-240|RXN-16630|RXN66-305|RXN66-304|RXN66-306|QOR-RXN|DIHYDROFOLATEREDUCT-RXN-THF/NADP//DIHYDROFOLATE/NADPH/PROTON.37.|ALCOHOL-DEHYDROGENASE-NADPORNOP+-RXN|MALATE-DEHYDROGENASE-NADP+-RXN|RXN66-303|RXN-11480|RXN66-482|3-OXOACYL-ACP-REDUCT-RXN|RXN1G-72|RXN-9725|RXN-14023|DIHYDROKAEMPFEROL-4-REDUCTASE-RXN|RXN-5242|DIHYDROFOLATEREDUCT-RXN|RXN-9518|RXN-9514|3-DEHYDROSPHINGANINE-REDUCTASE-RXN}}
+
** [http://www.uniprot.org/uniprot/Q59492 Q59492]
{{#set: produced by=SUCCSEMIALDDEHYDROG-RXN|RXN-924|RXN-8014|MALIC-NADP-RXN|1.18.1.2-RXN|TRANS-RXN0-277|2.1.1.135-RXN|RXN-9952|GLU6PDEHYDROG-RXN}}
+
** [http://www.uniprot.org/uniprot/P74232 P74232]
{{#set: consumed or produced by=RXN-7660|ISOCITDEH-RXN|RXN-1124|GLUTDEHYD-RXN|METHYLENETHFDEHYDROG-NADP-RXN|1.1.1.34-RXN|FATTY-ACID-SYNTHASE-RXN|RXN-10841|DXPREDISOM-RXN|RXN-7659|RXN-7658|RXN-12645|PREPHENATE-DEHYDROGENASE-NADP+-RXN|RXN-12642|CARBONYL-REDUCTASE-NADPH-RXN|ENZRXN-201-RXN|BUTANAL-DEHYDROGENASE-RXN-BUTANAL/CO-A/NADP//BUTYRYL-COA/NADPH/PROTON.44.|RXN-9951|RXN-12484|RXN-701|ACETOLACTREDUCTOISOM-RXN|ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN|RXN1F-10|RXN1F-72|N-ACETYLGLUTPREDUCT-RXN|RXN-14209|RXN-12303-PLASTOQUINONE-9/NADPH/PROTON//CPD-12829/NADP.45.}}
+
** [http://www.uniprot.org/uniprot/Q42804 Q42804]
 +
** [http://www.uniprot.org/uniprot/P52421 P52421]
 +
* LIGAND-RXN:
 +
** [http://www.genome.jp/dbget-bin/www_bget?R04144 R04144]
 +
{{#set: direction=LEFT-TO-RIGHT}}
 +
{{#set: ec number=EC-6.3.4.13}}
 +
{{#set: gene associated=CHC_T00000892001_1}}
 +
{{#set: in pathway=PWY-6122|PWY-6277|PWY-6121}}
 +
{{#set: reconstruction category=orthology}}
 +
{{#set: reconstruction source=orthology-galdieria.sulphuraria|orthology-arabidopsis_thaliana|orthology-ectocarpus_siliculosus}}
 +
{{#set: reconstruction tool=pantograph}}

Latest revision as of 15:17, 9 January 2019

Reaction GLYRIBONUCSYN-RXN

  • direction:
    • LEFT-TO-RIGHT
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6122, 5-aminoimidazole ribonucleotide biosynthesis II: PWY-6122
    • 5 reactions found over 5 reactions in the full pathway
  • PWY-6277, superpathway of 5-aminoimidazole ribonucleotide biosynthesis: PWY-6277
    • 7 reactions found over 9 reactions in the full pathway
  • PWY-6121, 5-aminoimidazole ribonucleotide biosynthesis I: PWY-6121
    • 5 reactions found over 5 reactions in the full pathway

Reconstruction information

External links