ISOCITRATE-DEHYDROGENASE-NAD+-RXN

Reaction ISOCITRATE-DEHYDROGENASE-NAD+-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Isocitrate dehydrogenase, NAD-dependent
  • isocitrate dehydrogenase (NAD+) subunit 2, mitochondrial precursor
• ec number:
  • EC-1.1.1.286
  • EC-1.1.1.41
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 THREO-DS-ISO-CITRATE[c] => 1 2-KETOGLUTARATE[c] + 1 NADH[c] + 1 CARBON-DIOXIDE[c]
• With common name(s):
  • 1 NAD+[c] + 1 D-threo-isocitrate[c] => 1 2-oxoglutarate[c] + 1 NADH[c] + 1 CO2[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: CHC_T00008852001_1
  • Source: orthology-galdieria.sulphuraria
• Gene: CHC_T00008852001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: CHC_T00009162001_1
  • Source: orthology-galdieria.sulphuraria
• Gene: CHC_T00009293001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: CHC_T00009293001_1
  • Source: orthology-galdieria.sulphuraria
• Gene: CHC_T00009162001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH

Pathways

• PWY-6549, L-glutamine biosynthesis III: PWY-6549
  • 9 reactions found over 9 reactions in the full pathway
• PWY66-398, TCA cycle III (animals): PWY66-398
  • 11 reactions found over 11 reactions in the full pathway
• PWY-5690, TCA cycle II (plants and fungi): PWY-5690
  • 9 reactions found over 9 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-galdieria.sulphuraria
    • Tool: pantograph
• Category: annotation
  • Source: annotation-original_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 23632
• LIGAND-RXN:
  • R00709
• UNIPROT:
  • P56472
  • P41566
  • P28834
  • P41565
  • P41564
  • P50213
  • Q7M3F1
  • P41563
  • Q28479
  • Q28480
  • O65852
  • O65501
  • O82004
  • O43837
  • O13696
  • Q9USP8