Difference between revisions of "PYRUVDEH-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-12125 CPD-12125] == * smiles: ** CC(=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCC2(C...")
 
 
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-12125 CPD-12125] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=PYRUVDEH-RXN PYRUVDEH-RXN] ==
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* smiles:
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* direction:
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** CC(=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCC2(C(C)=C(O)C1(C=CC=CC=1C(O)=2)))C
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** LEFT-TO-RIGHT
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* inchi key:
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** InChIKey=VFGNPJRRTKMYKN-LJWNYQGCSA-N
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* common name:
 
* common name:
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** menaquinol-7
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** pyruvate dehydrogenase E1 alpha subunit, mitochondrial precursor
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* molecular weight:
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* ec number:
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** 651.026   
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** [http://enzyme.expasy.org/EC/1.2.1 EC-1.2.1]
 
* Synonym(s):
 
* Synonym(s):
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** menaquinol(7)
 
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** MKH2-7
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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== Reaction(s) known to produce the compound ==
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* With identifiers:
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* [[RXN-9191]]
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** 1 [[NAD]][c] '''+''' 1 [[PYRUVATE]][c] '''+''' 1 [[CO-A]][c] '''=>''' 1 [[NADH]][c] '''+''' 1 [[ACETYL-COA]][c] '''+''' 1 [[CARBON-DIOXIDE]][c]
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== Reaction(s) of unknown directionality ==
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* With common name(s):
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** 1 NAD+[c] '''+''' 1 pyruvate[c] '''+''' 1 coenzyme A[c] '''=>''' 1 NADH[c] '''+''' 1 acetyl-CoA[c] '''+''' 1 CO2[c]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[CHC_T00010287001_1]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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** Source: [[orthology-arabidopsis_thaliana]]
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** Source: [[orthology-arabidopsis_thaliana]]
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* Gene: [[CHC_T00008732001_1]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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** Source: [[orthology-arabidopsis_thaliana]]
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* Gene: [[CHC_T00008442001_1]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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** Source: [[orthology-arabidopsis_thaliana]]
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* Gene: [[CHC_T00008441001_1]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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** Source: [[orthology-arabidopsis_thaliana]]
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** Source: [[orthology-arabidopsis_thaliana]]
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* Gene: [[CHC_T00008732001]]
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** Source: [[annotation-original_genome]]
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*** Assignment: AUTOMATED-NAME-MATCH
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* Gene: [[CHC_T00007488001_1]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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** Source: [[orthology-arabidopsis_thaliana]]
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** Source: [[orthology-arabidopsis_thaliana]]
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* Gene: [[CHC_T00007380001_1]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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** Source: [[orthology-arabidopsis_thaliana]]
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** Source: [[orthology-arabidopsis_thaliana]]
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== Pathways  ==
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* [[PWY-7384]], anaerobic energy metabolism (invertebrates, mitochondrial): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7384 PWY-7384]
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** '''5''' reactions found over '''12''' reactions in the full pathway
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* [[PWY-5537]], pyruvate fermentation to acetate V: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5537 PWY-5537]
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** '''2''' reactions found over '''4''' reactions in the full pathway
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* [[GLYCOLYSIS-TCA-GLYOX-BYPASS]], superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass: [http://metacyc.org/META/NEW-IMAGE?object=GLYCOLYSIS-TCA-GLYOX-BYPASS GLYCOLYSIS-TCA-GLYOX-BYPASS]
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** '''3''' reactions found over '''5''' reactions in the full pathway
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* [[PWY-7218]], photosynthetic 3-hydroxybutanoate biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7218 PWY-7218]
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** '''7''' reactions found over '''10''' reactions in the full pathway
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* [[PWY-5482]], pyruvate fermentation to acetate II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5482 PWY-5482]
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** '''1''' reactions found over '''3''' reactions in the full pathway
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* [[PWY-6886]], 1-butanol autotrophic biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6886 PWY-6886]
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** '''8''' reactions found over '''11''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[orthology]]
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** Source: [[orthology-arabidopsis_thaliana]]
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*** Tool: [[pantograph]]
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** Source: [[orthology-ectocarpus_siliculosus]]
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*** Tool: [[pantograph]]
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* Category: [[annotation]]
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** Source: [[annotation-original_genome]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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* PUBCHEM:
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* RHEA:
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=447918 447918]
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=28042 28042]
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* CHEMSPIDER:
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* LIGAND-RXN:
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** [http://www.chemspider.com/Chemical-Structure.394875.html 394875]
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** [http://www.genome.jp/dbget-bin/www_bget?R00209 R00209]
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* CHEBI:
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{{#set: direction=LEFT-TO-RIGHT}}
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=64834 64834]
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{{#set: common name=pyruvate dehydrogenase E1 alpha subunit, mitochondrial precursor}}
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{{#set: smiles=CC(=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCC2(C(C)=C(O)C1(C=CC=CC=1C(O)=2)))C}}
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{{#set: ec number=EC-1.2.1}}
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{{#set: inchi key=InChIKey=VFGNPJRRTKMYKN-LJWNYQGCSA-N}}
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{{#set: gene associated=CHC_T00010287001_1|CHC_T00008732001_1|CHC_T00008442001_1|CHC_T00008441001_1|CHC_T00008732001|CHC_T00007488001_1|CHC_T00007380001_1}}
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{{#set: common name=menaquinol-7}}
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{{#set: in pathway=PWY-7384|PWY-5537|GLYCOLYSIS-TCA-GLYOX-BYPASS|PWY-7218|PWY-5482|PWY-6886}}
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{{#set: molecular weight=651.026    }}
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{{#set: reconstruction category=orthology|annotation}}
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{{#set: common name=menaquinol(7)|MKH2-7}}
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{{#set: reconstruction source=annotation-original_genome|orthology-arabidopsis_thaliana|orthology-ectocarpus_siliculosus}}
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{{#set: produced by=RXN-9191}}
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{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 15:59, 9 January 2019

Reaction PYRUVDEH-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • pyruvate dehydrogenase E1 alpha subunit, mitochondrial precursor
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 NAD+[c] + 1 pyruvate[c] + 1 coenzyme A[c] => 1 NADH[c] + 1 acetyl-CoA[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-7384, anaerobic energy metabolism (invertebrates, mitochondrial): PWY-7384
    • 5 reactions found over 12 reactions in the full pathway
  • PWY-5537, pyruvate fermentation to acetate V: PWY-5537
    • 2 reactions found over 4 reactions in the full pathway
  • GLYCOLYSIS-TCA-GLYOX-BYPASS, superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass: GLYCOLYSIS-TCA-GLYOX-BYPASS
    • 3 reactions found over 5 reactions in the full pathway
  • PWY-7218, photosynthetic 3-hydroxybutanoate biosynthesis (engineered): PWY-7218
    • 7 reactions found over 10 reactions in the full pathway
  • PWY-5482, pyruvate fermentation to acetate II: PWY-5482
    • 1 reactions found over 3 reactions in the full pathway
  • PWY-6886, 1-butanol autotrophic biosynthesis (engineered): PWY-6886
    • 8 reactions found over 11 reactions in the full pathway

Reconstruction information

External links





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