Difference between revisions of "2-ISOPROPYLMALATESYN-RXN"

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[[Category:Reaction]]
 
[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-9632 RXN-9632] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=2-ISOPROPYLMALATESYN-RXN 2-ISOPROPYLMALATESYN-RXN] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
 
* common name:
 
* common name:
** 3-oxo-stearoyl-[acyl-carrier protein] synthase
+
** 2-isopropylmalate synthase
** Beta-ketoacyl synthase
+
 
* ec number:
 
* ec number:
** [http://enzyme.expasy.org/EC/2.3.1.41 EC-2.3.1.41]
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** [http://enzyme.expasy.org/EC/2.3.3.13 EC-2.3.3.13]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
** 1 [[Palmitoyl-ACPs]][c] '''+''' 1 [[MALONYL-COA]][c] '''+''' 1 [[PROTON]][c] '''=>''' 1 [[CARBON-DIOXIDE]][c] '''+''' 1 [[CO-A]][c] '''+''' 1 [[3-oxo-stearoyl-ACPs]][c]
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** 1 [[WATER]][c] '''+''' 1 [[ACETYL-COA]][c] '''+''' 1 [[2-KETO-ISOVALERATE]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[3-CARBOXY-3-HYDROXY-ISOCAPROATE]][c] '''+''' 1 [[CO-A]][c]
 
* With common name(s):
 
* With common name(s):
** 1 a palmitoyl-[acp][c] '''+''' 1 malonyl-CoA[c] '''+''' 1 H+[c] '''=>''' 1 CO2[c] '''+''' 1 coenzyme A[c] '''+''' 1 a 3-oxo-stearoyl-[acp][c]
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** 1 H2O[c] '''+''' 1 acetyl-CoA[c] '''+''' 1 3-methyl-2-oxobutanoate[c] '''=>''' 1 H+[c] '''+''' 1 (2S)-2-isopropylmalate[c] '''+''' 1 coenzyme A[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
* [[CHC_T00009465001]]
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* Gene: [[CHC_T00008989001_1]]
** ORIGINAL_GENOME
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** Source: [[orthology-galdieria.sulphuraria]]
***AUTOMATED-NAME-MATCH
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** Source: [[orthology-ectocarpus_siliculosus]]
 +
* Gene: [[CHC_T00009551001_1]]
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** Source: [[orthology-galdieria.sulphuraria]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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** Source: [[orthology-arabidopsis_thaliana]]
 +
* Gene: [[CHC_T00008989001]]
 +
** Source: [[annotation-original_genome]]
 +
*** Assignment: AUTOMATED-NAME-MATCH
 +
* Gene: [[CHC_T00009551001]]
 +
** Source: [[annotation-original_genome]]
 +
*** Assignment: AUTOMATED-NAME-MATCH
 
== Pathways  ==
 
== Pathways  ==
* [[PWY-5989]], stearate biosynthesis II (bacteria and plants): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5989 PWY-5989]
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* [[LEUSYN-PWY]], L-leucine biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=LEUSYN-PWY LEUSYN-PWY]
** '''6''' reactions found over '''6''' reactions in the full pathway
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** '''5''' reactions found over '''6''' reactions in the full pathway
 +
* [[PWY-6871]], 3-methylbutanol biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6871 PWY-6871]
 +
** '''6''' reactions found over '''7''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
* [[annotation]]:
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* Category: [[orthology]]
** [[pathwaytools]]:
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** Source: [[orthology-galdieria.sulphuraria]]
*** [[original_genome]]
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*** Tool: [[pantograph]]
 +
** Source: [[orthology-arabidopsis_thaliana]]
 +
*** Tool: [[pantograph]]
 +
** Source: [[orthology-ectocarpus_siliculosus]]
 +
*** Tool: [[pantograph]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-original_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 +
* RHEA:
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=21524 21524]
 +
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/P06208 P06208]
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** [http://www.uniprot.org/uniprot/Q58595 Q58595]
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** [http://www.uniprot.org/uniprot/P09151 P09151]
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** [http://www.uniprot.org/uniprot/Q9PLV9 Q9PLV9]
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** [http://www.uniprot.org/uniprot/Q9JUK6 Q9JUK6]
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** [http://www.uniprot.org/uniprot/Q58787 Q58787]
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** [http://www.uniprot.org/uniprot/P94565 P94565]
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** [http://www.uniprot.org/uniprot/Q9JP75 Q9JP75]
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** [http://www.uniprot.org/uniprot/Q02141 Q02141]
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** [http://www.uniprot.org/uniprot/P48575 P48575]
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** [http://www.uniprot.org/uniprot/O86511 O86511]
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* LIGAND-RXN:
 +
** [http://www.genome.jp/dbget-bin/www_bget?R01213 R01213]
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
{{#set: common name=3-oxo-stearoyl-[acyl-carrier protein] synthase}}
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{{#set: common name=2-isopropylmalate synthase}}
{{#set: common name=Beta-ketoacyl synthase}}
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{{#set: ec number=EC-2.3.3.13}}
{{#set: ec number=EC-2.3.1.41}}
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{{#set: gene associated=CHC_T00008989001_1|CHC_T00009551001_1|CHC_T00008989001|CHC_T00009551001}}
{{#set: gene associated=CHC_T00009465001}}
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{{#set: in pathway=LEUSYN-PWY|PWY-6871}}
{{#set: in pathway=PWY-5989}}
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{{#set: reconstruction category=orthology|annotation}}
{{#set: reconstruction category=annotation}}
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{{#set: reconstruction source=orthology-galdieria.sulphuraria|annotation-original_genome|orthology-arabidopsis_thaliana|orthology-ectocarpus_siliculosus}}
{{#set: reconstruction tool=pathwaytools}}
+
{{#set: reconstruction tool=pantograph|pathwaytools}}
{{#set: reconstruction source=original_genome}}
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Latest revision as of 18:00, 9 January 2019

Reaction 2-ISOPROPYLMALATESYN-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • 2-isopropylmalate synthase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • LEUSYN-PWY, L-leucine biosynthesis: LEUSYN-PWY
    • 5 reactions found over 6 reactions in the full pathway
  • PWY-6871, 3-methylbutanol biosynthesis (engineered): PWY-6871
    • 6 reactions found over 7 reactions in the full pathway

Reconstruction information

External links