RXN66-315

Reaction RXN66-315

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 4α-methyl-zymosterol 4-hydroxylase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 4-METHYL-824-CHOLESTADIENOL[c] + 1 PROTON[c] + 1 NADH-P-OR-NOP[c] + 1 OXYGEN-MOLECULE[c] => 1 CPD-4579[c] + 1 NAD-P-OR-NOP[c] + 1 WATER[c]
• With common name(s):
  • 1 4α-methyl-zymosterol[c] + 1 H+[c] + 1 NAD(P)H[c] + 1 oxygen[c] => 1 4α-hydroxymethyl-5α-cholesta-8,24-dien-3β-ol[c] + 1 NAD(P)+[c] + 1 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: CHC_T00010320001_1
  • Source: orthology-galdieria.sulphuraria

Pathways

• PWY66-341, cholesterol biosynthesis I: PWY66-341
  • 15 reactions found over 22 reactions in the full pathway
• PWY-6074, zymosterol biosynthesis: PWY-6074
  • 10 reactions found over 12 reactions in the full pathway
• PWY66-4, cholesterol biosynthesis III (via desmosterol): PWY66-4
  • 16 reactions found over 22 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-galdieria.sulphuraria
    • Tool: pantograph