AIRS-RXN

Reaction AIRS-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • phosphoribosylformylglycinamidine cyclo-ligase (phosphoribosyl-aminoimidazole synthetase) (AIR synthase)
• ec number:
  • EC-6.3.3.1
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 5-PHOSPHORIBOSYL-N-FORMYLGLYCINEAMIDINE[c] + 1 ATP[c] => 1 5-PHOSPHORIBOSYL-5-AMINOIMIDAZOLE[c] + 1 Pi[c] + 1 ADP[c] + 1 PROTON[c]
• With common name(s):
  • 1 2-(formamido)-N1-(5-phospho-β-D-ribosyl)acetamidine[c] + 1 ATP[c] => 1 5-amino-1-(5-phospho-β-D-ribosyl)imidazole[c] + 1 phosphate[c] + 1 ADP[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: CHC_T00008410001_1
  • Source: orthology-galdieria.sulphuraria
• Gene: CHC_T00008410001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH

Pathways

• PWY-6122, 5-aminoimidazole ribonucleotide biosynthesis II: PWY-6122
  • 5 reactions found over 5 reactions in the full pathway
• PWY-6277, superpathway of 5-aminoimidazole ribonucleotide biosynthesis: PWY-6277
  • 7 reactions found over 9 reactions in the full pathway
• PWY-6121, 5-aminoimidazole ribonucleotide biosynthesis I: PWY-6121
  • 5 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-galdieria.sulphuraria
    • Tool: pantograph
• Category: annotation
  • Source: annotation-original_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 23032
• UNIPROT:
  • P07244
  • P12043
  • P21872
  • P08178
  • P00967
  • P16340
  • P22102
  • Q57656
  • O66968
  • Q9JUA2
  • P43848
  • Q9PME0
  • Q64737
  • P20772
  • Q55422
  • P52424
• LIGAND-RXN:
  • R04208