DIHYDROFOLATESYNTH-RXN

Reaction DIHYDROFOLATESYNTH-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • Folylpolyglutamate synthase, mitochondrial
  • Folylpolyglutamate synthetase
• ec number:
  • EC-6.3.2.12
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 GLT[c] + 1 7-8-DIHYDROPTEROATE[c] + 1 ATP[c] => 1 DIHYDROFOLATE[c] + 1 ADP[c] + 1 PROTON[c] + 1 Pi[c]
• With common name(s):
  • 1 L-glutamate[c] + 1 7,8-dihydropteroate[c] + 1 ATP[c] => 1 7,8-dihydrofolate monoglutamate[c] + 1 ADP[c] + 1 H+[c] + 1 phosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-07_002300
  • Source: annotation-esiliculosus_genome
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: Ec-01_004980
  • Source: annotation-esiliculosus_genome
    • Assignment: AUTOMATED-NAME-MATCH

Pathways

• PWY-6614, tetrahydrofolate biosynthesis: PWY-6614
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: manual
  • Source: manual-erythro
  • Source: manual-sphingo361
  • Source: manual-sphingo391
  • Source: manual-hoflea
  • Source: manual-rhizobi
  • Source: manual-roseov420
  • Source: manual-imperaili
  • Source: manual-roseov134
  • Source: manual-marino
  • Source: manual-bosea
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• RHEA:
  • 23584
• LIGAND-RXN:
  • R02237
• UNIPROT:
  • Q9JVC6
  • P43775
  • Q9PNK6
  • Q50990
  • P08192