Difference between revisions of "GLYOHMETRANS-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-1302 CPD-1302] == * smiles: ** CN1([CH](CNC2(N=C(NC(=O)C1=2)N))CNC3(=CC=C(C(=O)NC(C([O-])=O...")
 
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-1302 CPD-1302] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLYOHMETRANS-RXN GLYOHMETRANS-RXN] ==
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* smiles:
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* direction:
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** CN1([CH](CNC2(N=C(NC(=O)C1=2)N))CNC3(=CC=C(C(=O)NC(C([O-])=O)CCC(NC(C([O-])=O)CCC(NC(C([O-])=O)CCC(=O)[O-])=O)=O)C=C3))
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** REVERSIBLE
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* inchi key:
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* ec number:
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** InChIKey=HVRNKDVLFAVCJF-VJANTYMQSA-J
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** [http://enzyme.expasy.org/EC/2.1.2.1 EC-2.1.2.1]
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* common name:
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** N5-methyl--tetrahydropteroyl tri-L-glutamate
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* molecular weight:
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** 713.66   
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* Synonym(s):
 
* Synonym(s):
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** N5-methyl--H4PteGlu3
 
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** 5-methyltetrahydropteroyl tri-L-glutamate
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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* [[RXN-12730]]
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* With identifiers:
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== Reaction(s) known to produce the compound ==
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** 1 [[SER]][c] '''+''' 1 [[THF-GLU-N]][c] '''<=>''' 1 [[GLY]][c] '''+''' 1 [[METHYLENE-THF-GLU-N]][c] '''+''' 1 [[WATER]][c]
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== Reaction(s) of unknown directionality ==
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* With common name(s):
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* [[HOMOCYSMET-RXN]]
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** 1 L-serine[c] '''+''' 1 a tetrahydrofolate[c] '''<=>''' 1 glycine[c] '''+''' 1 a 5,10-methylene-tetrahydrofolate[c] '''+''' 1 H2O[c]
 +
 
 +
== Genes associated with this reaction  ==
 +
Genes have been associated with this reaction based on different elements listed below.
 +
* Gene: [[CHC_T00009460001_1]]
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** Source: [[orthology-galdieria.sulphuraria]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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* Gene: [[CHC_T00008323001_1]]
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** Source: [[orthology-galdieria.sulphuraria]]
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== Pathways  ==
 +
* [[GLYSYN-PWY]], glycine biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=GLYSYN-PWY GLYSYN-PWY]
 +
** '''1''' reactions found over '''1''' reactions in the full pathway
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* [[PWY-3841]], folate transformations II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3841 PWY-3841]
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** '''8''' reactions found over '''11''' reactions in the full pathway
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* [[PWY-5497]], purine nucleobases degradation II (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5497 PWY-5497]
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** '''6''' reactions found over '''24''' reactions in the full pathway
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* [[PWY-2161]], folate polyglutamylation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2161 PWY-2161]
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** '''5''' reactions found over '''5''' reactions in the full pathway
 +
* [[PWY-181]], photorespiration: [http://metacyc.org/META/NEW-IMAGE?object=PWY-181 PWY-181]
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** '''6''' reactions found over '''9''' reactions in the full pathway
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* [[1CMET2-PWY]], N10-formyl-tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=1CMET2-PWY 1CMET2-PWY]
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** '''7''' reactions found over '''9''' reactions in the full pathway
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* [[PWY-2201]], folate transformations I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2201 PWY-2201]
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** '''6''' reactions found over '''12''' reactions in the full pathway
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* [[PWY-3661-1]], glycine betaine degradation II (mammalian): [http://metacyc.org/META/NEW-IMAGE?object=PWY-3661-1 PWY-3661-1]
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** '''1''' reactions found over '''4''' reactions in the full pathway
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* [[PWY-1622]], formaldehyde assimilation I (serine pathway): [http://metacyc.org/META/NEW-IMAGE?object=PWY-1622 PWY-1622]
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** '''6''' reactions found over '''13''' reactions in the full pathway
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* [[PWY-3661]], glycine betaine degradation I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3661 PWY-3661]
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** '''2''' reactions found over '''7''' reactions in the full pathway
 +
== Reconstruction information  ==
 +
* Category: [[orthology]]
 +
** Source: [[orthology-galdieria.sulphuraria]]
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*** Tool: [[pantograph]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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*** Tool: [[pantograph]]
 
== External links  ==
 
== External links  ==
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* PUBCHEM:
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* RHEA:
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=49852302 49852302]
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=15481 15481]
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* CHEMSPIDER:
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* UNIPROT:
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** [http://www.chemspider.com/Chemical-Structure.17625689.html 17625689]
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** [http://www.uniprot.org/uniprot/P35623 P35623]
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* CHEBI:
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** [http://www.uniprot.org/uniprot/P34898 P34898]
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=58207 58207]
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** [http://www.uniprot.org/uniprot/P34899 P34899]
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* LIGAND-CPD:
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** [http://www.uniprot.org/uniprot/P34896 P34896]
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** [http://www.genome.jp/dbget-bin/www_bget?C04489 C04489]
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** [http://www.uniprot.org/uniprot/Q9CHW7 Q9CHW7]
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* HMDB : HMDB12177
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** [http://www.uniprot.org/uniprot/P34897 P34897]
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{{#set: smiles=CN1([CH](CNC2(N=C(NC(=O)C1=2)N))CNC3(=CC=C(C(=O)NC(C([O-])=O)CCC(NC(C([O-])=O)CCC(NC(C([O-])=O)CCC(=O)[O-])=O)=O)C=C3))}}
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** [http://www.uniprot.org/uniprot/P0A2E1 P0A2E1]
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{{#set: inchi key=InChIKey=HVRNKDVLFAVCJF-VJANTYMQSA-J}}
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** [http://www.uniprot.org/uniprot/O23254 O23254]
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{{#set: common name=N5-methyl--tetrahydropteroyl tri-L-glutamate}}
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** [http://www.uniprot.org/uniprot/O53441 O53441]
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{{#set: molecular weight=713.66    }}
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** [http://www.uniprot.org/uniprot/O08370 O08370]
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{{#set: common name=N5-methyl--H4PteGlu3|5-methyltetrahydropteroyl tri-L-glutamate}}
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** [http://www.uniprot.org/uniprot/P43844 P43844]
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{{#set: consumed by=RXN-12730}}
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** [http://www.uniprot.org/uniprot/Q58992 Q58992]
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{{#set: consumed or produced by=HOMOCYSMET-RXN}}
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** [http://www.uniprot.org/uniprot/O66776 O66776]
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** [http://www.uniprot.org/uniprot/Q9XAY7 Q9XAY7]
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** [http://www.uniprot.org/uniprot/P47634 P47634]
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** [http://www.uniprot.org/uniprot/Q9WZH9 Q9WZH9]
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** [http://www.uniprot.org/uniprot/P56089 P56089]
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** [http://www.uniprot.org/uniprot/O53615 O53615]
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** [http://www.uniprot.org/uniprot/O83349 O83349]
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** [http://www.uniprot.org/uniprot/Q9ZMP7 Q9ZMP7]
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** [http://www.uniprot.org/uniprot/O51547 O51547]
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** [http://www.uniprot.org/uniprot/O84439 O84439]
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** [http://www.uniprot.org/uniprot/P24531 P24531]
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** [http://www.uniprot.org/uniprot/P39148 P39148]
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** [http://www.uniprot.org/uniprot/P24060 P24060]
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** [http://www.uniprot.org/uniprot/P37292 P37292]
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** [http://www.uniprot.org/uniprot/P34895 P34895]
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** [http://www.uniprot.org/uniprot/P34894 P34894]
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** [http://www.uniprot.org/uniprot/P49357 P49357]
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** [http://www.uniprot.org/uniprot/P49358 P49358]
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** [http://www.uniprot.org/uniprot/P50433 P50433]
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** [http://www.uniprot.org/uniprot/P37291 P37291]
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** [http://www.uniprot.org/uniprot/P78011 P78011]
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** [http://www.uniprot.org/uniprot/P77962 P77962]
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** [http://www.uniprot.org/uniprot/Q9SVM4 Q9SVM4]
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** [http://www.uniprot.org/uniprot/Q9SUU0 Q9SUU0]
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** [http://www.uniprot.org/uniprot/Q9SZJ5 Q9SZJ5]
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** [http://www.uniprot.org/uniprot/O23984 O23984]
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** [http://www.uniprot.org/uniprot/P0A825 P0A825]
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** [http://www.uniprot.org/uniprot/P07511 P07511]
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* LIGAND-RXN:
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** [http://www.genome.jp/dbget-bin/www_bget?R00945 R00945]
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{{#set: direction=REVERSIBLE}}
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{{#set: ec number=EC-2.1.2.1}}
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{{#set: gene associated=CHC_T00009460001_1|CHC_T00008323001_1}}
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{{#set: in pathway=GLYSYN-PWY|PWY-3841|PWY-5497|PWY-2161|PWY-181|1CMET2-PWY|PWY-2201|PWY-3661-1|PWY-1622|PWY-3661}}
 +
{{#set: reconstruction category=orthology}}
 +
{{#set: reconstruction source=orthology-galdieria.sulphuraria|orthology-ectocarpus_siliculosus}}
 +
{{#set: reconstruction tool=pantograph}}

Latest revision as of 17:06, 9 January 2019

Reaction GLYOHMETRANS-RXN

  • direction:
    • REVERSIBLE
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 L-serine[c] + 1 a tetrahydrofolate[c] <=> 1 glycine[c] + 1 a 5,10-methylene-tetrahydrofolate[c] + 1 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • GLYSYN-PWY, glycine biosynthesis I: GLYSYN-PWY
    • 1 reactions found over 1 reactions in the full pathway
  • PWY-3841, folate transformations II: PWY-3841
    • 8 reactions found over 11 reactions in the full pathway
  • PWY-5497, purine nucleobases degradation II (anaerobic): PWY-5497
    • 6 reactions found over 24 reactions in the full pathway
  • PWY-2161, folate polyglutamylation: PWY-2161
    • 5 reactions found over 5 reactions in the full pathway
  • PWY-181, photorespiration: PWY-181
    • 6 reactions found over 9 reactions in the full pathway
  • 1CMET2-PWY, N10-formyl-tetrahydrofolate biosynthesis: 1CMET2-PWY
    • 7 reactions found over 9 reactions in the full pathway
  • PWY-2201, folate transformations I: PWY-2201
    • 6 reactions found over 12 reactions in the full pathway
  • PWY-3661-1, glycine betaine degradation II (mammalian): PWY-3661-1
    • 1 reactions found over 4 reactions in the full pathway
  • PWY-1622, formaldehyde assimilation I (serine pathway): PWY-1622
    • 6 reactions found over 13 reactions in the full pathway
  • PWY-3661, glycine betaine degradation I: PWY-3661
    • 2 reactions found over 7 reactions in the full pathway

Reconstruction information

External links




Retrieved from "http://gem-aureme.irisa.fr/ccrgem/index.php?title=GLYOHMETRANS-RXN&oldid=22701"