PORPHOBILSYNTH-RXN

Reaction PORPHOBILSYNTH-RXN

• ec number:
  • EC-4.2.1.24
• direction:
  • LEFT-TO-RIGHT
• common name:
  • porphobilinogen synthase
• Synonym(s):

Reaction Formula

• With identifiers:
  • 2 5-AMINO-LEVULINATE[c] => 1 PROTON[c] + 2 WATER[c] + 1 PORPHOBILINOGEN[c]
• With common name(s):
  • 2 5-aminolevulinate[c] => 1 H+[c] + 2 H2O[c] + 1 porphobilinogen[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: g16959.t1
  • Source: annotation-cladosiphon_okamuranus
    • Assignment: GO-TERM
  • Source: orthology-ectocarpus_siliculosus
  • Source: orthology-nannochloropsis_salina
  • Source: orthology-arabidopsis_thaliana
  • Source: orthology-saccharina_japonica

Pathways

• PWY-5188, tetrapyrrole biosynthesis I (from glutamate): PWY-5188
  • 6 reactions found over 6 reactions in the full pathway
• PWY-5189, tetrapyrrole biosynthesis II (from glycine): PWY-5189
  • 4 reactions found over 4 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-saccharina_japonica
    • Tool: pantograph
  • Source: orthology-ectocarpus_siliculosus
    • Tool: pantograph
  • Source: orthology-nannochloropsis_salina
    • Tool: pantograph
  • Source: orthology-arabidopsis_thaliana
    • Tool: pantograph
• Category: annotation
  • Source: annotation-cladosiphon_okamuranus
    • Tool: pathwaytools

External links

• UNIPROT:
  • P06214
  • P13716
  • Q7M315
  • P30124
  • Q9JV37
  • P30950
  • Q60178
  • Q9PNU5
  • Q59295
  • Q02250
  • P10518
  • Q43148
  • Q42682
  • Q43058
  • Q59643
  • Q9S8B1
  • P05373
  • P0ACB2
  • Q42836
  • P43210
  • Q9ZNC9
• RHEA:
  • 24064
• LIGAND-RXN:
  • R00036