Difference between revisions of "PWY-3341"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=URATE URATE] == * smiles: ** C12(NC(=O)NC=1C(=O)NC(=O)N2) * inchi key: ** InChIKey=LEHOTFFKMJEO...")
 
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=DIHYDROFOLATESYNTH-RXN DIHYDROFOLATESYNTH-RXN] == * direction: ** LEFT-TO-RIGHT * ec number: ** [ht...")
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[[Category:Metabolite]]
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[[Category:Reaction]]
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=URATE URATE] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=DIHYDROFOLATESYNTH-RXN DIHYDROFOLATESYNTH-RXN] ==
* smiles:
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* direction:
** C12(NC(=O)NC=1C(=O)NC(=O)N2)
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** LEFT-TO-RIGHT
* inchi key:
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* ec number:
** InChIKey=LEHOTFFKMJEONL-UHFFFAOYSA-N
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** [http://enzyme.expasy.org/EC/6.3.2.12 EC-6.3.2.12]
* common name:
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** urate
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* molecular weight:
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** 168.112   
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* Synonym(s):
 
* Synonym(s):
** 2,6,8-trioxypurine
 
** purine-2,6,8-(1H,3H,9H)-trione
 
** 7,9-dihydro-1H-purine-2,6,8(3H)-trione
 
  
== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
* [[URATE-OXIDASE-RXN]]
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* With identifiers:
== Reaction(s) known to produce the compound ==
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** 1 [[7-8-DIHYDROPTEROATE]][c] '''+''' 1 [[ATP]][c] '''+''' 1 [[GLT]][c] '''=>''' 1 [[ADP]][c] '''+''' 1 [[DIHYDROFOLATE]][c] '''+''' 1 [[Pi]][c] '''+''' 1 [[PROTON]][c]
* [[XANTHINE-OXIDASE-RXN]]
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* With common name(s):
== Reaction(s) of unknown directionality ==
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** 1 7,8-dihydropteroate[c] '''+''' 1 ATP[c] '''+''' 1 L-glutamate[c] '''=>''' 1 ADP[c] '''+''' 1 7,8-dihydrofolate monoglutamate[c] '''+''' 1 phosphate[c] '''+''' 1 H+[c]
* [[RXN0-901]]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* [[CHC_T00000400001_1]]
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** [[pantograph]]-[[galdieria.sulphuraria]]
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== Pathways  ==
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* [[PWY-6614]], tetrahydrofolate biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6614 PWY-6614]
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** '''3''' reactions found over '''3''' reactions in the full pathway
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== Reconstruction information  ==
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* [[orthology]]:
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** [[pantograph]]:
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*** [[galdieria.sulphuraria]]
 
== External links  ==
 
== External links  ==
* CAS : 69-93-2
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* RHEA:
* Wikipedia : Uric_acid
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=23584 23584]
* METABOLIGHTS : MTBLC17775
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* LIGAND-RXN:
* DRUGBANK : DB01696
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** [http://www.genome.jp/dbget-bin/www_bget?R02237 R02237]
* PUBCHEM:
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* UNIPROT:
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=44229235 44229235]
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** [http://www.uniprot.org/uniprot/Q9JVC6 Q9JVC6]
* HMDB : HMDB00289
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** [http://www.uniprot.org/uniprot/P43775 P43775]
* LIGAND-CPD:
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** [http://www.uniprot.org/uniprot/Q9PNK6 Q9PNK6]
** [http://www.genome.jp/dbget-bin/www_bget?C00366 C00366]
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** [http://www.uniprot.org/uniprot/Q50990 Q50990]
* CHEBI:
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** [http://www.uniprot.org/uniprot/P08192 P08192]
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=17775 17775]
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{{#set: direction=LEFT-TO-RIGHT}}
* BIGG : urate
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{{#set: ec number=EC-6.3.2.12}}
{{#set: smiles=C12(NC(=O)NC=1C(=O)NC(=O)N2)}}
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{{#set: gene associated=CHC_T00000400001_1}}
{{#set: inchi key=InChIKey=LEHOTFFKMJEONL-UHFFFAOYSA-N}}
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{{#set: in pathway=PWY-6614}}
{{#set: common name=urate}}
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{{#set: reconstruction category=orthology}}
{{#set: molecular weight=168.112    }}
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{{#set: reconstruction tool=pantograph}}
{{#set: common name=2,6,8-trioxypurine|purine-2,6,8-(1H,3H,9H)-trione|7,9-dihydro-1H-purine-2,6,8(3H)-trione}}
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{{#set: reconstruction source=galdieria.sulphuraria}}
{{#set: consumed by=URATE-OXIDASE-RXN}}
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{{#set: produced by=XANTHINE-OXIDASE-RXN}}
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{{#set: consumed or produced by=RXN0-901}}
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Revision as of 12:00, 18 January 2018

Reaction DIHYDROFOLATESYNTH-RXN

  • direction:
    • LEFT-TO-RIGHT
  • ec number:
  • Synonym(s):

Reaction Formula

  • With identifiers:
  • With common name(s):
    • 1 7,8-dihydropteroate[c] + 1 ATP[c] + 1 L-glutamate[c] => 1 ADP[c] + 1 7,8-dihydrofolate monoglutamate[c] + 1 phosphate[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY-6614, tetrahydrofolate biosynthesis: PWY-6614
    • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

External links