Difference between revisions of "DIHYDROFOLATESYNTH-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-14959 RXN-14959] == * direction: ** LEFT-TO-RIGHT * common name: ** Lipoate synthase * ec numbe...")
 
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN-14959 RXN-14959] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=DIHYDROFOLATESYNTH-RXN DIHYDROFOLATESYNTH-RXN] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
* common name:
 
** Lipoate synthase
 
 
* ec number:
 
* ec number:
** [http://enzyme.expasy.org/EC/2.8.1.8 EC-2.8.1.8]
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** [http://enzyme.expasy.org/EC/6.3.2.12 EC-6.3.2.12]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
** 2 [[Sulfurated-Sulfur-Acceptors]][c] '''+''' 1 [[a-2-oxoglutarate-dehydrogenase-E2-protei]][c] '''+''' 2 [[Reduced-2Fe-2S-Ferredoxins]][c] '''+''' 2 [[S-ADENOSYLMETHIONINE]][c] '''=>''' 2 [[CH33ADO]][c] '''+''' 2 [[Unsulfurated-Sulfur-Acceptors]][c] '''+''' 2 [[Oxidized-2Fe-2S-Ferredoxins]][c] '''+''' 2 [[MET]][c] '''+''' 1 [[Oxo-glutarate-dehydrogenase-lipoyl]][c]
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** 1 [[ATP]][c] '''+''' 1 [[7-8-DIHYDROPTEROATE]][c] '''+''' 1 [[GLT]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[DIHYDROFOLATE]][c] '''+''' 1 [[Pi]][c] '''+''' 1 [[ADP]][c]
 
* With common name(s):
 
* With common name(s):
** 2 a sulfurated [sulfur carrier][c] '''+''' 1 a [2-oxoglutarate-dehydrogenase E2 protein] N6-octanoyl-L-lysine[c] '''+''' 2 a reduced [2Fe-2S] ferredoxin[c] '''+''' 2 S-adenosyl-L-methionine[c] '''=>''' 2 5'-deoxyadenosine[c] '''+''' 2 an unsulfurated [sulfur carrier][c] '''+''' 2 an oxidized [2Fe-2S] ferredoxin[c] '''+''' 2 L-methionine[c] '''+''' 1 a [2-oxoglutarate dehydrogenase E2 protein] N6-lipoyl-L-lysine[c]
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** 1 ATP[c] '''+''' 1 7,8-dihydropteroate[c] '''+''' 1 L-glutamate[c] '''=>''' 1 H+[c] '''+''' 1 7,8-dihydrofolate monoglutamate[c] '''+''' 1 phosphate[c] '''+''' 1 ADP[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
* [[CHC_T00008509001_1]]
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* Gene: [[CHC_T00000400001_1]]
** [[pantograph]]-[[galdieria.sulphuraria]]
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** Source: [[orthology-galdieria.sulphuraria]]
* [[CHC_T00008509001]]
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** Source: [[orthology-ectocarpus_siliculosus]]
** ORIGINAL_GENOME
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***AUTOMATED-NAME-MATCH
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== Pathways  ==
 
== Pathways  ==
* [[PWY-7382]], lipoate biosynthesis and incorporation (yeast): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7382 PWY-7382]
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* [[PWY-6614]], tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6614 PWY-6614]
** '''4''' reactions found over '''7''' reactions in the full pathway
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** '''3''' reactions found over '''3''' reactions in the full pathway
 
== Reconstruction information  ==
 
== Reconstruction information  ==
* [[orthology]]:
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* Category: [[orthology]]
** [[pantograph]]:
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** Source: [[orthology-galdieria.sulphuraria]]
*** [[galdieria.sulphuraria]]
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*** Tool: [[pantograph]]
* [[annotation]]:
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** Source: [[orthology-ectocarpus_siliculosus]]
** [[pathwaytools]]:
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*** Tool: [[pantograph]]
*** [[original_genome]]
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== External links  ==
 
== External links  ==
 +
* RHEA:
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=23584 23584]
 +
* UNIPROT:
 +
** [http://www.uniprot.org/uniprot/Q9JVC6 Q9JVC6]
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** [http://www.uniprot.org/uniprot/P43775 P43775]
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** [http://www.uniprot.org/uniprot/Q9PNK6 Q9PNK6]
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** [http://www.uniprot.org/uniprot/Q50990 Q50990]
 +
** [http://www.uniprot.org/uniprot/P08192 P08192]
 +
* LIGAND-RXN:
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** [http://www.genome.jp/dbget-bin/www_bget?R02237 R02237]
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
{{#set: common name=Lipoate synthase}}
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{{#set: ec number=EC-6.3.2.12}}
{{#set: ec number=EC-2.8.1.8}}
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{{#set: gene associated=CHC_T00000400001_1}}
{{#set: gene associated=CHC_T00008509001_1|CHC_T00008509001}}
+
{{#set: in pathway=PWY-6614}}
{{#set: in pathway=PWY-7382}}
+
 
{{#set: reconstruction category=orthology}}
 
{{#set: reconstruction category=orthology}}
 +
{{#set: reconstruction source=orthology-galdieria.sulphuraria|orthology-ectocarpus_siliculosus}}
 
{{#set: reconstruction tool=pantograph}}
 
{{#set: reconstruction tool=pantograph}}
{{#set: reconstruction source=galdieria.sulphuraria}}
 
{{#set: reconstruction category=annotation}}
 
{{#set: reconstruction tool=pathwaytools}}
 
{{#set: reconstruction source=original_genome}}
 

Latest revision as of 15:37, 9 January 2019

Reaction DIHYDROFOLATESYNTH-RXN

  • direction:
    • LEFT-TO-RIGHT
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 ATP[c] + 1 7,8-dihydropteroate[c] + 1 L-glutamate[c] => 1 H+[c] + 1 7,8-dihydrofolate monoglutamate[c] + 1 phosphate[c] + 1 ADP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6614, tetrahydrofolate biosynthesis: PWY-6614
    • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

External links