Difference between revisions of "METHYLENETHFDEHYDROG-NADP-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=FUMHYDR-RXN FUMHYDR-RXN] == * direction: ** REVERSIBLE * common name: ** fumarate hydratase precurs...")
 
 
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=FUMHYDR-RXN FUMHYDR-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=METHYLENETHFDEHYDROG-NADP-RXN METHYLENETHFDEHYDROG-NADP-RXN] ==
 
* direction:
 
* direction:
 
** REVERSIBLE
 
** REVERSIBLE
 
* common name:
 
* common name:
−
** fumarate hydratase precursor
+
** Methylenetetrahydrofolate dehydrogenase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/4.2.1.2 EC-4.2.1.2]
+
** [http://enzyme.expasy.org/EC/1.5.1.5 EC-1.5.1.5]
 
* Synonym(s):
 
* Synonym(s):
−
** fumarate hydration
 
−
** malate dehydration
 
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[MAL]][c] '''<=>''' 1 [[FUM]][c] '''+''' 1 [[WATER]][c]
+
** 1 [[METHYLENE-THF-GLU-N]][c] '''+''' 1 [[NADP]][c] '''<=>''' 1 [[5-10-METHENYL-THF-GLU-N]][c] '''+''' 1 [[NADPH]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 (S)-malate[c] '''<=>''' 1 fumarate[c] '''+''' 1 H2O[c]
+
** 1 a 5,10-methylene-tetrahydrofolate[c] '''+''' 1 NADP+[c] '''<=>''' 1 a 5,10-methenyltetrahydrofolate[c] '''+''' 1 NADPH[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* [[CHC_T00008951001_1]]
+
* Gene: [[CHC_T00008670001_1]]
−
** [[pantograph]]-[[galdieria.sulphuraria]]
+
** Source: [[orthology-galdieria.sulphuraria]]
−
** [[pantograph]]-[[a.taliana]]
+
* Gene: [[CHC_T00008680001_1]]
−
* [[CHC_T00008951001]]
+
** Source: [[orthology-galdieria.sulphuraria]]
−
** ORIGINAL_GENOME
+
** Source: [[orthology-ectocarpus_siliculosus]]
−
***AUTOMATED-NAME-MATCH
+
* Gene: [[CHC_T00008680001]]
 +
** Source: [[annotation-original_genome]]
 +
*** Assignment: AUTOMATED-NAME-MATCH
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-561]], superpathway of glyoxylate cycle and fatty acid degradation: [http://metacyc.org/META/NEW-IMAGE?object=PWY-561 PWY-561]
+
* [[CODH-PWY]], reductive acetyl coenzyme A pathway I (homoacetogenic bacteria): [http://metacyc.org/META/NEW-IMAGE?object=CODH-PWY CODH-PWY]
−
** '''5''' reactions found over '''8''' reactions in the full pathway
+
** '''4''' reactions found over '''9''' reactions in the full pathway
−
* [[PWY-5913]], partial TCA cycle (obligate autotrophs): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5913 PWY-5913]
+
* [[PWY-1722]], formate assimilation into 5,10-methylenetetrahydrofolate: [http://metacyc.org/META/NEW-IMAGE?object=PWY-1722 PWY-1722]
−
** '''10''' reactions found over '''11''' reactions in the full pathway
+
** '''3''' reactions found over '''3''' reactions in the full pathway
−
* [[P42-PWY]], incomplete reductive TCA cycle: [http://metacyc.org/META/NEW-IMAGE?object=P42-PWY P42-PWY]
+
* [[PWY-3841]], folate transformations II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3841 PWY-3841]
−
** '''3''' reactions found over '''7''' reactions in the full pathway
+
−
* [[PWY-7384]], anaerobic energy metabolism (invertebrates, mitochondrial): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7384 PWY-7384]
+
−
** '''5''' reactions found over '''12''' reactions in the full pathway
+
−
* [[PWY-5392]], reductive TCA cycle II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5392 PWY-5392]
+
−
** '''5''' reactions found over '''12''' reactions in the full pathway
+
−
* [[P23-PWY]], reductive TCA cycle I: [http://metacyc.org/META/NEW-IMAGE?object=P23-PWY P23-PWY]
+
−
** '''9''' reactions found over '''12''' reactions in the full pathway
+
−
* [[P105-PWY]], TCA cycle IV (2-oxoglutarate decarboxylase): [http://metacyc.org/META/NEW-IMAGE?object=P105-PWY P105-PWY]
+
 
** '''8''' reactions found over '''11''' reactions in the full pathway
 
** '''8''' reactions found over '''11''' reactions in the full pathway
−
* [[PWY-6969]], TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6969 PWY-6969]
+
* [[PWY-5497]], purine nucleobases degradation II (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5497 PWY-5497]
−
** '''8''' reactions found over '''12''' reactions in the full pathway
+
** '''6''' reactions found over '''24''' reactions in the full pathway
−
* [[FERMENTATION-PWY]], mixed acid fermentation: [http://metacyc.org/META/NEW-IMAGE?object=FERMENTATION-PWY FERMENTATION-PWY]
+
* [[1CMET2-PWY]], N10-formyl-tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=1CMET2-PWY 1CMET2-PWY]
−
** '''11''' reactions found over '''16''' reactions in the full pathway
+
−
* [[PWY-6728]], methylaspartate cycle: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6728 PWY-6728]
+
−
** '''9''' reactions found over '''18''' reactions in the full pathway
+
−
* [[REDCITCYC]], TCA cycle VIII (helicobacter): [http://metacyc.org/META/NEW-IMAGE?object=REDCITCYC REDCITCYC]
+
−
** '''5''' reactions found over '''9''' reactions in the full pathway
+
−
* [[PWY-7254]], TCA cycle VII (acetate-producers): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7254 PWY-7254]
+
 
** '''7''' reactions found over '''9''' reactions in the full pathway
 
** '''7''' reactions found over '''9''' reactions in the full pathway
−
* [[P108-PWY]], pyruvate fermentation to propanoate I: [http://metacyc.org/META/NEW-IMAGE?object=P108-PWY P108-PWY]
+
* [[PWY-2201]], folate transformations I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2201 PWY-2201]
−
** '''2''' reactions found over '''7''' reactions in the full pathway
+
** '''6''' reactions found over '''12''' reactions in the full pathway
−
* [[TCA]], TCA cycle I (prokaryotic): [http://metacyc.org/META/NEW-IMAGE?object=TCA TCA]
+
−
** '''9''' reactions found over '''10''' reactions in the full pathway
+
−
* [[PWY66-398]], TCA cycle III (animals): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-398 PWY66-398]
+
−
** '''10''' reactions found over '''11''' reactions in the full pathway
+
−
* [[PWY-5690]], TCA cycle II (plants and fungi): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5690 PWY-5690]
+
−
** '''9''' reactions found over '''9''' reactions in the full pathway
+
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* [[orthology]]:
+
* Category: [[orthology]]
−
** [[pantograph]]:
+
** Source: [[orthology-galdieria.sulphuraria]]
−
*** [[galdieria.sulphuraria]]
+
*** Tool: [[pantograph]]
−
*** [[a.taliana]]
+
** Source: [[orthology-ectocarpus_siliculosus]]
−
* [[annotation]]:
+
*** Tool: [[pantograph]]
−
** [[pathwaytools]]:
+
* Category: [[annotation]]
−
*** [[original_genome]]
+
** Source: [[annotation-original_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
 
* RHEA:
 
* RHEA:
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=12460 12460]
+
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=22812 22812]
−
* PIR:
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A47692 A47692]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A49760 A49760]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A64377 A64377]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A81281 A81281]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=A81807 A81807]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=B44511 B44511]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=B81862 B81862]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=E64461 E64461]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=E64685 E64685]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=H70896 H70896]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=H71462 H71462]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JC4293 JC4293]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=JC4982 JC4982]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=PA0062 PA0062]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S40448 S40448]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=S76348 S76348]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T00433 T00433]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T07374 T07374]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T41265 T41265]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T43727 T43727]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=T45269 T45269]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFBSC8 UFBSC8]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFBYM UFBYM]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFEC UFEC]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFECAQ UFECAQ]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFHUM UFHUM]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFPG UFPG]
+
−
** [http://pir.georgetown.edu/cgi-bin/nbrfget?uid=UFRT UFRT]
+
−
* LIGAND-RXN:
+
−
** [http://www.genome.jp/dbget-bin/www_bget?R01082 R01082]
+
 
* UNIPROT:
 
* UNIPROT:
−
** [http://www.uniprot.org/uniprot/Q04718 Q04718]
+
** [http://www.uniprot.org/uniprot/P09440 P09440]
−
** [http://www.uniprot.org/uniprot/Q58034 Q58034]
+
** [http://www.uniprot.org/uniprot/P07245 P07245]
−
** [http://www.uniprot.org/uniprot/O69294 O69294]
+
** [http://www.uniprot.org/uniprot/P11586 P11586]
−
** [http://www.uniprot.org/uniprot/Q9JTE3 Q9JTE3]
+
** [http://www.uniprot.org/uniprot/P44313 P44313]
−
** [http://www.uniprot.org/uniprot/P14407 P14407]
+
** [http://www.uniprot.org/uniprot/P47259 P47259]
−
** [http://www.uniprot.org/uniprot/Q9JTR0 Q9JTR0]
+
** [http://www.uniprot.org/uniprot/P54382 P54382]
−
** [http://www.uniprot.org/uniprot/Q58690 Q58690]
+
** [http://www.uniprot.org/uniprot/O67736 O67736]
−
** [http://www.uniprot.org/uniprot/O25883 O25883]
+
** [http://www.uniprot.org/uniprot/Q9JWI9 Q9JWI9]
−
** [http://www.uniprot.org/uniprot/O53446 O53446]
+
** [http://www.uniprot.org/uniprot/Q9PP68 Q9PP68]
−
** [http://www.uniprot.org/uniprot/O84863 O84863]
+
** [http://www.uniprot.org/uniprot/P24186 P24186]
−
** [http://www.uniprot.org/uniprot/Q51404 Q51404]
+
** [http://www.uniprot.org/uniprot/Q60006 Q60006]
−
** [http://www.uniprot.org/uniprot/Q7M4Z3 Q7M4Z3]
+
** [http://www.uniprot.org/uniprot/Q27772 Q27772]
−
** [http://www.uniprot.org/uniprot/P39461 P39461]
+
** [http://www.uniprot.org/uniprot/P51696 P51696]
−
** [http://www.uniprot.org/uniprot/Q55674 Q55674]
+
** [http://www.uniprot.org/uniprot/O65269 O65269]
−
** [http://www.uniprot.org/uniprot/P93033 P93033]
+
** [http://www.uniprot.org/uniprot/O65271 O65271]
−
** [http://www.uniprot.org/uniprot/Q43180 Q43180]
+
** [http://www.uniprot.org/uniprot/O68031 O68031]
−
** [http://www.uniprot.org/uniprot/O94552 O94552]
+
** [http://www.uniprot.org/uniprot/Q9ZTV0 Q9ZTV0]
−
** [http://www.uniprot.org/uniprot/O66271 O66271]
+
** [http://www.uniprot.org/uniprot/Q9X7F6 Q9X7F6]
−
** [http://www.uniprot.org/uniprot/Q60022 Q60022]
+
* LIGAND-RXN:
−
** [http://www.uniprot.org/uniprot/P07343 P07343]
+
** [http://www.genome.jp/dbget-bin/www_bget?R01220 R01220]
−
** [http://www.uniprot.org/uniprot/P08417 P08417]
+
−
** [http://www.uniprot.org/uniprot/P05042 P05042]
+
−
** [http://www.uniprot.org/uniprot/P0AC33 P0AC33]
+
−
** [http://www.uniprot.org/uniprot/P10173 P10173]
+
−
** [http://www.uniprot.org/uniprot/P14408 P14408]
+
 
{{#set: direction=REVERSIBLE}}
 
{{#set: direction=REVERSIBLE}}
−
{{#set: common name=fumarate hydratase precursor}}
+
{{#set: common name=Methylenetetrahydrofolate dehydrogenase}}
−
{{#set: ec number=EC-4.2.1.2}}
+
{{#set: ec number=EC-1.5.1.5}}
−
{{#set: common name=fumarate hydration|malate dehydration}}
+
{{#set: gene associated=CHC_T00008670001_1|CHC_T00008680001_1|CHC_T00008680001}}
−
{{#set: gene associated=CHC_T00008951001_1|CHC_T00008951001}}
+
{{#set: in pathway=CODH-PWY|PWY-1722|PWY-3841|PWY-5497|1CMET2-PWY|PWY-2201}}
−
{{#set: in pathway=PWY-561|PWY-5913|P42-PWY|PWY-7384|PWY-5392|P23-PWY|P105-PWY|PWY-6969|FERMENTATION-PWY|PWY-6728|REDCITCYC|PWY-7254|P108-PWY|TCA|PWY66-398|PWY-5690}}
+
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction category=orthology}}
+
{{#set: reconstruction source=orthology-galdieria.sulphuraria|annotation-original_genome|orthology-ectocarpus_siliculosus}}
−
{{#set: reconstruction tool=pantograph}}
+
{{#set: reconstruction tool=pantograph|pathwaytools}}
−
{{#set: reconstruction source=galdieria.sulphuraria|a.taliana}}
+
−
{{#set: reconstruction category=annotation}}
+
−
{{#set: reconstruction tool=pathwaytools}}
+
−
{{#set: reconstruction source=original_genome}}
+

Latest revision as of 17:20, 9 January 2019

Reaction METHYLENETHFDEHYDROG-NADP-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • Methylenetetrahydrofolate dehydrogenase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • CODH-PWY, reductive acetyl coenzyme A pathway I (homoacetogenic bacteria): CODH-PWY
    • 4 reactions found over 9 reactions in the full pathway
  • PWY-1722, formate assimilation into 5,10-methylenetetrahydrofolate: PWY-1722
    • 3 reactions found over 3 reactions in the full pathway
  • PWY-3841, folate transformations II: PWY-3841
    • 8 reactions found over 11 reactions in the full pathway
  • PWY-5497, purine nucleobases degradation II (anaerobic): PWY-5497
    • 6 reactions found over 24 reactions in the full pathway
  • 1CMET2-PWY, N10-formyl-tetrahydrofolate biosynthesis: 1CMET2-PWY
    • 7 reactions found over 9 reactions in the full pathway
  • PWY-2201, folate transformations I: PWY-2201
    • 6 reactions found over 12 reactions in the full pathway

Reconstruction information

External links





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