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− | [[Category:Reaction]] | + | [[Category:Metabolite]] |
− | == Reaction [http://metacyc.org/META/NEW-IMAGE?object=METHYLENETHFDEHYDROG-NADP-RXN METHYLENETHFDEHYDROG-NADP-RXN] == | + | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=ETR-Quinones ETR-Quinones] == |
− | * direction:
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− | ** REVERSIBLE
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| * common name: | | * common name: |
− | ** Methylenetetrahydrofolate dehydrogenase | + | ** an electron-transfer quinone |
− | * ec number:
| + | |
− | ** [http://enzyme.expasy.org/EC/1.5.1.5 EC-1.5.1.5]
| + | |
| * Synonym(s): | | * Synonym(s): |
| | | |
− | == Reaction Formula == | + | == Reaction(s) known to consume the compound == |
− | * With identifiers:
| + | * [[RXN-11356]] |
− | ** 1 [[METHYLENE-THF-GLU-N]][c] '''+''' 1 [[NADP]][c] '''<=>''' 1 [[5-10-METHENYL-THF-GLU-N]][c] '''+''' 1 [[NADPH]][c]
| + | * [[RXN-11357]] |
− | * With common name(s):
| + | * [[RXN0-7230]] |
− | ** 1 a 5,10-methylene-tetrahydrofolate[c] '''+''' 1 NADP+[c] '''<=>''' 1 a 5,10-methenyltetrahydrofolate[c] '''+''' 1 NADPH[c]
| + | * [[RXN-14971]] |
− | | + | * [[RXN0-5259]] |
− | == Genes associated with this reaction == | + | == Reaction(s) known to produce the compound == |
− | Genes have been associated with this reaction based on different elements listed below.
| + | * [[RXN-15816]] |
− | * [[CHC_T00008670001_1]] | + | == Reaction(s) of unknown directionality == |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
| + | |
− | * [[CHC_T00008680001_1]] | + | |
− | ** [[pantograph]]-[[galdieria.sulphuraria]]
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− | * [[CHC_T00008680001]] | + | |
− | ** ORIGINAL_GENOME
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− | ***AUTOMATED-NAME-MATCH
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− | == Pathways ==
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− | * [[PWY-1722]], formate assimilation into 5,10-methylenetetrahydrofolate: [http://metacyc.org/META/NEW-IMAGE?object=PWY-1722 PWY-1722]
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− | ** '''3''' reactions found over '''3''' reactions in the full pathway
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− | * [[PWY-3841]], folate transformations II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3841 PWY-3841] | + | |
− | ** '''7''' reactions found over '''11''' reactions in the full pathway
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− | * [[1CMET2-PWY]], N10-formyl-tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=1CMET2-PWY 1CMET2-PWY]
| + | |
− | ** '''6''' reactions found over '''9''' reactions in the full pathway
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− | * [[CODH-PWY]], reductive acetyl coenzyme A pathway I (homoacetogenic bacteria): [http://metacyc.org/META/NEW-IMAGE?object=CODH-PWY CODH-PWY]
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− | ** '''4''' reactions found over '''9''' reactions in the full pathway
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− | * [[PWY-5497]], purine nucleobases degradation II (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5497 PWY-5497]
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− | ** '''7''' reactions found over '''24''' reactions in the full pathway
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− | * [[PWY-2201]], folate transformations I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2201 PWY-2201] | + | |
− | ** '''5''' reactions found over '''12''' reactions in the full pathway
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− | == Reconstruction information == | + | |
− | * [[orthology]]:
| + | |
− | ** [[pantograph]]:
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− | *** [[galdieria.sulphuraria]]
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− | * [[annotation]]:
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− | ** [[pathwaytools]]:
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− | *** [[original_genome]]
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| == External links == | | == External links == |
− | * RHEA:
| + | {{#set: common name=an electron-transfer quinone}} |
− | ** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=22812 22812]
| + | {{#set: consumed by=RXN-11356|RXN-11357|RXN0-7230|RXN-14971|RXN0-5259}} |
− | * LIGAND-RXN:
| + | {{#set: produced by=RXN-15816}} |
− | ** [http://www.genome.jp/dbget-bin/www_bget?R01220 R01220]
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− | * UNIPROT:
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− | ** [http://www.uniprot.org/uniprot/P09440 P09440]
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− | ** [http://www.uniprot.org/uniprot/P07245 P07245]
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− | ** [http://www.uniprot.org/uniprot/P11586 P11586]
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− | ** [http://www.uniprot.org/uniprot/P44313 P44313]
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− | ** [http://www.uniprot.org/uniprot/P47259 P47259]
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− | ** [http://www.uniprot.org/uniprot/P54382 P54382]
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− | ** [http://www.uniprot.org/uniprot/O67736 O67736]
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− | ** [http://www.uniprot.org/uniprot/Q9JWI9 Q9JWI9]
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− | ** [http://www.uniprot.org/uniprot/Q9PP68 Q9PP68]
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− | ** [http://www.uniprot.org/uniprot/P24186 P24186]
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− | ** [http://www.uniprot.org/uniprot/Q60006 Q60006]
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− | ** [http://www.uniprot.org/uniprot/Q27772 Q27772]
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− | ** [http://www.uniprot.org/uniprot/P51696 P51696]
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− | ** [http://www.uniprot.org/uniprot/O65269 O65269]
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− | ** [http://www.uniprot.org/uniprot/O65271 O65271]
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− | ** [http://www.uniprot.org/uniprot/O68031 O68031]
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− | ** [http://www.uniprot.org/uniprot/Q9ZTV0 Q9ZTV0]
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− | ** [http://www.uniprot.org/uniprot/Q9X7F6 Q9X7F6]
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− | {{#set: direction=REVERSIBLE}}
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− | {{#set: common name=Methylenetetrahydrofolate dehydrogenase}} | + | |
− | {{#set: ec number=EC-1.5.1.5}}
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− | {{#set: gene associated=CHC_T00008670001_1|CHC_T00008680001_1|CHC_T00008680001}} | + | |
− | {{#set: in pathway=PWY-1722|PWY-3841|1CMET2-PWY|CODH-PWY|PWY-5497|PWY-2201}}
| + | |
− | {{#set: reconstruction category=orthology}} | + | |
− | {{#set: reconstruction tool=pantograph}}
| + | |
− | {{#set: reconstruction source=galdieria.sulphuraria}}
| + | |
− | {{#set: reconstruction category=annotation}}
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− | {{#set: reconstruction tool=pathwaytools}}
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− | {{#set: reconstruction source=original_genome}}
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