Difference between revisions of "RXN0-1147"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=METHENYLTHFCYCLOHYDRO-RXN METHENYLTHFCYCLOHYDRO-RXN] == * direction: ** REVERSIBLE * ec number: **...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN0-1147 RXN0-1147] == * direction: ** REVERSIBLE * common name: ** 2-oxoglutarate dehydrogenase,...")
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[[Category:Reaction]]
 
[[Category:Reaction]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=METHENYLTHFCYCLOHYDRO-RXN METHENYLTHFCYCLOHYDRO-RXN] ==
+
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=RXN0-1147 RXN0-1147] ==
 
* direction:
 
* direction:
 
** REVERSIBLE
 
** REVERSIBLE
 +
* common name:
 +
** 2-oxoglutarate dehydrogenase, E1 component
 +
** dihydrolipoamide dehydrogenase
 
* ec number:
 
* ec number:
−
** [http://enzyme.expasy.org/EC/3.5.4.9 EC-3.5.4.9]
+
** [http://enzyme.expasy.org/EC/2.3.1.61 EC-2.3.1.61]
 
* Synonym(s):
 
* Synonym(s):
  
 
== Reaction Formula ==
 
== Reaction Formula ==
 
* With identifiers:
 
* With identifiers:
−
** 1 [[5-10-METHENYL-THF-GLU-N]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[PROTON]][c] '''+''' 1 [[FORMYL-THF-GLU-N]][c]
+
** 1 [[Oxo-glutarate-dehydrogenase-DH-lipoyl]][c] '''+''' 1 [[SUC-COA]][c] '''<=>''' 1 [[CO-A]][c] '''+''' 1 [[Oxo-glutarate-dehydro-suc-DH-lipoyl]][c]
 
* With common name(s):
 
* With common name(s):
−
** 1 a 5,10-methenyltetrahydrofolate[c] '''+''' 1 H2O[c] '''<=>''' 1 H+[c] '''+''' 1 an N10-formyl-tetrahydrofolate[c]
+
** 1 a [2-oxoglutarate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine[c] '''+''' 1 succinyl-CoA[c] '''<=>''' 1 coenzyme A[c] '''+''' 1 a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine[c]
  
 
== Genes associated with this reaction  ==
 
== Genes associated with this reaction  ==
 
Genes have been associated with this reaction based on different elements listed below.
 
Genes have been associated with this reaction based on different elements listed below.
−
* [[CHC_T00008670001_1]]
+
* Gene: [[CHC_T00010287001_1]]
−
** [[pantograph]]-[[galdieria.sulphuraria]]
+
** Source: [[orthology-galdieria.sulphuraria]]
−
* [[CHC_T00008680001_1]]
+
** Source: [[orthology-ectocarpus_siliculosus]]
−
** [[pantograph]]-[[galdieria.sulphuraria]]
+
* Gene: [[CHC_T00010023001_1]]
 +
** Source: [[orthology-galdieria.sulphuraria]]
 +
* Gene: [[CHC_T00008312001_1]]
 +
** Source: [[orthology-galdieria.sulphuraria]]
 +
* Gene: [[CHC_T00008312001]]
 +
** Source: [[annotation-original_genome]]
 +
*** Assignment: AUTOMATED-NAME-MATCH
 +
* Gene: [[CHC_T00008441001_1]]
 +
** Source: [[orthology-galdieria.sulphuraria]]
 +
** Source: [[orthology-ectocarpus_siliculosus]]
 +
* Gene: [[CHC_T00008441001]]
 +
** Source: [[annotation-original_genome]]
 +
*** Assignment: AUTOMATED-NAME-MATCH
 
== Pathways  ==
 
== Pathways  ==
−
* [[PWY-1722]], formate assimilation into 5,10-methylenetetrahydrofolate: [http://metacyc.org/META/NEW-IMAGE?object=PWY-1722 PWY-1722]
+
* [[PWY66-398]], TCA cycle III (animals): [http://metacyc.org/META/NEW-IMAGE?object=PWY66-398 PWY66-398]
 +
** '''11''' reactions found over '''11''' reactions in the full pathway
 +
* [[PWY-5084]], 2-oxoglutarate decarboxylation to succinyl-CoA: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5084 PWY-5084]
 
** '''3''' reactions found over '''3''' reactions in the full pathway
 
** '''3''' reactions found over '''3''' reactions in the full pathway
−
* [[PWY-3841]], folate transformations II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-3841 PWY-3841]
 
−
** '''7''' reactions found over '''11''' reactions in the full pathway
 
−
* [[1CMET2-PWY]], N10-formyl-tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=1CMET2-PWY 1CMET2-PWY]
 
−
** '''6''' reactions found over '''9''' reactions in the full pathway
 
−
* [[PWY-5030]], L-histidine degradation III: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5030 PWY-5030]
 
−
** '''1''' reactions found over '''6''' reactions in the full pathway
 
−
* [[P164-PWY]], purine nucleobases degradation I (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=P164-PWY P164-PWY]
 
−
** '''3''' reactions found over '''17''' reactions in the full pathway
 
−
* [[CODH-PWY]], reductive acetyl coenzyme A pathway I (homoacetogenic bacteria): [http://metacyc.org/META/NEW-IMAGE?object=CODH-PWY CODH-PWY]
 
−
** '''4''' reactions found over '''9''' reactions in the full pathway
 
−
* [[PWY-5497]], purine nucleobases degradation II (anaerobic): [http://metacyc.org/META/NEW-IMAGE?object=PWY-5497 PWY-5497]
 
−
** '''7''' reactions found over '''24''' reactions in the full pathway
 
−
* [[PWY-2201]], folate transformations I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-2201 PWY-2201]
 
−
** '''5''' reactions found over '''12''' reactions in the full pathway
 
−
* [[PWY-6613]], tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6613 PWY-6613]
 
−
** '''2''' reactions found over '''2''' reactions in the full pathway
 
 
== Reconstruction information  ==
 
== Reconstruction information  ==
−
* [[orthology]]:
+
* Category: [[orthology]]
−
** [[pantograph]]:
+
** Source: [[orthology-ectocarpus_siliculosus]]
−
*** [[galdieria.sulphuraria]]
+
*** Tool: [[pantograph]]
−
* [[annotation]]:
+
** Source: [[orthology-galdieria.sulphuraria]]
−
** [[pathwaytools]]:
+
*** Tool: [[pantograph]]
−
*** [[original_genome]]
+
* Category: [[annotation]]
 +
** Source: [[annotation-original_genome]]
 +
*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
−
* RHEA:
 
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=23700 23700]
 
 
* LIGAND-RXN:
 
* LIGAND-RXN:
−
** [http://www.genome.jp/dbget-bin/www_bget?R01655 R01655]
+
** [http://www.genome.jp/dbget-bin/www_bget?R01940 R01940]
−
* UNIPROT:
+
** [http://www.genome.jp/dbget-bin/www_bget?R02570 R02570]
−
** [http://www.uniprot.org/uniprot/P09440 P09440]
+
−
** [http://www.uniprot.org/uniprot/P07245 P07245]
+
−
** [http://www.uniprot.org/uniprot/P11586 P11586]
+
−
** [http://www.uniprot.org/uniprot/P18155 P18155]
+
−
** [http://www.uniprot.org/uniprot/P44313 P44313]
+
−
** [http://www.uniprot.org/uniprot/P47259 P47259]
+
−
** [http://www.uniprot.org/uniprot/P13995 P13995]
+
−
** [http://www.uniprot.org/uniprot/P54382 P54382]
+
−
** [http://www.uniprot.org/uniprot/O67736 O67736]
+
−
** [http://www.uniprot.org/uniprot/Q9JWI9 Q9JWI9]
+
−
** [http://www.uniprot.org/uniprot/Q9PP68 Q9PP68]
+
−
** [http://www.uniprot.org/uniprot/P24186 P24186]
+
−
** [http://www.uniprot.org/uniprot/Q04448 Q04448]
+
−
** [http://www.uniprot.org/uniprot/Q60006 Q60006]
+
−
** [http://www.uniprot.org/uniprot/Q27772 Q27772]
+
−
** [http://www.uniprot.org/uniprot/P51696 P51696]
+
−
** [http://www.uniprot.org/uniprot/O68031 O68031]
+
−
** [http://www.uniprot.org/uniprot/Q9ZTV0 Q9ZTV0]
+
−
** [http://www.uniprot.org/uniprot/Q9X7F6 Q9X7F6]
+
 
{{#set: direction=REVERSIBLE}}
 
{{#set: direction=REVERSIBLE}}
−
{{#set: ec number=EC-3.5.4.9}}
+
{{#set: common name=2-oxoglutarate dehydrogenase, E1 component}}
−
{{#set: gene associated=CHC_T00008670001_1|CHC_T00008680001_1}}
+
{{#set: common name=dihydrolipoamide dehydrogenase}}
−
{{#set: in pathway=PWY-1722|PWY-3841|1CMET2-PWY|PWY-5030|P164-PWY|CODH-PWY|PWY-5497|PWY-2201|PWY-6613}}
+
{{#set: ec number=EC-2.3.1.61}}
−
{{#set: reconstruction category=orthology}}
+
{{#set: gene associated=CHC_T00010287001_1|CHC_T00010023001_1|CHC_T00008312001_1|CHC_T00008312001|CHC_T00008441001_1|CHC_T00008441001}}
−
{{#set: reconstruction tool=pantograph}}
+
{{#set: in pathway=PWY66-398|PWY-5084}}
−
{{#set: reconstruction source=galdieria.sulphuraria}}
+
{{#set: reconstruction category=orthology|annotation}}
−
{{#set: reconstruction category=annotation}}
+
{{#set: reconstruction source=annotation-original_genome|orthology-ectocarpus_siliculosus|orthology-galdieria.sulphuraria}}
−
{{#set: reconstruction tool=pathwaytools}}
+
{{#set: reconstruction tool=pantograph|pathwaytools}}
−
{{#set: reconstruction source=original_genome}}
+

Revision as of 16:50, 23 May 2018

Reaction RXN0-1147

  • direction:
    • REVERSIBLE
  • common name:
    • 2-oxoglutarate dehydrogenase, E1 component
    • dihydrolipoamide dehydrogenase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY66-398, TCA cycle III (animals): PWY66-398
    • 11 reactions found over 11 reactions in the full pathway
  • PWY-5084, 2-oxoglutarate decarboxylation to succinyl-CoA: PWY-5084
    • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

External links





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