Difference between revisions of "ACYLCOASYN-RXN"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=4-COUMARATE--COA-LIGASE-RXN 4-COUMARATE--COA-LIGASE-RXN] == * direction: ** LEFT-TO-RIGHT * ec numb...")
 
 
(2 intermediate revisions by the same user not shown)
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=4-COUMARATE--COA-LIGASE-RXN 4-COUMARATE--COA-LIGASE-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=ACYLCOASYN-RXN ACYLCOASYN-RXN] ==
 
* direction:
 
* direction:
 
** LEFT-TO-RIGHT
 
** LEFT-TO-RIGHT
 +
* common name:
 +
** 2,3,4-saturated fatty acyl-CoA synthetase
 +
** long-chain-fatty-acid-CoA ligase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/6.2.1.12 EC-6.2.1.12]
+
** [http://enzyme.expasy.org/EC/6.2.1.3 EC-6.2.1.3]
 
* Synonym(s):
 
* Synonym(s):
 +
** Acyl-activating enzyme
 +
** Fatty acid thiokinase (long-chain)
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[COUMARATE]][c] '''+''' 1 [[ATP]][c] '''+''' 1 [[CO-A]][c] '''=>''' 1 [[AMP]][c] '''+''' 1 [[PPI]][c] '''+''' 1 [[P-COUMAROYL-COA]][c]
+
** 1 [[ATP]][c] '''+''' 1 [[CPD66-39]][c] '''+''' 1 [[CO-A]][c] '''=>''' 1 [[Saturated-Fatty-Acyl-CoA]][c] '''+''' 1 [[PPI]][c] '''+''' 1 [[AMP]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 4-coumarate[c] '''+''' 1 ATP[c] '''+''' 1 coenzyme A[c] '''=>''' 1 AMP[c] '''+''' 1 diphosphate[c] '''+''' 1 4-coumaroyl-CoA[c]
+
** 1 ATP[c] '''+''' 1 a 2,3,4-saturated fatty acid[c] '''+''' 1 coenzyme A[c] '''=>''' 1 a 2,3,4-saturated fatty acyl CoA[c] '''+''' 1 diphosphate[c] '''+''' 1 AMP[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* [[CHC_T00008472001_1]]
+
* Gene: [[CHC_T00009428001_1]]
−
** [[pantograph]]-[[a.taliana]]
+
** Source: [[orthology-galdieria.sulphuraria]]
−
* [[CHC_T00008160001_1]]
+
** Source: [[orthology-ectocarpus_siliculosus]]
−
** [[pantograph]]-[[a.taliana]]
+
* Gene: [[CHC_T00008811001]]
 +
** Source: [[annotation-original_genome]]
 +
*** Assignment: AUTOMATED-NAME-MATCH
 +
* Gene: [[CHC_T00008811001_1]]
 +
** Source: [[orthology-galdieria.sulphuraria]]
 +
* Gene: [[CHC_T00008160001_1]]
 +
** Source: [[orthology-galdieria.sulphuraria]]
 +
* Gene: [[CHC_T00008500001_1]]
 +
** Source: [[orthology-galdieria.sulphuraria]]
 +
** Source: [[orthology-ectocarpus_siliculosus]]
 +
* Gene: [[CHC_T00009428001]]
 +
** Source: [[annotation-original_genome]]
 +
*** Assignment: AUTOMATED-NAME-MATCH
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-6920]], 6-gingerol analog biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6920 PWY-6920]
+
* [[PWY-5136]], fatty acid β-oxidation II (peroxisome): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5136 PWY-5136]
−
** '''3''' reactions found over '''6''' reactions in the full pathway
+
** '''5''' reactions found over '''5''' reactions in the full pathway
−
* [[PWY-6435]], 4-hydroxybenzoate biosynthesis V: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6435 PWY-6435]
+
* [[PWY-7288]], fatty acid β-oxidation (peroxisome, yeast): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7288 PWY-7288]
−
** '''4''' reactions found over '''5''' reactions in the full pathway
+
** '''3''' reactions found over '''5''' reactions in the full pathway
−
* [[PWY1F-FLAVSYN]], flavonoid biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY1F-FLAVSYN PWY1F-FLAVSYN]
+
* [[FAO-PWY]], fatty acid β-oxidation I: [http://metacyc.org/META/NEW-IMAGE?object=FAO-PWY FAO-PWY]
−
** '''4''' reactions found over '''5''' reactions in the full pathway
+
** '''7''' reactions found over '''7''' reactions in the full pathway
−
* [[PWY-7046]], 4-coumarate degradation (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7046 PWY-7046]
+
* [[PWY66-391]], fatty acid β-oxidation VI (peroxisome): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-391 PWY66-391]
−
** '''2''' reactions found over '''6''' reactions in the full pathway
+
** '''5''' reactions found over '''7''' reactions in the full pathway
−
* [[PWY-6982]], umbelliferone biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6982 PWY-6982]
+
−
** '''1''' reactions found over '''3''' reactions in the full pathway
+
−
* [[PWY-7397]], naringenin biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7397 PWY-7397]
+
−
** '''3''' reactions found over '''4''' reactions in the full pathway
+
−
* [[PWY-6320]], phaselate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6320 PWY-6320]
+
−
** '''1''' reactions found over '''5''' reactions in the full pathway
+
−
* [[PWY-7398]], coumarins biosynthesis (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7398 PWY-7398]
+
−
** '''3''' reactions found over '''13''' reactions in the full pathway
+
−
* [[PWY-5754]], 4-hydroxybenzoate biosynthesis I (eukaryotes): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5754 PWY-5754]
+
−
** '''2''' reactions found over '''6''' reactions in the full pathway
+
−
* [[PWY-5135]], xanthohumol biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5135 PWY-5135]
+
−
** '''2''' reactions found over '''4''' reactions in the full pathway
+
−
* [[PWY-361]], phenylpropanoid biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-361 PWY-361]
+
−
** '''6''' reactions found over '''15''' reactions in the full pathway
+
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* [[orthology]]:
+
* Category: [[orthology]]
−
** [[pantograph]]:
+
** Source: [[orthology-galdieria.sulphuraria]]
−
*** [[a.taliana]]
+
*** Tool: [[pantograph]]
 +
** Source: [[orthology-ectocarpus_siliculosus]]
 +
*** Tool: [[pantograph]]
 +
* Category: [[annotation]]
 +
** Source: [[annotation-original_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
−
* RHEA:
 
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=19641 19641]
 
−
* LIGAND-RXN:
 
−
** [http://www.genome.jp/dbget-bin/www_bget?R01616 R01616]
 
 
* UNIPROT:
 
* UNIPROT:
−
** [http://www.uniprot.org/uniprot/P31684 P31684]
+
** [http://www.uniprot.org/uniprot/P18163 P18163]
−
** [http://www.uniprot.org/uniprot/P31685 P31685]
+
** [http://www.uniprot.org/uniprot/P39518 P39518]
−
** [http://www.uniprot.org/uniprot/Q9SWH8 Q9SWH8]
+
** [http://www.uniprot.org/uniprot/O51162 O51162]
−
** [http://www.uniprot.org/uniprot/Q9SWH7 Q9SWH7]
+
** [http://www.uniprot.org/uniprot/P39002 P39002]
−
** [http://www.uniprot.org/uniprot/P17814 P17814]
+
** [http://www.uniprot.org/uniprot/Q9RYK3 Q9RYK3]
−
** [http://www.uniprot.org/uniprot/P31687 P31687]
+
** [http://www.uniprot.org/uniprot/Q10776 Q10776]
−
** [http://www.uniprot.org/uniprot/Q8S5C2 Q8S5C2]
+
** [http://www.uniprot.org/uniprot/O83181 O83181]
−
** [http://www.uniprot.org/uniprot/P14912 P14912]
+
** [http://www.uniprot.org/uniprot/Q9RTR4 Q9RTR4]
−
** [http://www.uniprot.org/uniprot/P14913 P14913]
+
** [http://www.uniprot.org/uniprot/P94547 P94547]
−
** [http://www.uniprot.org/uniprot/P31686 P31686]
+
** [http://www.uniprot.org/uniprot/Q9YCF0 Q9YCF0]
−
** [http://www.uniprot.org/uniprot/Q42524 Q42524]
+
** [http://www.uniprot.org/uniprot/Q9CHR0 Q9CHR0]
−
** [http://www.uniprot.org/uniprot/Q42943 Q42943]
+
** [http://www.uniprot.org/uniprot/Q9JTK0 Q9JTK0]
−
** [http://www.uniprot.org/uniprot/Q42982 Q42982]
+
** [http://www.uniprot.org/uniprot/P44446 P44446]
−
** [http://www.uniprot.org/uniprot/P93360 P93360]
+
** [http://www.uniprot.org/uniprot/O30039 O30039]
−
** [http://www.uniprot.org/uniprot/P93361 P93361]
+
** [http://www.uniprot.org/uniprot/O51539 O51539]
−
** [http://www.uniprot.org/uniprot/O24146 O24146]
+
** [http://www.uniprot.org/uniprot/Q9JYJ7 Q9JYJ7]
−
** [http://www.uniprot.org/uniprot/O48868 O48868]
+
** [http://www.uniprot.org/uniprot/P33121 P33121]
−
** [http://www.uniprot.org/uniprot/O48869 O48869]
+
** [http://www.uniprot.org/uniprot/P33124 P33124]
−
** [http://www.uniprot.org/uniprot/O81139 O81139]
+
** [http://www.uniprot.org/uniprot/P30624 P30624]
−
** [http://www.uniprot.org/uniprot/O81140 O81140]
+
** [http://www.uniprot.org/uniprot/Q02602 Q02602]
−
** [http://www.uniprot.org/uniprot/P41636 P41636]
+
** [http://www.uniprot.org/uniprot/P69451 P69451]
 +
** [http://www.uniprot.org/uniprot/P69452 P69452]
 +
** [http://www.uniprot.org/uniprot/Q8JZR0 Q8JZR0]
 +
** [http://www.uniprot.org/uniprot/P47912 P47912]
 +
** [http://www.uniprot.org/uniprot/P73004 P73004]
 +
** [http://www.uniprot.org/uniprot/O81614 O81614]
 +
** [http://www.uniprot.org/uniprot/O15840 O15840]
 +
** [http://www.uniprot.org/uniprot/Q96537 Q96537]
 +
** [http://www.uniprot.org/uniprot/Q96538 Q96538]
 +
** [http://www.uniprot.org/uniprot/Q96338 Q96338]
 +
** [http://www.uniprot.org/uniprot/Q9T009 Q9T009]
 +
** [http://www.uniprot.org/uniprot/Q9T0A0 Q9T0A0]
 +
** [http://www.uniprot.org/uniprot/Q9ZBW6 Q9ZBW6]
 +
** [http://www.uniprot.org/uniprot/Q9X7Y5 Q9X7Y5]
 +
** [http://www.uniprot.org/uniprot/Q9X7Z0 Q9X7Z0]
 +
** [http://www.uniprot.org/uniprot/O60135 O60135]
 
{{#set: direction=LEFT-TO-RIGHT}}
 
{{#set: direction=LEFT-TO-RIGHT}}
−
{{#set: ec number=EC-6.2.1.12}}
+
{{#set: common name=2,3,4-saturated fatty acyl-CoA synthetase}}
−
{{#set: gene associated=CHC_T00008472001_1|CHC_T00008160001_1}}
+
{{#set: common name=long-chain-fatty-acid-CoA ligase}}
−
{{#set: in pathway=PWY-6920|PWY-6435|PWY1F-FLAVSYN|PWY-7046|PWY-6982|PWY-7397|PWY-6320|PWY-7398|PWY-5754|PWY-5135|PWY-361}}
+
{{#set: ec number=EC-6.2.1.3}}
−
{{#set: reconstruction category=orthology}}
+
{{#set: common name=Acyl-activating enzyme|Fatty acid thiokinase (long-chain)}}
−
{{#set: reconstruction tool=pantograph}}
+
{{#set: gene associated=CHC_T00009428001_1|CHC_T00008811001|CHC_T00008811001_1|CHC_T00008160001_1|CHC_T00008500001_1|CHC_T00009428001}}
−
{{#set: reconstruction source=a.taliana}}
+
{{#set: in pathway=PWY-5136|PWY-7288|FAO-PWY|PWY66-391}}
 +
{{#set: reconstruction category=orthology|annotation}}
 +
{{#set: reconstruction source=orthology-galdieria.sulphuraria|annotation-original_genome|orthology-ectocarpus_siliculosus}}
 +
{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 16:24, 9 January 2019

Reaction ACYLCOASYN-RXN

  • direction:
    • LEFT-TO-RIGHT
  • common name:
    • 2,3,4-saturated fatty acyl-CoA synthetase
    • long-chain-fatty-acid-CoA ligase
  • ec number:
  • Synonym(s):
    • Acyl-activating enzyme
    • Fatty acid thiokinase (long-chain)

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 ATP[c] + 1 a 2,3,4-saturated fatty acid[c] + 1 coenzyme A[c] => 1 a 2,3,4-saturated fatty acyl CoA[c] + 1 diphosphate[c] + 1 AMP[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-5136, fatty acid β-oxidation II (peroxisome): PWY-5136
    • 5 reactions found over 5 reactions in the full pathway
  • PWY-7288, fatty acid β-oxidation (peroxisome, yeast): PWY-7288
    • 3 reactions found over 5 reactions in the full pathway
  • FAO-PWY, fatty acid β-oxidation I: FAO-PWY
    • 7 reactions found over 7 reactions in the full pathway
  • PWY66-391, fatty acid β-oxidation VI (peroxisome): PWY66-391
    • 5 reactions found over 7 reactions in the full pathway

Reconstruction information

External links






Retrieved from "http://gem-aureme.irisa.fr/ccrgem/index.php?title=ACYLCOASYN-RXN&oldid=20252"