Difference between revisions of "URATE"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=UROPORIIIMETHYLTRANSA-RXN UROPORIIIMETHYLTRANSA-RXN] == * direction: ** LEFT-TO-RIGHT * Synonym(s):...")
(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=URATE URATE] == * smiles: ** C12(NC(=O)NC=1C(=O)NC(=O)N2) * inchi key: ** InChIKey=LEHOTFFKMJEO...")
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[[Category:Reaction]]
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[[Category:Metabolite]]
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=UROPORIIIMETHYLTRANSA-RXN UROPORIIIMETHYLTRANSA-RXN] ==
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=URATE URATE] ==
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* direction:
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* smiles:
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** LEFT-TO-RIGHT
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** C12(NC(=O)NC=1C(=O)NC(=O)N2)
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* inchi key:
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** InChIKey=LEHOTFFKMJEONL-UHFFFAOYSA-N
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* common name:
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** urate
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* molecular weight:
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** 168.112   
 
* Synonym(s):
 
* Synonym(s):
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** uroporphyrinogen methyltransferase
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** 2,6,8-trioxypurine
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** uroporphyrinogen-III methyltransferase
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** purine-2,6,8-(1H,3H,9H)-trione
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** adenosylmethionine-uroporphyrinogen III methyltransferase
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** 7,9-dihydro-1H-purine-2,6,8(3H)-trione
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** S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase
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** SirA
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** CysG
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** uroporphyrin-III C-methyltransferase (incorrect)
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** S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase (incorrect)
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== Reaction Formula ==
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== Reaction(s) known to consume the compound ==
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* With identifiers:
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* [[URATE-OXIDASE-RXN]]
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** 1 [[S-ADENOSYLMETHIONINE]][c] '''+''' 1 [[UROPORPHYRINOGEN-III]][c] '''=>''' 1 [[ADENOSYL-HOMO-CYS]][c] '''+''' 1 [[CPD-9038]][c] '''+''' 1 [[PROTON]][c]
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== Reaction(s) known to produce the compound ==
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* With common name(s):
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* [[XANTHINE-OXIDASE-RXN]]
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** 1 S-adenosyl-L-methionine[c] '''+''' 1 uroporphyrinogen-III[c] '''=>''' 1 S-adenosyl-L-homocysteine[c] '''+''' 1 precorrin-1[c] '''+''' 1 H+[c]
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== Reaction(s) of unknown directionality ==
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* [[RXN0-901]]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* [[CHC_T00000927001_1]]
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** [[pantograph]]-[[galdieria.sulphuraria]]
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== Pathways  ==
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* [[PWY-7376]], cob(II)yrinate a,c-diamide biosynthesis II (late cobalt incorporation): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7376 PWY-7376]
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** '''2''' reactions found over '''13''' reactions in the full pathway
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* [[PWY-7377]], cob(II)yrinate a,c-diamide biosynthesis I (early cobalt insertion): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7377 PWY-7377]
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** '''3''' reactions found over '''15''' reactions in the full pathway
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* [[PWY-5194]], siroheme biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5194 PWY-5194]
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** '''2''' reactions found over '''4''' reactions in the full pathway
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* [[PWY-5196]], factor 430 biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-5196 PWY-5196]
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** '''2''' reactions found over '''7''' reactions in the full pathway
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== Reconstruction information  ==
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* [[orthology]]:
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** [[pantograph]]:
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*** [[galdieria.sulphuraria]]
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== External links  ==
 
== External links  ==
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* RHEA:
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* CAS : 69-93-2
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=19089 19089]
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* Wikipedia : Uric_acid
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* LIGAND-RXN:
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* METABOLIGHTS : MTBLC17775
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** [http://www.genome.jp/dbget-bin/www_bget?R07237 R07237]
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* DRUGBANK : DB01696
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{{#set: direction=LEFT-TO-RIGHT}}
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* PUBCHEM:
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{{#set: common name=uroporphyrinogen methyltransferase|uroporphyrinogen-III methyltransferase|adenosylmethionine-uroporphyrinogen III methyltransferase|S-adenosyl-L-methionine-dependent uroporphyrinogen III methylase|SirA|CysG|uroporphyrin-III C-methyltransferase (incorrect)|S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase (incorrect)}}
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** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=44229235 44229235]
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{{#set: gene associated=CHC_T00000927001_1}}
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* HMDB : HMDB00289
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{{#set: in pathway=PWY-7376|PWY-7377|PWY-5194|PWY-5196}}
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* LIGAND-CPD:
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{{#set: reconstruction category=orthology}}
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** [http://www.genome.jp/dbget-bin/www_bget?C00366 C00366]
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{{#set: reconstruction tool=pantograph}}
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* CHEBI:
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{{#set: reconstruction source=galdieria.sulphuraria}}
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** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=17775 17775]
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* BIGG : urate
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{{#set: smiles=C12(NC(=O)NC=1C(=O)NC(=O)N2)}}
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{{#set: inchi key=InChIKey=LEHOTFFKMJEONL-UHFFFAOYSA-N}}
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{{#set: common name=urate}}
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{{#set: molecular weight=168.112    }}
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{{#set: common name=2,6,8-trioxypurine|purine-2,6,8-(1H,3H,9H)-trione|7,9-dihydro-1H-purine-2,6,8(3H)-trione}}
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{{#set: consumed by=URATE-OXIDASE-RXN}}
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{{#set: produced by=XANTHINE-OXIDASE-RXN}}
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{{#set: reversible reaction associated=RXN0-901}}

Revision as of 15:11, 23 May 2018

Metabolite URATE

  • smiles:
    • C12(NC(=O)NC=1C(=O)NC(=O)N2)
  • inchi key:
    • InChIKey=LEHOTFFKMJEONL-UHFFFAOYSA-N
  • common name:
    • urate
  • molecular weight:
    • 168.112
  • Synonym(s):
    • 2,6,8-trioxypurine
    • purine-2,6,8-(1H,3H,9H)-trione
    • 7,9-dihydro-1H-purine-2,6,8(3H)-trione

Reaction(s) known to consume the compound

Reaction(s) known to produce the compound

Reaction(s) of unknown directionality

External links

  • CAS : 69-93-2
  • Wikipedia : Uric_acid
  • METABOLIGHTS : MTBLC17775
  • DRUGBANK : DB01696
  • PUBCHEM:
  • HMDB : HMDB00289
  • LIGAND-CPD:
  • CHEBI:
  • BIGG : urate





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