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− | [[Category:Reaction]] | + | [[Category:Metabolite]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=SUCCCOASYN-RXN SUCCCOASYN-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=HISTIDINOL HISTIDINOL] == |
− | * direction: | + | * smiles: |
− | ** REVERSIBLE | + | ** C1(NC=NC=1CC(CO)[N+]) |
− | * ec number: | + | * molecular weight: |
− | ** [http://enzyme.expasy.org/EC/6.2.1.5 EC-6.2.1.5] | + | ** 142.18 |
| + | * inchi key: |
| + | ** InChIKey=ZQISRDCJNBUVMM-YFKPBYRVSA-O |
| + | * common name: |
| + | ** histidinol |
| * Synonym(s): | | * Synonym(s): |
− | ** Succinate thiokinase | + | ** histidol |
− | ** succinyl CoA synthesis | + | ** L-histidinol |
| | | |
− | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
− | * With identifiers:
| + | * [[RXN-8001]] |
− | ** 1 [[SUC]][c] '''+''' 1 [[ATP]][c] '''+''' 1 [[CO-A]][c] '''<=>''' 1 [[ADP]][c] '''+''' 1 [[Pi]][c] '''+''' 1 [[SUC-COA]][c]
| + | == Reaction(s) known to produce the compound == |
− | * With common name(s):
| + | * [[HISTIDPHOS-RXN[CCO-CYTOSOL]-L-HISTIDINOL-P/WATER//HISTIDINOL/Pi.49.]] |
− | ** 1 succinate[c] '''+''' 1 ATP[c] '''+''' 1 coenzyme A[c] '''<=>''' 1 ADP[c] '''+''' 1 phosphate[c] '''+''' 1 succinyl-CoA[c]
| + | * [[HISTIDPHOS-RXN]] |
− | | + | == Reaction(s) of unknown directionality == |
− | == Genes associated with this reaction ==
| + | * [[HISTOLDEHYD-RXN]] |
− | Genes have been associated with this reaction based on different elements listed below.
| + | |
− | * [[CHC_T00008602001_1]] | + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | ** [[pantograph]]-[[a.taliana]]
| + | |
− | * [[CHC_T00009212001_1]]
| + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | ** [[pantograph]]-[[a.taliana]]
| + | |
− | == Pathways == | + | |
− | * [[PWY-5913]], partial TCA cycle (obligate autotrophs): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5913 PWY-5913]
| + | |
− | ** '''10''' reactions found over '''11''' reactions in the full pathway
| + | |
− | * [[P42-PWY]], incomplete reductive TCA cycle: [http://metacyc.org/META/NEW-IMAGE?object=P42-PWY P42-PWY]
| + | |
− | ** '''3''' reactions found over '''7''' reactions in the full pathway
| + | |
− | * [[PWY-7384]], anaerobic energy metabolism (invertebrates, mitochondrial): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7384 PWY-7384]
| + | |
− | ** '''5''' reactions found over '''12''' reactions in the full pathway
| + | |
− | * [[PWY-5392]], reductive TCA cycle II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5392 PWY-5392] | + | |
− | ** '''5''' reactions found over '''12''' reactions in the full pathway
| + | |
− | * [[P23-PWY]], reductive TCA cycle I: [http://metacyc.org/META/NEW-IMAGE?object=P23-PWY P23-PWY]
| + | |
− | ** '''9''' reactions found over '''12''' reactions in the full pathway
| + | |
− | * [[PWY-6969]], TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6969 PWY-6969]
| + | |
− | ** '''8''' reactions found over '''12''' reactions in the full pathway
| + | |
− | * [[PWY-5537]], pyruvate fermentation to acetate V: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5537 PWY-5537]
| + | |
− | ** '''2''' reactions found over '''4''' reactions in the full pathway
| + | |
− | * [[PWY-6728]], methylaspartate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6728 PWY-6728]
| + | |
− | ** '''9''' reactions found over '''18''' reactions in the full pathway
| + | |
− | * [[PWY-5538]], pyruvate fermentation to acetate VI: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5538 PWY-5538]
| + | |
− | ** '''1''' reactions found over '''4''' reactions in the full pathway
| + | |
− | * [[PWY-5690]], TCA cycle II (plants and fungi): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5690 PWY-5690] | + | |
− | ** '''9''' reactions found over '''9''' reactions in the full pathway
| + | |
− | * [[PWY66-398]], TCA cycle III (animals): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-398 PWY66-398]
| + | |
− | ** '''10''' reactions found over '''11''' reactions in the full pathway
| + | |
− | * [[TCA]], TCA cycle I (prokaryotic): [http://metacyc.org/META/NEW-IMAGE?object=TCA TCA]
| + | |
− | ** '''9''' reactions found over '''10''' reactions in the full pathway
| + | |
− | == Reconstruction information ==
| + | |
− | * [[orthology]]: | + | |
− | ** [[pantograph]]:
| + | |
− | *** [[galdieria.sulphuraria]]
| + | |
− | *** [[a.taliana]]
| + | |
| == External links == | | == External links == |
− | * RHEA: | + | * KNAPSACK : C00007479 |
− | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=17661 17661] | + | * BIGG : histd |
− | * LIGAND-RXN: | + | * CAS : 501-28-0 |
− | ** [http://www.genome.jp/dbget-bin/www_bget?R00405 R00405] | + | * HMDB : HMDB03431 |
− | * UNIPROT: | + | * CHEBI: |
− | ** [http://www.uniprot.org/uniprot/O28098 O28098] | + | ** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57699 57699] |
− | ** [http://www.uniprot.org/uniprot/P53594 P53594]
| + | * LIGAND-CPD: |
− | ** [http://www.uniprot.org/uniprot/O28733 O28733]
| + | ** [http://www.genome.jp/dbget-bin/www_bget?C00860 C00860] |
− | ** [http://www.uniprot.org/uniprot/P45101 P45101]
| + | * PUBCHEM: |
− | ** [http://www.uniprot.org/uniprot/P45102 P45102]
| + | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=6950298 6950298] |
− | ** [http://www.uniprot.org/uniprot/Q9JUT0 Q9JUT0]
| + | {{#set: smiles=C1(NC=NC=1CC(CO)[N+])}} |
− | ** [http://www.uniprot.org/uniprot/Q58643 Q58643]
| + | {{#set: molecular weight=142.18 }} |
− | ** [http://www.uniprot.org/uniprot/O26663 O26663]
| + | {{#set: inchi key=InChIKey=ZQISRDCJNBUVMM-YFKPBYRVSA-O}} |
− | ** [http://www.uniprot.org/uniprot/P80886 P80886]
| + | {{#set: common name=histidinol}} |
− | ** [http://www.uniprot.org/uniprot/Q9PHY1 Q9PHY1]
| + | {{#set: common name=histidol|L-histidinol}} |
− | ** [http://www.uniprot.org/uniprot/Q9JUS9 Q9JUS9]
| + | {{#set: consumed by=RXN-8001}} |
− | ** [http://www.uniprot.org/uniprot/P80865 P80865]
| + | {{#set: produced by=HISTIDPHOS-RXN[CCO-CYTOSOL]-L-HISTIDINOL-P/WATER//HISTIDINOL/Pi.49.|HISTIDPHOS-RXN}} |
− | ** [http://www.uniprot.org/uniprot/Q9PHY0 Q9PHY0]
| + | {{#set: reversible reaction associated=HISTOLDEHYD-RXN}} |
− | ** [http://www.uniprot.org/uniprot/O67729 O67729]
| + | |
− | ** [http://www.uniprot.org/uniprot/O67546 O67546]
| + | |
− | ** [http://www.uniprot.org/uniprot/P53593 P53593]
| + | |
− | ** [http://www.uniprot.org/uniprot/P0AGE9 P0AGE9]
| + | |
− | ** [http://www.uniprot.org/uniprot/P0A836 P0A836]
| + | |
− | ** [http://www.uniprot.org/uniprot/O82662 O82662]
| + | |
− | {{#set: direction=REVERSIBLE}} | + | |
− | {{#set: ec number=EC-6.2.1.5}} | + | |
− | {{#set: common name=Succinate thiokinase|succinyl CoA synthesis}} | + | |
− | {{#set: gene associated=CHC_T00008602001_1|CHC_T00009212001_1}} | + | |
− | {{#set: in pathway=PWY-5913|P42-PWY|PWY-7384|PWY-5392|P23-PWY|PWY-6969|PWY-5537|PWY-6728|PWY-5538|PWY-5690|PWY66-398|TCA}} | + | |
− | {{#set: reconstruction category=orthology}} | + | |
− | {{#set: reconstruction tool=pantograph}} | + | |
− | {{#set: reconstruction source=galdieria.sulphuraria|a.taliana}} | + | |