Difference between revisions of "2.8.1.6-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=PHOSPHORIBULOSYL-FORMIMINO-AICAR-P PHOSPHORIBULOSYL-FORMIMINO-AICAR-P] == * smiles: ** C(OP(=O)...")
 
(One intermediate revision by the same user not shown)
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=PHOSPHORIBULOSYL-FORMIMINO-AICAR-P PHOSPHORIBULOSYL-FORMIMINO-AICAR-P] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=2.8.1.6-RXN 2.8.1.6-RXN] ==
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* smiles:
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* direction:
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** C(OP(=O)([O-])[O-])C(O)C(O)C(=O)CN=CNC2(N(C1(C(O)C(C(COP(=O)([O-])[O-])O1)O))C=NC(C(=O)N)=2)
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** LEFT-TO-RIGHT
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* inchi key:
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** InChIKey=BLKFNHOCHNCLII-GHVQHMAVSA-J
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* common name:
 
* common name:
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** phosphoribulosylformimino-AICAR-phosphate
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** biotin synthetase
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* molecular weight:
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* ec number:
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** 573.303   
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** [http://enzyme.expasy.org/EC/2.8.1.6 EC-2.8.1.6]
 
* Synonym(s):
 
* Synonym(s):
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** 5-[(5-phospho-1-deoxy-β-D-ribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide
 
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** N-(5'-phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide
 
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** phosphoribulosylformiminoAICAR-phosphate
 
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** phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribotide phosphate
 
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** phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate
 
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** PRFAR
 
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** N-(5'phospho-D-1'-ribulosylformimino)-5-amino-1-(5-phosphoribosyl)-4-imidazolecarboxamide
 
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** phosphoribulosylformimino-AICAR-P
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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* [[GLUTAMIDOTRANS-RXN]]
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* With identifiers:
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== Reaction(s) known to produce the compound ==
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** 2 [[S-ADENOSYLMETHIONINE]][c] '''+''' 1 [[DETHIOBIOTIN]][c] '''+''' 1 [[Sulfurated-Sulfur-Acceptors]][c] '''+''' 2 [[Reduced-2Fe-2S-Ferredoxins]][c] '''=>''' 2 [[Oxidized-2Fe-2S-Ferredoxins]][c] '''+''' 1 [[BIOTIN]][c] '''+''' 2 [[MET]][c] '''+''' 1 [[Unsulfurated-Sulfur-Acceptors]][c] '''+''' 2 [[CH33ADO]][c]
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* [[PRIBFAICARPISOM-RXN]]
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* With common name(s):
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== Reaction(s) of unknown directionality ==
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** 2 S-adenosyl-L-methionine[c] '''+''' 1 dethiobiotin[c] '''+''' 1 a sulfurated [sulfur carrier][c] '''+''' 2 a reduced [2Fe-2S] ferredoxin[c] '''=>''' 2 an oxidized [2Fe-2S] ferredoxin[c] '''+''' 1 biotin[c] '''+''' 2 L-methionine[c] '''+''' 1 an unsulfurated [sulfur carrier][c] '''+''' 2 5'-deoxyadenosine[c]
 +
 
 +
== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[CHC_T00009361001_1]]
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** Source: [[orthology-galdieria.sulphuraria]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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* Gene: [[CHC_T00009361001]]
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** Source: [[annotation-original_genome]]
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*** Assignment: AUTOMATED-NAME-MATCH
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== Pathways  ==
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* [[PWY0-1507]], biotin biosynthesis from 8-amino-7-oxononanoate I: [http://metacyc.org/META/NEW-IMAGE?object=PWY0-1507 PWY0-1507]
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** '''3''' reactions found over '''3''' reactions in the full pathway
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* [[PWY-7380]], biotin biosynthesis from 8-amino-7-oxononanoate II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7380 PWY-7380]
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** '''2''' reactions found over '''3''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[orthology]]
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** Source: [[orthology-galdieria.sulphuraria]]
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*** Tool: [[pantograph]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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*** Tool: [[pantograph]]
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* Category: [[annotation]]
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** Source: [[annotation-original_genome]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* LIGAND-CPD:
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* RHEA:
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** [http://www.genome.jp/dbget-bin/www_bget?C04916 C04916]
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=22060 22060]
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* CHEBI:
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* UNIPROT:
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=58525 58525]
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** [http://www.uniprot.org/uniprot/Q9JRW7 Q9JRW7]
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* BIGG : prlp
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** [http://www.uniprot.org/uniprot/Q9PLZ3 Q9PLZ3]
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* PUBCHEM:
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** [http://www.uniprot.org/uniprot/P53557 P53557]
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=45266672 45266672]
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** [http://www.uniprot.org/uniprot/O67104 O67104]
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* HMDB : HMDB12278
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** [http://www.uniprot.org/uniprot/P44987 P44987]
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{{#set: smiles=C(OP(=O)([O-])[O-])C(O)C(O)C(=O)CN=CNC2(N(C1(C(O)C(C(COP(=O)([O-])[O-])O1)O))C=NC(C(=O)N)=2)}}
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** [http://www.uniprot.org/uniprot/Q58692 Q58692]
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{{#set: inchi key=InChIKey=BLKFNHOCHNCLII-GHVQHMAVSA-J}}
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** [http://www.uniprot.org/uniprot/P0A506 P0A506]
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{{#set: common name=phosphoribulosylformimino-AICAR-phosphate}}
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** [http://www.uniprot.org/uniprot/Q9Z6L5 Q9Z6L5]
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{{#set: molecular weight=573.303    }}
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** [http://www.uniprot.org/uniprot/Q9JUE3 Q9JUE3]
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{{#set: common name=5-[(5-phospho-1-deoxy-β-D-ribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide|N-(5'-phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide|phosphoribulosylformiminoAICAR-phosphate|phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribotide phosphate|phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate|PRFAR|N-(5'phospho-D-1'-ribulosylformimino)-5-amino-1-(5-phosphoribosyl)-4-imidazolecarboxamide|phosphoribulosylformimino-AICAR-P}}
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** [http://www.uniprot.org/uniprot/P46396 P46396]
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{{#set: consumed by=GLUTAMIDOTRANS-RXN}}
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** [http://www.uniprot.org/uniprot/Q47862 Q47862]
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{{#set: produced by=PRIBFAICARPISOM-RXN}}
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** [http://www.uniprot.org/uniprot/P19206 P19206]
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** [http://www.uniprot.org/uniprot/P32451 P32451]
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** [http://www.uniprot.org/uniprot/P54967 P54967]
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** [http://www.uniprot.org/uniprot/P46715 P46715]
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** [http://www.uniprot.org/uniprot/P73538 P73538]
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** [http://www.uniprot.org/uniprot/P12996 P12996]
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** [http://www.uniprot.org/uniprot/O59778 O59778]
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* LIGAND-RXN:
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** [http://www.genome.jp/dbget-bin/www_bget?R01078 R01078]
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{{#set: direction=LEFT-TO-RIGHT}}
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{{#set: common name=biotin synthetase}}
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{{#set: ec number=EC-2.8.1.6}}
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{{#set: gene associated=CHC_T00009361001_1|CHC_T00009361001}}
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{{#set: in pathway=PWY0-1507|PWY-7380}}
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{{#set: reconstruction category=orthology|annotation}}
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{{#set: reconstruction source=orthology-galdieria.sulphuraria|annotation-original_genome|orthology-ectocarpus_siliculosus}}
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{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 16:54, 9 January 2019

Reaction 2.8.1.6-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • biotin synthetase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY0-1507, biotin biosynthesis from 8-amino-7-oxononanoate I: PWY0-1507
    • 3 reactions found over 3 reactions in the full pathway
  • PWY-7380, biotin biosynthesis from 8-amino-7-oxononanoate II: PWY-7380
    • 2 reactions found over 3 reactions in the full pathway

Reconstruction information

External links





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