RXN0-1147

Reaction RXN0-1147

• direction:
  • REVERSIBLE
• common name:
  • 2-oxoglutarate dehydrogenase, E1 component
  • dihydrolipoamide dehydrogenase
• ec number:
  • EC-2.3.1.61
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 Oxo-glutarate-dehydrogenase-DH-lipoyl[c] + 1 SUC-COA[c] <=> 1 CO-A[c] + 1 Oxo-glutarate-dehydro-suc-DH-lipoyl[c]
• With common name(s):
  • 1 a [2-oxoglutarate dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine[c] + 1 succinyl-CoA[c] <=> 1 coenzyme A[c] + 1 a [2-oxoglutarate dehydrogenase E2 protein] N6-S-succinyldihydrolipoyl-L-lysine[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: CHC_T00010287001_1
  • Source: orthology-galdieria.sulphuraria
  • Source: orthology-ectocarpus_siliculosus
• Gene: CHC_T00010023001_1
  • Source: orthology-galdieria.sulphuraria
• Gene: CHC_T00008312001_1
  • Source: orthology-galdieria.sulphuraria
• Gene: CHC_T00008312001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: CHC_T00008441001_1
  • Source: orthology-galdieria.sulphuraria
  • Source: orthology-ectocarpus_siliculosus
• Gene: CHC_T00008441001
  • Source: annotation-original_genome
    • Assignment: AUTOMATED-NAME-MATCH

Pathways

• PWY66-398, TCA cycle III (animals): PWY66-398
  • 11 reactions found over 11 reactions in the full pathway
• PWY-5084, 2-oxoglutarate decarboxylation to succinyl-CoA: PWY-5084
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-galdieria.sulphuraria
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-original_genome
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R01940
  • R02570