PHOSPHORIBULOSYL-FORMIMINO-AICAR-P

Reaction RXN-5471

direction:
- LEFT-TO-RIGHT
common name:
- dolichyl-P-Glc:Glc1Man2GlcNAc2-PPdolichol α-1,3-glucosyltransferase
ec number:
- EC-2.4.1.265
Synonym(s):

With identifiers:
- 1 CPD-5169[c] + 1 CPD-166[c] => 1 DOLICHOLP[c] + 1 PROTON[c] + 1 CPD-5170[c]
With common name(s):
- 1 α-D-Glc-(1→3)-α-D-Man-(1→2)-α-D-Man-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→2)-α-D-Man-(1→6)]-α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-α-D-GlcNAc-diphosphodolichol[c] + 1 a dolichyl β-D-glucosyl phosphate[c] => 1 a dolichyl phosphate[c] + 1 H+[c] + 1 α-D-Glc-(1→3)-α-D-Glc-(1→3)-α-D-Man-(1→2)-α-D-Man-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→2)-α-D-Man-(1→3)-[α-D-Man-(1→2)-α-D-Man-(1→6)]-α-D-Man-(1→6)]-β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-α-D-GlcNAc-diphosphodolichol[c]

Genes have been associated with this reaction based on different elements listed below.

MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS, protein N-glycosylation (eukaryotic, high mannose): MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS
- 12 reactions found over 19 reactions in the full pathway