NMNH

Reaction RXN-8991

• direction:
  • REVERSIBLE
• common name:
  • 3-isopropylmalate dehydratase
  • 3-isopropylmalate dehydratase small subunit
• Synonym(s):
  • (2R,3S)-3-isopropylmalate hydro-lyase
  • β-isopropylmalate dehydratase
  • α-isopropylmalate isomerase
  • 3-isopropylmalate hydro-lyase

Reaction Formula

• With identifiers:
  • 1 2-D-THREO-HYDROXY-3-CARBOXY-ISOCAPROATE[c] <=> 1 CPD-9451[c] + 1 WATER[c]
• With common name(s):
  • 1 (2R,3S)-3-isopropylmalate[c] <=> 1 2-isopropylmaleate[c] + 1 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• CHC_T00009087001
  • ORIGINAL_GENOME
    • AUTOMATED-NAME-MATCH
• CHC_T00009087001_1
  • pantograph-galdieria.sulphuraria
  • pantograph-a.taliana
• CHC_T00009184001
  • ORIGINAL_GENOME
    • AUTOMATED-NAME-MATCH
• CHC_T00009184001_1
  • pantograph-galdieria.sulphuraria
  • pantograph-a.taliana

Pathways

• LEUSYN-PWY, L-leucine biosynthesis: LEUSYN-PWY
  • 6 reactions found over 6 reactions in the full pathway
• PWY-6871, 3-methylbutanol biosynthesis (engineered): PWY-6871
  • 7 reactions found over 7 reactions in the full pathway

Reconstruction information

• orthology:
  • pantograph:
    • galdieria.sulphuraria
    • a.taliana
• annotation:
  • pathwaytools:
    • original_genome

External links

• RHEA:
  • 10676
• LIGAND-RXN:
  • R04001