Difference between revisions of "RXN-7719"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=ADENOSYL-HOMO-CYS ADENOSYL-HOMO-CYS] == * smiles: ** C(SCC3(C(O)C(O)C(N2(C1(N=CN=C(N)C=1N=C2)))...")
 
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=ADENOSYL-HOMO-CYS ADENOSYL-HOMO-CYS] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-7719 RXN-7719] ==
* smiles:
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* direction:
** C(SCC3(C(O)C(O)C(N2(C1(N=CN=C(N)C=1N=C2)))O3))CC(C([O-])=O)[N+]
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** REVERSIBLE
* inchi key:
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** InChIKey=ZJUKTBDSGOFHSH-WFMPWKQPSA-N
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* common name:
 
* common name:
** S-adenosyl-L-homocysteine
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** lipoamide dehydrogenase
* molecular weight:
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** dihydrolipoamide dehydrogenase
** 384.409   
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* ec number:
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** [http://enzyme.expasy.org/EC/1.8.1.4 EC-1.8.1.4]
 
* Synonym(s):
 
* Synonym(s):
** S-adenosylhomocysteine
 
** 2-S-adenosyl-L-homocysteine
 
** AdoHcy
 
** S-adenosyl-homocysteine
 
** adenosyl-homo-cys
 
** adenosylhomocysteine
 
** adenosylhomo-cys
 
** SAH
 
  
== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
* [[2.1.1.135-RXN]]
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* With identifiers:
== Reaction(s) known to produce the compound ==
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** 1 [[NAD]][c] '''+''' 1 [[BCAA-dehydrogenase-DH-lipoyl]][c] '''<=>''' 1 [[PROTON]][c] '''+''' 1 [[BCAA-dehydrogenase-lipoyl]][c] '''+''' 1 [[NADH]][c]
* [[ADOMET-DMK-METHYLTRANSFER-RXN]]
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* With common name(s):
* [[RXN-MG-PROTOPORPHYRIN-METHYLESTER-SYN]]
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** 1 NAD+[c] '''+''' 1 an [apo BCAA dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine[c] '''<=>''' 1 H+[c] '''+''' 1 an [apo BCAA dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] '''+''' 1 NADH[c]
* [[RXN-11757]]
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* [[RXN-11758]]
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== Genes associated with this reaction  ==
* [[2.1.1.114-RXN]]
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Genes have been associated with this reaction based on different elements listed below.
* [[RXN-9680]]
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* Gene: [[CHC_T00008441001]]
* [[RXN-14919]]
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** Source: [[annotation-original_genome]]
* [[RXN-14918]]
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*** Assignment: AUTOMATED-NAME-MATCH
* [[QUERCETIN-3-O-METHYLTRANSFERASE-RXN]]
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* Gene: [[CHC_T00010287001_1]]
* [[RXN-9287]]
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** Source: [[orthology-galdieria.sulphuraria]]
* [[RXN-9280]]
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** Source: [[orthology-ectocarpus_siliculosus]]
* [[RXN-14917]]
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* Gene: [[CHC_T00008584001_1]]
* [[RXN-9282]]
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** Source: [[orthology-galdieria.sulphuraria]]
* [[2.1.1.100-RXN]]
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** Source: [[orthology-ectocarpus_siliculosus]]
* [[2.1.1.16-RXN]]
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* Gene: [[CHC_T00008441001_1]]
* [[RXN-9361]]
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** Source: [[orthology-galdieria.sulphuraria]]
* [[HISTONE-LYSINE-N-METHYLTRANSFERASE-RXN]]
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** Source: [[orthology-ectocarpus_siliculosus]]
* [[RXN-9205]]
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* Gene: [[CHC_T00010287001]]
* [[2.1.1.64-RXN]]
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** Source: [[annotation-original_genome]]
* [[RXN-9220]]
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*** Assignment: AUTOMATED-NAME-MATCH
* [[RXN-7421]]
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* Gene: [[CHC_T00006349001_1]]
* [[RXN-9679]]
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** Source: [[orthology-galdieria.sulphuraria]]
* [[TRNA-GUANINE-N7--METHYLTRANSFERASE-RXN]]
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== Pathways  ==
* [[RXN-11046]]
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* [[PWY-5046]], 2-oxoisovalerate decarboxylation to isobutanoyl-CoA: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5046 PWY-5046]
* [[RXN-9281]]
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** '''3''' reactions found over '''3''' reactions in the full pathway
* [[RXN1G-2544]]
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== Reconstruction information  ==
* [[RXN-14177]]
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* Category: [[orthology]]
* [[RXN-11374]]
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** Source: [[orthology-galdieria.sulphuraria]]
* [[RXN-11373]]
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*** Tool: [[pantograph]]
* [[RXN-11370]]
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** Source: [[orthology-ectocarpus_siliculosus]]
* [[RXN-9363]]
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*** Tool: [[pantograph]]
* [[RXN-13403]]
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* Category: [[annotation]]
* [[CAFFEOYL-COA-O-METHYLTRANSFERASE-RXN]]
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** Source: [[annotation-original_genome]]
* [[RXN-9366]]
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*** Tool: [[pathwaytools]]
* [[RXN1G-3641]]
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* [[RXN-13405]]
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* [[RXN0-5144]]
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* [[RXN-2542]]
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* [[RXN-17366]]
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* [[RXN-13935]]
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* [[UROPORIIIMETHYLTRANSA-RXN]]
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* [[RXN-2562]]
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* [[RXN-9362]]
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* [[MRNA-GUANINE-N7--METHYLTRANSFERASE-RXN]]
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* [[2.1.1.127-RXN]]
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* [[RXN-11845]]
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* [[RXN0-5419]]
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* [[2.1.1.17-RXN]]
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* [[RXN-9235]]
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* [[RXN-9237]]
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* [[RXN-17896]]
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* [[2.1.1.77-RXN]]
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* [[2.1.1.79-RXN]]
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* [[RXN-11596]]
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* [[RXN-9191]]
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* [[RXN-7605]]
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* [[RXN-14326]]
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* [[RXN-2762]]
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* [[RXN-11598]]
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* [[RXN-8675]]
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* [[TOCOPHEROL-O-METHYLTRANSFERASE-RXN]]
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== Reaction(s) of unknown directionality ==
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* [[ADENOSYLHOMOCYSTEINASE-RXN]]
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== External links  ==
 
== External links  ==
* CAS : 979-92-0
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{{#set: direction=REVERSIBLE}}
* METABOLIGHTS : MTBLC57856
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{{#set: common name=lipoamide dehydrogenase}}
* PUBCHEM:
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{{#set: common name=dihydrolipoamide dehydrogenase}}
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=25246222 25246222]
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{{#set: ec number=EC-1.8.1.4}}
* HMDB : HMDB00939
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{{#set: gene associated=CHC_T00008441001|CHC_T00010287001_1|CHC_T00008584001_1|CHC_T00008441001_1|CHC_T00010287001|CHC_T00006349001_1}}
* LIGAND-CPD:
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{{#set: in pathway=PWY-5046}}
** [http://www.genome.jp/dbget-bin/www_bget?C00021 C00021]
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{{#set: reconstruction category=orthology|annotation}}
* CHEBI:
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{{#set: reconstruction source=orthology-galdieria.sulphuraria|annotation-original_genome|orthology-ectocarpus_siliculosus}}
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57856 57856]
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{{#set: reconstruction tool=pantograph|pathwaytools}}
* BIGG : ahcys
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{{#set: smiles=C(SCC3(C(O)C(O)C(N2(C1(N=CN=C(N)C=1N=C2)))O3))CC(C([O-])=O)[N+]}}
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{{#set: inchi key=InChIKey=ZJUKTBDSGOFHSH-WFMPWKQPSA-N}}
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{{#set: common name=S-adenosyl-L-homocysteine}}
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{{#set: molecular weight=384.409    }}
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{{#set: common name=S-adenosylhomocysteine|2-S-adenosyl-L-homocysteine|AdoHcy|S-adenosyl-homocysteine|adenosyl-homo-cys|adenosylhomocysteine|adenosylhomo-cys|SAH}}
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{{#set: consumed by=2.1.1.135-RXN}}
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{{#set: produced by=ADOMET-DMK-METHYLTRANSFER-RXN|RXN-MG-PROTOPORPHYRIN-METHYLESTER-SYN|RXN-11757|RXN-11758|2.1.1.114-RXN|RXN-9680|RXN-14919|RXN-14918|QUERCETIN-3-O-METHYLTRANSFERASE-RXN|RXN-9287|RXN-9280|RXN-14917|RXN-9282|2.1.1.100-RXN|2.1.1.16-RXN|RXN-9361|HISTONE-LYSINE-N-METHYLTRANSFERASE-RXN|RXN-9205|2.1.1.64-RXN|RXN-9220|RXN-7421|RXN-9679|TRNA-GUANINE-N7--METHYLTRANSFERASE-RXN|RXN-11046|RXN-9281|RXN1G-2544|RXN-14177|RXN-11374|RXN-11373|RXN-11370|RXN-9363|RXN-13403|CAFFEOYL-COA-O-METHYLTRANSFERASE-RXN|RXN-9366|RXN1G-3641|RXN-13405|RXN0-5144|RXN-2542|RXN-17366|RXN-13935|UROPORIIIMETHYLTRANSA-RXN|RXN-2562|RXN-9362|MRNA-GUANINE-N7--METHYLTRANSFERASE-RXN|2.1.1.127-RXN|RXN-11845|RXN0-5419|2.1.1.17-RXN|RXN-9235|RXN-9237|RXN-17896|2.1.1.77-RXN|2.1.1.79-RXN|RXN-11596|RXN-9191|RXN-7605|RXN-14326|RXN-2762|RXN-11598|RXN-8675|TOCOPHEROL-O-METHYLTRANSFERASE-RXN}}
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{{#set: consumed or produced by=ADENOSYLHOMOCYSTEINASE-RXN}}
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Latest revision as of 17:52, 9 January 2019

Reaction RXN-7719

  • direction:
    • REVERSIBLE
  • common name:
    • lipoamide dehydrogenase
    • dihydrolipoamide dehydrogenase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-5046, 2-oxoisovalerate decarboxylation to isobutanoyl-CoA: PWY-5046
    • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

External links