GTP-CYCLOHYDRO-II-RXN

Reaction GTP-CYCLOHYDRO-II-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • GTP cyclohydrolase II
• ec number:
  • EC-3.5.4.25
• Synonym(s):

Reaction Formula

• With identifiers:
  • 3 WATER[c] + 1 GTP[c] => 1 FORMATE[c] + 2 PROTON[c] + 1 PPI[c] + 1 DIAMINO-OH-PHOSPHORIBOSYLAMINO-PYR[c]
• With common name(s):
  • 3 H2O[c] + 1 GTP[c] => 1 formate[c] + 2 H+[c] + 1 diphosphate[c] + 1 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Ec-02_005710
  • Source: annotation-esiliculosus_genome
    • Assignment: GO-TERM
  • Source: orthology-aragem
• Gene: Ec-27_004040
  • Source: orthology-aragem

Pathways

• PWY-7539, 6-hydroxymethyl-dihydropterin diphosphate biosynthesis III (Chlamydia): PWY-7539
  • 4 reactions found over 5 reactions in the full pathway
• PWY-6168, flavin biosynthesis III (fungi): PWY-6168
  • 7 reactions found over 9 reactions in the full pathway
• RIBOSYN2-PWY, flavin biosynthesis I (bacteria and plants): RIBOSYN2-PWY
  • 9 reactions found over 9 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-aragem
    • Tool: pantograph
• Category: manual
  • Source: manual-erythro
  • Source: manual-sphingo361
  • Source: manual-sphingo391
  • Source: manual-hoflea
  • Source: manual-rhizobi
  • Source: manual-roseov420
  • Source: manual-imperaili
  • Source: manual-roseov134
  • Source: manual-marino
  • Source: manual-bosea
• Category: annotation
  • Source: annotation-esiliculosus_genome
    • Tool: pathwaytools

External links

• LIGAND-RXN:
  • R00425
• UNIPROT:
  • P0A7I7
  • Q9PNU4
  • O08315
  • O66679
  • Q9PHU4
  • O25484
  • P0A5V0
  • P0A7I8
  • P43525
  • P17620
  • P38066
  • P50139
  • P74104
  • O24019
  • P51695
  • P50855