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− | [[Category:Metabolite]] | + | [[Category:Pathway]] |
− | == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=NADH NADH] == | + | == Pathway [http://metacyc.org/META/NEW-IMAGE?object=PWY-5188 PWY-5188] == |
− | * smiles:
| + | |
− | ** C1(=C(CC=CN1C5(OC(COP(=O)([O-])OP(=O)([O-])OCC2(OC(C(O)C(O)2)N4(C=NC3(C(N)=NC=NC=34))))C(O)C(O)5))C(N)=O)
| + | |
− | * inchi key:
| + | |
− | ** InChIKey=BOPGDPNILDQYTO-NNYOXOHSSA-L
| + | |
| * common name: | | * common name: |
− | ** NADH | + | ** tetrapyrrole biosynthesis I (from glutamate) |
− | * molecular weight: | + | * taxonomic range: |
− | ** 663.43 | + | ** [http://metacyc.org/META/NEW-IMAGE?object=TAX-33682 TAX-33682] |
| + | ** [http://metacyc.org/META/NEW-IMAGE?object=TAX-1117 TAX-1117] |
| + | ** [http://metacyc.org/META/NEW-IMAGE?object=TAX-1224 TAX-1224] |
| + | ** [http://metacyc.org/META/NEW-IMAGE?object=TAX-2157 TAX-2157] |
| + | ** [http://metacyc.org/META/NEW-IMAGE?object=TAX-3398 TAX-3398] |
| * Synonym(s): | | * Synonym(s): |
− | ** NADH2
| |
− | ** dihydrodiphosphopyridine nucleotide
| |
− | ** diphosphopyridine nucleotide reduced
| |
− | ** dihydronicotinamide adenine dinucleotide
| |
− | ** nicotinamide adenine dinucleotide reduced
| |
− | ** NAD-reduced
| |
− | ** NADH+H+
| |
− | ** DPNH
| |
− | ** β-NADH
| |
| | | |
− | == Reaction(s) known to consume the compound == | + | == Reaction(s) found == |
− | * [[RXN-11195]]
| + | '''6''' reactions found over '''6''' reactions in the full pathway |
− | * [[TRANS-RXN0-277]] | + | * [[GLURS-RXN]] |
− | * [[RXN-16632]]
| + | ** 2 associated gene(s): |
− | * [[RXN-10062]] | + | *** [[CHC_T00002361001_1]] |
− | * [[RXN-5424]] | + | *** [[CHC_T00008453001_1]] |
− | * [[RXN-11478]] | + | ** 2 reconstruction source(s) associated: |
− | * [[1.5.1.20-RXN]] | + | *** [[orthology-galdieria.sulphuraria]] |
− | * [[RXN-3661]] | + | *** [[orthology-ectocarpus_siliculosus]] |
− | * [[RXN3O-4113]] | + | * [[GLUTRNAREDUCT-RXN]] |
− | * [[DLACTDEHYDROGNAD-RXN]] | + | ** 2 associated gene(s): |
− | * [[RXN1G-488]] | + | *** [[CHC_T00009215001]] |
− | * [[RXN1G-526]] | + | *** [[CHC_T00009215001_1]] |
− | * [[RXN-9659]] | + | ** 3 reconstruction source(s) associated: |
− | * [[RXN-9658]] | + | *** [[orthology-galdieria.sulphuraria]] |
− | * [[RXN-10911]] | + | *** [[annotation-original_genome]] |
− | * [[TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN-CPD-10280/NAD//CPD-14282/NADH/PROTON.37.]] | + | *** [[orthology-ectocarpus_siliculosus]] |
− | * [[RXN-11482]] | + | * [[GSAAMINOTRANS-RXN]] |
− | * [[RXN-9635]] | + | ** 2 associated gene(s): |
− | * [[ENOYL-ACP-REDUCT-NADH-RXN]] | + | *** [[CHC_T00008868001_1]] |
− | * [[RXN-12754]] | + | *** [[CHC_T00008868001]] |
− | * [[TransportSeed_NADH]]
| + | ** 4 reconstruction source(s) associated: |
− | * [[RXN-10657]]
| + | *** [[orthology-galdieria.sulphuraria]] |
− | * [[RXN-12753]] | + | *** [[annotation-original_genome]] |
− | * [[RXN-7694]] | + | *** [[orthology-arabidopsis_thaliana]] |
− | * [[RXN0-4401]] | + | *** [[orthology-ectocarpus_siliculosus]] |
− | * [[1.1.1.8-RXN]] | + | * [[OHMETHYLBILANESYN-RXN]] |
− | * [[GLYCERATE-DEHYDROGENASE-RXN]] | + | ** 1 associated gene(s): |
− | * [[RXN-16628]] | + | *** [[CHC_T00003649001_1]] |
− | * [[RXN1F-152]] | + | ** 3 reconstruction source(s) associated: |
− | * [[RXN-16620]] | + | *** [[orthology-galdieria.sulphuraria]] |
− | * [[RXN-7700]] | + | *** [[orthology-arabidopsis_thaliana]] |
− | * [[RXN-16624]] | + | *** [[orthology-ectocarpus_siliculosus]] |
− | * [[FERRIC-CHELATE-REDUCTASE-RXN]] | + | * [[PORPHOBILSYNTH-RXN]] |
− | * [[RXN-7706]] | + | ** 2 associated gene(s): |
− | * [[1.5.1.20-RXN-5-METHYL-THF/NAD//METHYLENE-THF/NADH/PROTON.44.]] | + | *** [[CHC_T00008491001]] |
− | * [[TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN-CPD-10279/NAD//CPD-14281/NADH/PROTON.37.]] | + | *** [[CHC_T00008491001_1]] |
− | * [[RXN0-2145]] | + | ** 4 reconstruction source(s) associated: |
− | * [[RXN1G-395]] | + | *** [[orthology-galdieria.sulphuraria]] |
− | * [[BIOMASS-RXN]] | + | *** [[annotation-original_genome]] |
− | * [[CYTOCHROME-B5-REDUCTASE-RXN]] | + | *** [[orthology-arabidopsis_thaliana]] |
− | * [[1.6.5.4-RXN]] | + | *** [[orthology-ectocarpus_siliculosus]] |
− | * [[HOMOSERDEHYDROG-RXN-HOMO-SER/NAD//L-ASPARTATE-SEMIALDEHYDE/NADH/PROTON.51.]] | + | * [[UROGENIIISYN-RXN]] |
− | * [[RXN-9662]] | + | ** 1 associated gene(s): |
− | * [[RXN-9663]] | + | *** [[CHC_T00007253001_1]] |
− | * [[RXN-9660]] | + | ** 2 reconstruction source(s) associated: |
− | * [[RXN-9661]] | + | *** [[orthology-galdieria.sulphuraria]] |
− | * [[RXN-12559]] | + | *** [[orthology-ectocarpus_siliculosus]] |
− | * [[RXN-12558]] | + | == Reaction(s) not found == |
− | * [[RXN-12570]] | + | |
− | * [[RXN-9657]] | + | |
− | * [[RXN-13417]] | + | |
− | * [[RXN-10661]] | + | |
− | * [[RXN-9558]]
| + | |
− | * [[RXN-10781]]
| + | |
− | * [[RXN-12568-HEXANAL/CO-A/NAD//HEXANOYL-COA/NADH/PROTON.43.]]
| + | |
− | == Reaction(s) known to produce the compound ==
| + | |
− | * [[RXN-8001]] | + | |
− | * [[RXN-4142]] | + | |
− | * [[THREODEHYD-RXN]] | + | |
− | * [[RXN-14249]]
| + | |
− | * [[RXN-12490]]
| + | |
− | * [[RXN66-479]]
| + | |
− | * [[RXN-17794]]
| + | |
− | * [[RXN-17777]]
| + | |
− | * [[RXN66-476-CPD-388/NAD/WATER//CPD-8462/NADH/PROTON.40.]]
| + | |
− | * [[RXN-17790]] | + | |
− | * [[RXN66-476-CPD-14719/NAD/WATER//CPD-7830/NADH/PROTON.42.]] | + | |
− | * [[RXN-12705]] | + | |
− | * [[1.8.1.4-RXN]] | + | |
− | * [[RXN66-3]] | + | |
− | * [[RXN-17798]] | + | |
− | * [[PREPHENATEDEHYDROG-RXN]] | + | |
− | * [[RXN-905]] | + | |
− | * [[RXN-10715]] | + | |
− | * [[ISOCITRATE-DEHYDROGENASE-NAD+-RXN]] | + | |
− | * [[RXN-9758]] | + | |
− | * [[RXN-10912]] | + | |
− | * [[TransportSeed_NADH]] | + | |
− | * [[RXN-10917]] | + | |
− | * [[RXN-12507]] | + | |
− | * [[PYRUVDEH-RXN]] | + | |
− | * [[RXN-7682]] | + | |
− | * [[RXN-17808]] | + | |
− | * [[RXN-12750]] | + | |
− | * [[2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN]] | + | |
− | * [[RXN66-472]] | + | |
− | * [[PYRNUTRANSHYDROGEN-RXN]] | + | |
− | * [[RXN6666-5]] | + | |
− | * [[2OXOGLUTARATEDEH-RXN]] | + | |
− | * [[RXN-37]] | + | |
− | * [[RXN-7745]] | + | |
− | * [[OHACYL-COA-DEHYDROG-RXN]] | + | |
− | * [[RXN-3443]] | + | |
− | * [[RXN66-342]] | + | |
− | * [[RXN-1884]]
| + | |
− | * [[HISTALDEHYD-RXN]]
| + | |
− | * [[RXN-10698]]
| + | |
− | * [[RXN66-476]]
| + | |
− | * [[RXN-12693]]
| + | |
− | * [[RXN-17781]]
| + | |
− | * [[RXN-14271]]
| + | |
− | * [[RXN66-353]]
| + | |
− | * [[1.1.1.39-RXN]]
| + | |
− | * [[RXN-13158]]
| + | |
− | * [[UGD-RXN]]
| + | |
− | * [[RXN-10702]]
| + | |
− | * [[RXN-10703]]
| + | |
− | * [[1.2.1.25-RXN]]
| + | |
− | * [[RXN-10089]] | + | |
− | * [[RXN-12789]] | + | |
− | * [[ALDHDEHYDROG-RXN]] | + | |
− | * [[RXN0-1132]] | + | |
− | * [[RXN-9336]] | + | |
− | * [[RXN-17786]] | + | |
− | * [[2-KETO-ADIPATE-DEHYDROG-RXN]] | + | |
− | * [[3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN]] | + | |
− | * [[PYRIDOXAL-4-DEHYDROGENASE-RXN]]
| + | |
− | * [[R222-RXN]]
| + | |
− | * [[RXN-10780]]
| + | |
− | * [[RXN-13414]]
| + | |
− | * [[RXN66-478]]
| + | |
− | * [[RXN-11245]]
| + | |
− | == Reaction(s) of unknown directionality ==
| + | |
− | * [[MYO-INOSITOL-2-DEHYDROGENASE-RXN]] | + | |
− | * [[NADH-DEHYDROG-A-RXN]] | + | |
− | * [[RXN-7719]] | + | |
− | * [[PHENDEHYD-RXN]]
| + | |
− | * [[RXN0-901]]
| + | |
− | * [[D-THREO-ALDOSE-1-DEHYDROGENASE-RXN]]
| + | |
− | * [[RXN-7644]]
| + | |
− | * [[RXN-7716]]
| + | |
− | * [[LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN-CPD-348/NAD/WATER//PALMITATE/NADH/PROTON.41.]]
| + | |
− | * [[LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN-CPD-7873/NAD/WATER//STEARIC_ACID/NADH/PROTON.45.]] | + | |
− | * [[IMP-DEHYDROG-RXN]] | + | |
− | * [[RXN-14280]] | + | |
− | * [[GLYCOLATE-REDUCTASE-RXN]] | + | |
− | * [[HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN]] | + | |
− | * [[HEXADECANOL-DEHYDROGENASE-RXN]] | + | |
− | * [[RXN-16654]] | + | |
− | * [[NADH-DEHYDROGENASE-RXN]] | + | |
− | * [[RXN-8629]] | + | |
− | * [[RXN-12448]] | + | |
− | * [[RXN-11662]]
| + | |
− | * [[RXN-12303-PLASTOQUINONE-9/NADH/PROTON//CPD-12829/NAD.43.]] | + | |
− | * [[ALCOHOL-DEHYDROG-GENERIC-RXN]] | + | |
− | * [[ExchangeSeed_NADH]]
| + | |
− | * [[L-IDITOL-2-DEHYDROGENASE-RXN]]
| + | |
− | * [[RXN-10915]]
| + | |
− | * [[GLUTAMATE-DEHYDROGENASE-RXN]]
| + | |
− | * [[RETINOL-DEHYDROGENASE-RXN]]
| + | |
− | * [[HISTOLDEHYD-RXN]]
| + | |
− | * [[1.6.99.5-RXN-NADH/PLASTOQUINONE-9/PROTON//NAD/CPD-12829.43.]]
| + | |
− | * [[RXN-9510]] | + | |
− | * [[MALATE-DEH-RXN]] | + | |
− | * [[2KETO-3METHYLVALERATE-RXN]] | + | |
− | * [[RXN-7657]] | + | |
− | * [[ALCOHOL-DEHYDROG-RXN]] | + | |
− | * [[RXN-161]] | + | |
− | * [[RXN-1302]] | + | |
− | * [[RXN-7693]] | + | |
− | * [[RXN66-350]]
| + | |
− | * [[3-ISOPROPYLMALDEHYDROG-RXN]]
| + | |
− | * [[BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN]]
| + | |
− | * [[1.1.1.145-RXN]]
| + | |
− | * [[BADH-RXN]] | + | |
− | * [[CYSTINE-REDUCTASE-NADH-RXN]] | + | |
− | * [[RXN-16133]] | + | |
− | * [[GAPOXNPHOSPHN-RXN]]
| + | |
− | * [[PGLYCDEHYDROG-RXN]]
| + | |
− | * [[GCVMULTI-RXN-GLY/THF/NAD//METHYLENE-THF/AMMONIUM/CARBON-DIOXIDE/NADH.56.]]
| + | |
− | * [[BUTANAL-DEHYDROGENASE-RXN-BUTANAL/CO-A/NAD//BUTYRYL-COA/NADH/PROTON.42.]]
| + | |
− | * [[1.3.1.9-RXN]]
| + | |
− | * [[RXN0-276]]
| + | |
− | * [[RXN0-2044]]
| + | |
− | * [[RXN-14225]]
| + | |
− | * [[RXN-14224]]
| + | |
− | * [[RXN-13198]]
| + | |
− | * [[RXN-16655]]
| + | |
− | * [[RXN-16656]]
| + | |
− | * [[ACETALD-DEHYDROG-RXN]]
| + | |
− | * [[RXN-16653]]
| + | |
| == External links == | | == External links == |
− | * CAS : 58-68-4 | + | * ECOCYC: |
− | * METABOLIGHTS : MTBLC57945
| + | ** [http://metacyc.org/ECOLI/NEW-IMAGE?object=PWY-5188 PWY-5188] |
− | * PUBCHEM:
| + | {{#set: common name=tetrapyrrole biosynthesis I (from glutamate)}} |
− | ** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=21604869 21604869] | + | {{#set: taxonomic range=TAX-33682}} |
− | * HMDB : HMDB01487
| + | {{#set: taxonomic range=TAX-1117}} |
− | * LIGAND-CPD:
| + | {{#set: taxonomic range=TAX-1224}} |
− | ** [http://www.genome.jp/dbget-bin/www_bget?C00004 C00004]
| + | {{#set: taxonomic range=TAX-2157}} |
− | * CHEMSPIDER:
| + | {{#set: taxonomic range=TAX-3398}} |
− | ** [http://www.chemspider.com/Chemical-Structure.10239197.html 10239197]
| + | {{#set: reaction found=6}} |
− | * CHEBI:
| + | {{#set: total reaction=6}} |
− | ** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57945 57945]
| + | {{#set: completion rate=100.0}} |
− | * BIGG : nadh
| + | |
− | {{#set: smiles=C1(=C(CC=CN1C5(OC(COP(=O)([O-])OP(=O)([O-])OCC2(OC(C(O)C(O)2)N4(C=NC3(C(N)=NC=NC=34))))C(O)C(O)5))C(N)=O)}} | + | |
− | {{#set: inchi key=InChIKey=BOPGDPNILDQYTO-NNYOXOHSSA-L}} | + | |
− | {{#set: common name=NADH}} | + | |
− | {{#set: molecular weight=663.43 }} | + | |
− | {{#set: common name=NADH2|dihydrodiphosphopyridine nucleotide|diphosphopyridine nucleotide reduced|dihydronicotinamide adenine dinucleotide|nicotinamide adenine dinucleotide reduced|NAD-reduced|NADH+H+|DPNH|β-NADH}} | + | |
− | {{#set: consumed by=RXN-11195|TRANS-RXN0-277|RXN-16632|RXN-10062|RXN-5424|RXN-11478|1.5.1.20-RXN|RXN-3661|RXN3O-4113|DLACTDEHYDROGNAD-RXN|RXN1G-488|RXN1G-526|RXN-9659|RXN-9658|RXN-10911|TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN-CPD-10280/NAD//CPD-14282/NADH/PROTON.37.|RXN-11482|RXN-9635|ENOYL-ACP-REDUCT-NADH-RXN|RXN-12754|TransportSeed_NADH|RXN-10657|RXN-12753|RXN-7694|RXN0-4401|1.1.1.8-RXN|GLYCERATE-DEHYDROGENASE-RXN|RXN-16628|RXN1F-152|RXN-16620|RXN-7700|RXN-16624|FERRIC-CHELATE-REDUCTASE-RXN|RXN-7706|1.5.1.20-RXN-5-METHYL-THF/NAD//METHYLENE-THF/NADH/PROTON.44.|TRANS-2-ENOYL-COA-REDUCTASE-NAD+-RXN-CPD-10279/NAD//CPD-14281/NADH/PROTON.37.|RXN0-2145|RXN1G-395|BIOMASS-RXN|CYTOCHROME-B5-REDUCTASE-RXN|1.6.5.4-RXN|HOMOSERDEHYDROG-RXN-HOMO-SER/NAD//L-ASPARTATE-SEMIALDEHYDE/NADH/PROTON.51.|RXN-9662|RXN-9663|RXN-9660|RXN-9661|RXN-12559|RXN-12558|RXN-12570|RXN-9657|RXN-13417|RXN-10661|RXN-9558|RXN-10781|RXN-12568-HEXANAL/CO-A/NAD//HEXANOYL-COA/NADH/PROTON.43.}} | + | |
− | {{#set: produced by=RXN-8001|RXN-4142|THREODEHYD-RXN|RXN-14249|RXN-12490|RXN66-479|RXN-17794|RXN-17777|RXN66-476-CPD-388/NAD/WATER//CPD-8462/NADH/PROTON.40.|RXN-17790|RXN66-476-CPD-14719/NAD/WATER//CPD-7830/NADH/PROTON.42.|RXN-12705|1.8.1.4-RXN|RXN66-3|RXN-17798|PREPHENATEDEHYDROG-RXN|RXN-905|RXN-10715|ISOCITRATE-DEHYDROGENASE-NAD+-RXN|RXN-9758|RXN-10912|TransportSeed_NADH|RXN-10917|RXN-12507|PYRUVDEH-RXN|RXN-7682|RXN-17808|RXN-12750|2KETO-4METHYL-PENTANOATE-DEHYDROG-RXN|RXN66-472|PYRNUTRANSHYDROGEN-RXN|RXN6666-5|2OXOGLUTARATEDEH-RXN|RXN-37|RXN-7745|OHACYL-COA-DEHYDROG-RXN|RXN-3443|RXN66-342|RXN-1884|HISTALDEHYD-RXN|RXN-10698|RXN66-476|RXN-12693|RXN-17781|RXN-14271|RXN66-353|1.1.1.39-RXN|RXN-13158|UGD-RXN|RXN-10702|RXN-10703|1.2.1.25-RXN|RXN-10089|RXN-12789|ALDHDEHYDROG-RXN|RXN0-1132|RXN-9336|RXN-17786|2-KETO-ADIPATE-DEHYDROG-RXN|3-HYDROXYISOBUTYRATE-DEHYDROGENASE-RXN|PYRIDOXAL-4-DEHYDROGENASE-RXN|R222-RXN|RXN-10780|RXN-13414|RXN66-478|RXN-11245}} | + | |
− | {{#set: consumed or produced by=MYO-INOSITOL-2-DEHYDROGENASE-RXN|NADH-DEHYDROG-A-RXN|RXN-7719|PHENDEHYD-RXN|RXN0-901|D-THREO-ALDOSE-1-DEHYDROGENASE-RXN|RXN-7644|RXN-7716|LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN-CPD-348/NAD/WATER//PALMITATE/NADH/PROTON.41.|LONG-CHAIN-ALCOHOL-DEHYDROGENASE-RXN-CPD-7873/NAD/WATER//STEARIC_ACID/NADH/PROTON.45.|IMP-DEHYDROG-RXN|RXN-14280|GLYCOLATE-REDUCTASE-RXN|HYDROXYMETHYLGLUTARYL-COA-REDUCTASE-RXN|HEXADECANOL-DEHYDROGENASE-RXN|RXN-16654|NADH-DEHYDROGENASE-RXN|RXN-8629|RXN-12448|RXN-11662|RXN-12303-PLASTOQUINONE-9/NADH/PROTON//CPD-12829/NAD.43.|ALCOHOL-DEHYDROG-GENERIC-RXN|ExchangeSeed_NADH|L-IDITOL-2-DEHYDROGENASE-RXN|RXN-10915|GLUTAMATE-DEHYDROGENASE-RXN|RETINOL-DEHYDROGENASE-RXN|HISTOLDEHYD-RXN|1.6.99.5-RXN-NADH/PLASTOQUINONE-9/PROTON//NAD/CPD-12829.43.|RXN-9510|MALATE-DEH-RXN|2KETO-3METHYLVALERATE-RXN|RXN-7657|ALCOHOL-DEHYDROG-RXN|RXN-161|RXN-1302|RXN-7693|RXN66-350|3-ISOPROPYLMALDEHYDROG-RXN|BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN|1.1.1.145-RXN|BADH-RXN|CYSTINE-REDUCTASE-NADH-RXN|RXN-16133|GAPOXNPHOSPHN-RXN|PGLYCDEHYDROG-RXN|GCVMULTI-RXN-GLY/THF/NAD//METHYLENE-THF/AMMONIUM/CARBON-DIOXIDE/NADH.56.|BUTANAL-DEHYDROGENASE-RXN-BUTANAL/CO-A/NAD//BUTYRYL-COA/NADH/PROTON.42.|1.3.1.9-RXN|RXN0-276|RXN0-2044|RXN-14225|RXN-14224|RXN-13198|RXN-16655|RXN-16656|ACETALD-DEHYDROG-RXN|RXN-16653}} | + | |