Difference between revisions of "AICARTRANSFORM-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=2.4.1.101-RXN 2.4.1.101-RXN] == * direction: ** LEFT-TO-RIGHT * ec number: ** [http://enzyme.expasy...")
 
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=2.4.1.101-RXN 2.4.1.101-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=AICARTRANSFORM-RXN AICARTRANSFORM-RXN] ==
 
* direction:
 
* direction:
** LEFT-TO-RIGHT
+
** REVERSIBLE
 +
* common name:
 +
** phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase)-IMP cyclohydrolase (inosinicase) (IMP synthetase) (ATIC)
 
* ec number:
 
* ec number:
** [http://enzyme.expasy.org/EC/2.4.1.101 EC-2.4.1.101]
+
** [http://enzyme.expasy.org/EC/2.1.2.3 EC-2.1.2.3]
 
* Synonym(s):
 
* Synonym(s):
 +
** 5-aminoimidazole-4-carboxamide ribonucleotide transformylase
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
** 1 [[UDP-N-ACETYL-D-GLUCOSAMINE]][c] '''+''' 1 [[Mannosyl5-N-Glycans]][c] '''=>''' 1 [[UDP]][c] '''+''' 1 [[Mannosyl5-N-acetyl-glucosamine2-R]][c] '''+''' 1 [[PROTON]][c]
+
** 1 [[AICAR]][c] '''+''' 1 [[FORMYL-THF-GLU-N]][c] '''<=>''' 1 [[PHOSPHORIBOSYL-FORMAMIDO-CARBOXAMIDE]][c] '''+''' 1 [[THF-GLU-N]][c]
 
* With common name(s):
 
* With common name(s):
** 1 UDP-N-acetyl-&alpha;-D-glucosamine[c] '''+''' 1 a (mannosyl)5-N-glycan[c] '''=>''' 1 UDP[c] '''+''' 1 a (mannosyl)5-(N-acetylglucosaminyl)-N-glycan[c] '''+''' 1 H+[c]
+
** 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide[c] '''+''' 1 an N10-formyl-tetrahydrofolate[c] '''<=>''' 1 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide[c] '''+''' 1 a tetrahydrofolate[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
* [[CHC_T00004649001_1]]
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* Gene: [[CHC_T00009056001_1]]
** [[pantograph]]-[[galdieria.sulphuraria]]
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** Source: [[orthology-galdieria.sulphuraria]]
* [[CHC_T00009095001_1]]
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** Source: [[orthology-ectocarpus_siliculosus]]
** [[pantograph]]-[[galdieria.sulphuraria]]
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* Gene: [[CHC_T00009056001]]
* [[CHC_T00008757001_1]]
+
** Source: [[annotation-original_genome]]
** [[pantograph]]-[[galdieria.sulphuraria]]
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*** Assignment: AUTOMATED-NAME-MATCH
 
== Pathways  ==
 
== Pathways  ==
* [[PWY-7426]], mannosyl-glycoprotein N-acetylglucosaminyltransferases: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7426 PWY-7426]
+
* [[PWY-6123]], inosine-5'-phosphate biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6123 PWY-6123]
** '''2''' reactions found over '''7''' reactions in the full pathway
+
** '''4''' reactions found over '''6''' reactions in the full pathway
 +
* [[PWY-6124]], inosine-5'-phosphate biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6124 PWY-6124]
 +
** '''5''' reactions found over '''5''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
* [[orthology]]:
+
* Category: [[orthology]]
** [[pantograph]]:
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** Source: [[orthology-galdieria.sulphuraria]]
*** [[galdieria.sulphuraria]]
+
*** Tool: [[pantograph]]
 +
** Source: [[orthology-ectocarpus_siliculosus]]
 +
*** Tool: [[pantograph]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-original_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=11456 11456]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=22192 22192]
 
* UNIPROT:
 
* UNIPROT:
** [http://www.uniprot.org/uniprot/P27115 P27115]
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** [http://www.uniprot.org/uniprot/P43852 P43852]
** [http://www.uniprot.org/uniprot/P27808 P27808]
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** [http://www.uniprot.org/uniprot/P12048 P12048]
** [http://www.uniprot.org/uniprot/Q09325 Q09325]
+
** [http://www.uniprot.org/uniprot/P31335 P31335]
** [http://www.uniprot.org/uniprot/Q9XGM8 Q9XGM8]
+
** [http://www.uniprot.org/uniprot/P26978 P26978]
** [http://www.uniprot.org/uniprot/Q21450 Q21450]
+
** [http://www.uniprot.org/uniprot/P15639 P15639]
** [http://www.uniprot.org/uniprot/Q11068 Q11068]
+
** [http://www.uniprot.org/uniprot/Q9PNY2 Q9PNY2]
** [http://www.uniprot.org/uniprot/Q9GPA3 Q9GPA3]
+
** [http://www.uniprot.org/uniprot/Q9JUQ8 Q9JUQ8]
** [http://www.uniprot.org/uniprot/P26572 P26572]
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** [http://www.uniprot.org/uniprot/P31939 P31939]
{{#set: direction=LEFT-TO-RIGHT}}
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** [http://www.uniprot.org/uniprot/Q59493 Q59493]
{{#set: ec number=EC-2.4.1.101}}
+
** [http://www.uniprot.org/uniprot/P38009 P38009]
{{#set: gene associated=CHC_T00004649001_1|CHC_T00009095001_1|CHC_T00008757001_1}}
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** [http://www.uniprot.org/uniprot/P54113 P54113]
{{#set: in pathway=PWY-7426}}
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** [http://www.uniprot.org/uniprot/O64767 O64767]
{{#set: reconstruction category=orthology}}
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** [http://www.uniprot.org/uniprot/O74928 O74928]
{{#set: reconstruction tool=pantograph}}
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* LIGAND-RXN:
{{#set: reconstruction source=galdieria.sulphuraria}}
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** [http://www.genome.jp/dbget-bin/www_bget?R04560 R04560]
 +
{{#set: direction=REVERSIBLE}}
 +
{{#set: common name=phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase)-IMP cyclohydrolase (inosinicase) (IMP synthetase) (ATIC)}}
 +
{{#set: ec number=EC-2.1.2.3}}
 +
{{#set: common name=5-aminoimidazole-4-carboxamide ribonucleotide transformylase}}
 +
{{#set: gene associated=CHC_T00009056001_1|CHC_T00009056001}}
 +
{{#set: in pathway=PWY-6123|PWY-6124}}
 +
{{#set: reconstruction category=orthology|annotation}}
 +
{{#set: reconstruction source=orthology-galdieria.sulphuraria|annotation-original_genome|orthology-ectocarpus_siliculosus}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 18:58, 9 January 2019

Reaction AICARTRANSFORM-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase)-IMP cyclohydrolase (inosinicase) (IMP synthetase) (ATIC)
  • ec number:
  • Synonym(s):
    • 5-aminoimidazole-4-carboxamide ribonucleotide transformylase

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide[c] + 1 an N10-formyl-tetrahydrofolate[c] <=> 1 5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide[c] + 1 a tetrahydrofolate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6123, inosine-5'-phosphate biosynthesis I: PWY-6123
    • 4 reactions found over 6 reactions in the full pathway
  • PWY-6124, inosine-5'-phosphate biosynthesis II: PWY-6124
    • 5 reactions found over 5 reactions in the full pathway

Reconstruction information

External links