2-ISOPROPYLMALATESYN-RXN
From metabolic_network
Contents
Reaction 2-ISOPROPYLMALATESYN-RXN
- direction:
- LEFT-TO-RIGHT
- common name:
- 2-Isopropylmalate synthase
- ec number:
- Synonym(s):
Reaction Formula
- With identifiers:
- 1 2-KETO-ISOVALERATE[c] + 1 WATER[c] + 1 ACETYL-COA[c] => 1 3-CARBOXY-3-HYDROXY-ISOCAPROATE[c] + 1 CO-A[c] + 1 PROTON[c]
- With common name(s):
- 1 3-methyl-2-oxobutanoate[c] + 1 H2O[c] + 1 acetyl-CoA[c] => 1 (2S)-2-isopropylmalate[c] + 1 coenzyme A[c] + 1 H+[c]
Genes associated with this reaction
Genes have been associated with this reaction based on different elements listed below.
- Gene: Ec-28_002630
- Source: annotation-esiliculosus_genome
- Assignment: EC-NUMBER
- Source: annotation-esiliculosus_genome
- Gene: Ec-18_000460
- Source: annotation-esiliculosus_genome
- Assignment: EC-NUMBER
- Source: orthology-aragem
- Source: annotation-esiliculosus_genome
Pathways
- LEUSYN-PWY, L-leucine biosynthesis: LEUSYN-PWY
- 6 reactions found over 6 reactions in the full pathway
- PWY-6871, 3-methylbutanol biosynthesis (engineered): PWY-6871
- 6 reactions found over 7 reactions in the full pathway
Reconstruction information
- Category: orthology
- Source: orthology-aragem
- Tool: pantograph
- Source: orthology-aragem
- Category: manual
- Source: manual-erythro
- Source: manual-sphingo361
- Source: manual-sphingo391
- Source: manual-roseov420
- Source: manual-rhizobi
- Source: manual-hoflea
- Source: manual-imperaili
- Source: manual-roseov134
- Source: manual-marino
- Source: manual-bosea
- Category: annotation
- Source: annotation-esiliculosus_genome
- Tool: pathwaytools
- Source: annotation-esiliculosus_genome
External links
- RHEA:
- LIGAND-RXN:
- UNIPROT: