HOMOGENTISATE-12-DIOXYGENASE-RXN

Reaction HOMOGENTISATE-12-DIOXYGENASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • homogentisate 1,2-dioxygenase
• ec number:
  • EC-1.13.11.5
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 HOMOGENTISATE[c] + 1 OXYGEN-MOLECULE[c] => 1 4-MALEYL-ACETOACETATE[c] + 1 PROTON[c]
• With common name(s):
  • 1 homogentisate[c] + 1 oxygen[c] => 1 4-maleyl-acetoacetate[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: CHC_T00008952001_1
  • Source: orthology-galdieria.sulphuraria
  • Source: orthology-ectocarpus_siliculosus
• Gene: CHC_T00008952001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH

Pathways

• TYRFUMCAT-PWY, L-tyrosine degradation I: TYRFUMCAT-PWY
  • 5 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-galdieria.sulphuraria
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-original_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 15449
• UNIPROT:
  • Q9Y041
• LIGAND-RXN:
  • R02519