Difference between revisions of "NADPH"

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(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLYRIBONUCSYN-RXN GLYRIBONUCSYN-RXN] == * direction: ** LEFT-TO-RIGHT * common name: ** phosphoribo...")
(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=NADPH NADPH] == * smiles: ** C5(N(C1(OC(C(C1O)O)COP(OP(OCC4(C(C(C(N3(C2(=C(C(=NC=N2)N)N=C3)))O4...")
 
(One intermediate revision by the same user not shown)
Line 1: Line 1:
−
[[Category:Reaction]]
+
[[Category:Metabolite]]
−
== Reaction [http://metacyc.org/META/NEW-IMAGE?object=GLYRIBONUCSYN-RXN GLYRIBONUCSYN-RXN] ==
+
== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=NADPH NADPH] ==
−
* direction:
+
* smiles:
−
** LEFT-TO-RIGHT
+
** C5(N(C1(OC(C(C1O)O)COP(OP(OCC4(C(C(C(N3(C2(=C(C(=NC=N2)N)N=C3)))O4)OP([O-])([O-])=O)O))([O-])=O)(=O)[O-]))C=C(CC=5)C(=O)N)
 +
* inchi key:
 +
** InChIKey=ACFIXJIJDZMPPO-NNYOXOHSSA-J
 
* common name:
 
* common name:
−
** phosphoribosylamine-glycine ligase
+
** NADPH
−
* ec number:
+
* molecular weight:
−
** [http://enzyme.expasy.org/EC/6.3.4.13 EC-6.3.4.13]
+
** 741.394   
 
* Synonym(s):
 
* Synonym(s):
 +
** reduced nicotinamide adenine dinucleotide phosphate
 +
** NADPH2
 +
** dihydrotriphosphopyridine nucleotide
 +
** reduced dihydrotriphosphopyridine nucleotide
 +
** dihydronicotinamide adenine dinucleotide phosphate
 +
** dihydronicotinamide adenine dinucleotide phosphate reduced
 +
** reduced NADP
 +
** NADP-red
 +
** TPNH
 +
** dihydronicotinamide adenine dinucleotide-P
 +
** β-NADPH
  
−
== Reaction Formula ==
+
== Reaction(s) known to consume the compound ==
−
* With identifiers:
+
* [[RXN-7660]]
−
** 1 [[ATP]][c] '''+''' 1 [[GLY]][c] '''+''' 1 [[5-P-BETA-D-RIBOSYL-AMINE]][c] '''=>''' 1 [[PROTON]][c] '''+''' 1 [[Pi]][c] '''+''' 1 [[5-PHOSPHO-RIBOSYL-GLYCINEAMIDE]][c] '''+''' 1 [[ADP]][c]
+
* [[RXN1G-1053]]
−
* With common name(s):
+
* [[RXN-4144]]
−
** 1 ATP[c] '''+''' 1 glycine[c] '''+''' 1 5-phospho-β-D-ribosylamine[c] '''=>''' 1 H+[c] '''+''' 1 phosphate[c] '''+''' 1 N1-(5-phospho-β-D-ribosyl)glycinamide[c] '''+''' 1 ADP[c]
+
* [[RXN-7665]]
−
 
+
* [[RXN-16616]]
−
== Genes associated with this reaction  ==
+
* [[RXN66-323]]
−
Genes have been associated with this reaction based on different elements listed below.
+
* [[RXN-711]]
−
* [[Ec-12_005490]]
+
* [[RXN-16129]]
−
** ESILICULOSUS_GENOME
+
* [[RXN-715]]
−
***GO-TERM
+
* [[RXN1G-349]]
−
** [[pantograph]]-[[aragem]]
+
* [[RXN-7664]]
−
== Pathways  ==
+
* [[RXN-600]]
−
* [[PWY-6121]], 5-aminoimidazole ribonucleotide biosynthesis I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6121 PWY-6121]
+
* [[1.14.13.70-RXN]]
−
** '''3''' reactions found over '''5''' reactions in the full pathway
+
* [[RXN-7666]]
−
* [[PWY-6122]], 5-aminoimidazole ribonucleotide biosynthesis II: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6122 PWY-6122]
+
* [[THIOREDOXIN-REDUCT-NADPH-RXN]]
−
** '''3''' reactions found over '''5''' reactions in the full pathway
+
* [[RXN-13307]]
−
* [[PWY-6277]], superpathway of 5-aminoimidazole ribonucleotide biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-6277 PWY-6277]
+
* [[RXN-17678]]
−
** '''5''' reactions found over '''9''' reactions in the full pathway
+
* [[RXN-4225]]
−
== Reconstruction information  ==
+
* [[RXN-9546]]
−
* Category: [[orthology]]
+
* [[RXN66-12]]
−
** Source: [[orthology-aragem]]
+
* [[RXN-17109]]
−
*** Tool: [[pantograph]]
+
* [[RXN-7677]]
−
* Category: [[annotation]]
+
* [[RXN-7676]]
−
** Source: [[annotation-esiliculosus_genome]]
+
* [[UDPNACETYLMURAMATEDEHYDROG-RXN]]
−
*** Tool: [[pathwaytools]]
+
* [[1.2.1.13-RXN]]
 +
* [[RXN-7784]]
 +
* [[RXN0-2142]]
 +
* [[RXN-13398]]
 +
* [[RXN1G-358]]
 +
* [[RXN-16114]]
 +
* [[RXN-16112]]
 +
* [[RXN-3142]]
 +
* [[RXN-15046]]
 +
* [[RXN-10625]]
 +
* [[GLUTSEMIALDEHYDROG-RXN]]
 +
* [[RXN1G-260]]
 +
* [[RXN1G-508]]
 +
* [[RXN-17428]]
 +
* [[RXN-13707]]
 +
* [[RXN-9536]]
 +
* [[RXN-9532]]
 +
* [[RXN-14014]]
 +
* [[RXN-11881]]
 +
* [[RXN-17111]]
 +
* [[RXN-1106]]
 +
* [[RXN1G-364]]
 +
* [[RXN-1102]]
 +
* [[RXN-1101]]
 +
* [[RXN1G-287]]
 +
* [[RXN-5285]]
 +
* [[RXN-9633]]
 +
* [[RXN-9524]]
 +
* [[RXN-9528]]
 +
* [[RXN1A0-6303]]
 +
* [[RXN0-1281]]
 +
* [[RXN-16765]]
 +
* [[RXN-14790]]
 +
* [[NADPH-DEHYDROGENASE-FLAVIN-RXN]]
 +
* [[GLUTRNAREDUCT-RXN]]
 +
* [[RXN-14715]]
 +
* [[RXN-9540]]
 +
* [[RXN-9556]]
 +
* [[RXN-13724]]
 +
* [[RXN-9552]]
 +
* [[RXN-707]]
 +
* [[RXN-13431]]
 +
* [[KYNURENINE-3-MONOOXYGENASE-RXN]]
 +
* [[RXN-4210]]
 +
* [[RXN1G-881]]
 +
* [[RXN-1125]]
 +
* [[RXN-10060]]
 +
* [[GMP-REDUCT-RXN]]
 +
* [[RXN-1121]]
 +
* [[RXN1G-469]]
 +
* [[3-HYDROXYBUTYRYL-COA-DEHYDROGENASE-RXN]]
 +
* [[1.14.13.79-RXN]]
 +
* [[DIENOYLCOAREDUCT-RXN]]
 +
* [[DIHYDROFOLATEREDUCT-RXN]]
 +
* [[RXN-14973]]
 +
* [[RXN-14972]]
 +
* [[1.1.1.271-RXN]]
 +
* [[RXN66-27]]
 +
* [[GLUTAMATESYN-RXN]]
 +
* [[RXN-7659]]
 +
* [[RXN-7658]]
 +
* [[RIBOFLAVINSYNREDUC-RXN]]
 +
* [[RXN-12521]]
 +
* [[FLAVONADPREDUCT-RXN]]
 +
* [[RXN-10655]]
 +
* [[PYRNUTRANSHYDROGEN-RXN]]
 +
* [[RXN-10659]]
 +
* [[RXN1G-163]]
 +
* [[RXN-16097]]
 +
* [[RXN-16095]]
 +
* [[RXN-16622]]
 +
* [[1.14.13.8-RXN]]
 +
* [[2-DEHYDROPANTOATE-REDUCT-RXN]]
 +
* [[RXN-8853]]
 +
* [[RXN-14776]]
 +
* [[TRANSENOYLCOARED-RXN]]
 +
* [[RXN-13299]]
 +
* [[GLYOXYLATE-REDUCTASE-NADP+-RXN]]
 +
* [[RXN-16016]]
 +
* [[RXN3O-130]]
 +
* [[RXN66-13]]
 +
* [[RXN66-11]]
 +
* [[ACETOOHBUTREDUCTOISOM-RXN]]
 +
* [[RXN66-14]]
 +
* [[GLUTATHIONE-REDUCT-NADPH-RXN]]
 +
* [[RXN-15006]]
 +
* [[RXN-12747]]
 +
* [[RXN-7835]]
 +
* [[RXN-11476]]
 +
* [[RXN-13961]]
 +
* [[RXN1G-240]]
 +
* [[RXN-16630]]
 +
* [[RXN66-305]]
 +
* [[RXN66-304]]
 +
* [[RXN66-306]]
 +
* [[RXN-773]]
 +
* [[RXN66-303]]
 +
* [[DIHYDROFOLATEREDUCT-RXN-THF/NADP//DIHYDROFOLATE/NADPH/PROTON.37.]]
 +
* [[SHIKIMATE-5-DEHYDROGENASE-RXN]]
 +
* [[RXN-11480]]
 +
* [[NITRATE-REDUCTASE-NADPH-RXN]]
 +
* [[1.5.1.8-RXN]]
 +
* [[RXN66-482]]
 +
* [[3-OXOACYL-ACP-REDUCT-RXN]]
 +
* [[RXN1G-72]]
 +
* [[RXN66-81]]
 +
* [[RXN-9725]]
 +
* [[DIHYDROKAEMPFEROL-4-REDUCTASE-RXN]]
 +
* [[1.5.1.19-RXN]]
 +
* [[SULFITE-REDUCT-RXN]]
 +
* [[RXN-16131]]
 +
* [[RXN-16626]]
 +
* [[RXN1F-160]]
 +
* [[RXN1F-161]]
 +
* [[RXN-9518]]
 +
* [[RXN-4231]]
 +
* [[RXN-9514]]
 +
* [[RXN-9515]]
 +
== Reaction(s) known to produce the compound ==
 +
* [[TRANS-RXN0-277]]
 +
* [[RXN-924]]
 +
* [[RXN-9952]]
 +
* [[MALIC-NADP-RXN]]
 +
* [[ALDEHYDE-DEHYDROGENASE-NADP+-RXN]]
 +
* [[RXN0-3962]]
 +
* [[1.18.1.2-RXN]]
 +
* [[RXN-5682]]
 +
* [[BENZALDEHYDE-DEHYDROGENASE-NADP+-RXN]]
 +
* [[GLU6PDEHYDROG-RXN]]
 +
== Reaction(s) of unknown directionality ==
 +
* [[ISOCITDEH-RXN]]
 +
* [[RXN-7911]]
 +
* [[RXN-1124]]
 +
* [[RXN1G-157]]
 +
* [[1.3.99.5-RXN]]
 +
* [[RXN-13008]]
 +
* [[GLUTDEHYD-RXN]]
 +
* [[METHYLENETHFDEHYDROG-NADP-RXN]]
 +
* [[RXN-8349_PLANTCYC]]
 +
* [[1.1.1.34-RXN]]
 +
* [[FATTY-ACID-SYNTHASE-RXN]]
 +
* [[DXPREDISOM-RXN]]
 +
* [[PREPHENATE-DEHYDROGENASE-NADP+-RXN]]
 +
* [[RXN-15115]]
 +
* [[FATTY-ACYL-COA-SYNTHASE-RXN]]
 +
* [[RXN-9951]]
 +
* [[RXN-701]]
 +
* [[ACETOLACTREDUCTOISOM-RXN]]
 +
* [[ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN]]
 +
* [[RXN1F-10]]
 +
* [[GLYCEROL-DEHYDROGENASE-NADP+-RXN]]
 +
* [[N-ACETYLGLUTPREDUCT-RXN]]
 +
* [[LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN]]
 +
* [[RXN-14209]]
 
== External links  ==
 
== External links  ==
−
* RHEA:
+
* CAS : 2646-71-1
−
** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=17453 17453]
+
* BIGG : 33486
−
* LIGAND-RXN:
+
* PUBCHEM:
−
** [http://www.genome.jp/dbget-bin/www_bget?R04144 R04144]
+
** [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=15983949 15983949]
−
* UNIPROT:
+
* HMDB : HMDB00221
−
** [http://www.uniprot.org/uniprot/P07244 P07244]
+
* LIGAND-CPD:
−
** [http://www.uniprot.org/uniprot/Q58347 Q58347]
+
** [http://www.genome.jp/dbget-bin/www_bget?C00005 C00005]
−
** [http://www.uniprot.org/uniprot/P12039 P12039]
+
* CHEMSPIDER:
−
** [http://www.uniprot.org/uniprot/P21872 P21872]
+
** [http://www.chemspider.com/Chemical-Structure.10239199.html 10239199]
−
** [http://www.uniprot.org/uniprot/P15640 P15640]
+
* CHEBI:
−
** [http://www.uniprot.org/uniprot/P00967 P00967]
+
** [http://www.ebi.ac.uk/chebi/searchId.do?chebiId=57783 57783]
−
** [http://www.uniprot.org/uniprot/P16340 P16340]
+
* METABOLIGHTS : MTBLC57783
−
** [http://www.uniprot.org/uniprot/P22102 P22102]
+
{{#set: smiles=C5(N(C1(OC(C(C1O)O)COP(OP(OCC4(C(C(C(N3(C2(=C(C(=NC=N2)N)N=C3)))O4)OP([O-])([O-])=O)O))([O-])=O)(=O)[O-]))C=C(CC=5)C(=O)N)}}
−
** [http://www.uniprot.org/uniprot/Q9JWU6 Q9JWU6]
+
{{#set: inchi key=InChIKey=ACFIXJIJDZMPPO-NNYOXOHSSA-J}}
−
** [http://www.uniprot.org/uniprot/P43845 P43845]
+
{{#set: common name=NADPH}}
−
** [http://www.uniprot.org/uniprot/Q9PN47 Q9PN47]
+
{{#set: molecular weight=741.394    }}
−
** [http://www.uniprot.org/uniprot/Q64737 Q64737]
+
{{#set: common name=reduced nicotinamide adenine dinucleotide phosphate|NADPH2|dihydrotriphosphopyridine nucleotide|reduced dihydrotriphosphopyridine nucleotide|dihydronicotinamide adenine dinucleotide phosphate|dihydronicotinamide adenine dinucleotide phosphate reduced|reduced NADP|NADP-red|TPNH|dihydronicotinamide adenine dinucleotide-P|β-NADPH}}
−
** [http://www.uniprot.org/uniprot/P20772 P20772]
+
{{#set: consumed by=RXN-7660|RXN1G-1053|RXN-4144|RXN-7665|RXN-16616|RXN66-323|RXN-711|RXN-16129|RXN-715|RXN1G-349|RXN-7664|RXN-600|1.14.13.70-RXN|RXN-7666|THIOREDOXIN-REDUCT-NADPH-RXN|RXN-13307|RXN-17678|RXN-4225|RXN-9546|RXN66-12|RXN-17109|RXN-7677|RXN-7676|UDPNACETYLMURAMATEDEHYDROG-RXN|1.2.1.13-RXN|RXN-7784|RXN0-2142|RXN-13398|RXN1G-358|RXN-16114|RXN-16112|RXN-3142|RXN-15046|RXN-10625|GLUTSEMIALDEHYDROG-RXN|RXN1G-260|RXN1G-508|RXN-17428|RXN-13707|RXN-9536|RXN-9532|RXN-14014|RXN-11881|RXN-17111|RXN-1106|RXN1G-364|RXN-1102|RXN-1101|RXN1G-287|RXN-5285|RXN-9633|RXN-9524|RXN-9528|RXN1A0-6303|RXN0-1281|RXN-16765|RXN-14790|NADPH-DEHYDROGENASE-FLAVIN-RXN|GLUTRNAREDUCT-RXN|RXN-14715|RXN-9540|RXN-9556|RXN-13724|RXN-9552|RXN-707|RXN-13431|KYNURENINE-3-MONOOXYGENASE-RXN|RXN-4210|RXN1G-881|RXN-1125|RXN-10060|GMP-REDUCT-RXN|RXN-1121|RXN1G-469|3-HYDROXYBUTYRYL-COA-DEHYDROGENASE-RXN|1.14.13.79-RXN|DIENOYLCOAREDUCT-RXN|DIHYDROFOLATEREDUCT-RXN|RXN-14973|RXN-14972|1.1.1.271-RXN|RXN66-27|GLUTAMATESYN-RXN|RXN-7659|RXN-7658|RIBOFLAVINSYNREDUC-RXN|RXN-12521|FLAVONADPREDUCT-RXN|RXN-10655|PYRNUTRANSHYDROGEN-RXN|RXN-10659|RXN1G-163|RXN-16097|RXN-16095|RXN-16622|1.14.13.8-RXN|2-DEHYDROPANTOATE-REDUCT-RXN|RXN-8853|RXN-14776|TRANSENOYLCOARED-RXN|RXN-13299|GLYOXYLATE-REDUCTASE-NADP+-RXN|RXN-16016|RXN3O-130|RXN66-13|RXN66-11|ACETOOHBUTREDUCTOISOM-RXN|RXN66-14|GLUTATHIONE-REDUCT-NADPH-RXN|RXN-15006|RXN-12747|RXN-7835|RXN-11476|RXN-13961|RXN1G-240|RXN-16630|RXN66-305|RXN66-304|RXN66-306|RXN-773|RXN66-303|DIHYDROFOLATEREDUCT-RXN-THF/NADP//DIHYDROFOLATE/NADPH/PROTON.37.|SHIKIMATE-5-DEHYDROGENASE-RXN|RXN-11480|NITRATE-REDUCTASE-NADPH-RXN|1.5.1.8-RXN|RXN66-482|3-OXOACYL-ACP-REDUCT-RXN|RXN1G-72|RXN66-81|RXN-9725|DIHYDROKAEMPFEROL-4-REDUCTASE-RXN|1.5.1.19-RXN|SULFITE-REDUCT-RXN|RXN-16131|RXN-16626|RXN1F-160|RXN1F-161|RXN-9518|RXN-4231|RXN-9514|RXN-9515}}
−
** [http://www.uniprot.org/uniprot/P26977 P26977]
+
{{#set: produced by=TRANS-RXN0-277|RXN-924|RXN-9952|MALIC-NADP-RXN|ALDEHYDE-DEHYDROGENASE-NADP+-RXN|RXN0-3962|1.18.1.2-RXN|RXN-5682|BENZALDEHYDE-DEHYDROGENASE-NADP+-RXN|GLU6PDEHYDROG-RXN}}
−
** [http://www.uniprot.org/uniprot/Q59492 Q59492]
+
{{#set: reversible reaction associated=ISOCITDEH-RXN|RXN-7911|RXN-1124|RXN1G-157|1.3.99.5-RXN|RXN-13008|GLUTDEHYD-RXN|METHYLENETHFDEHYDROG-NADP-RXN|RXN-8349_PLANTCYC|1.1.1.34-RXN|FATTY-ACID-SYNTHASE-RXN|DXPREDISOM-RXN|PREPHENATE-DEHYDROGENASE-NADP+-RXN|RXN-15115|FATTY-ACYL-COA-SYNTHASE-RXN|RXN-9951|RXN-701|ACETOLACTREDUCTOISOM-RXN|ASPARTATE-SEMIALDEHYDE-DEHYDROGENASE-RXN|RXN1F-10|GLYCEROL-DEHYDROGENASE-NADP+-RXN|N-ACETYLGLUTPREDUCT-RXN|LONG-CHAIN-FATTY-ACYL-COA-REDUCTASE-RXN|RXN-14209}}
−
** [http://www.uniprot.org/uniprot/P74232 P74232]
+
−
** [http://www.uniprot.org/uniprot/Q42804 Q42804]
+
−
** [http://www.uniprot.org/uniprot/P52421 P52421]
+
−
{{#set: direction=LEFT-TO-RIGHT}}
+
−
{{#set: common name=phosphoribosylamine-glycine ligase}}
+
−
{{#set: ec number=EC-6.3.4.13}}
+
−
{{#set: gene associated=Ec-12_005490}}
+
−
{{#set: in pathway=PWY-6121|PWY-6122|PWY-6277}}
+
−
{{#set: reconstruction category=orthology|annotation}}
+
−
{{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
+
−
{{#set: reconstruction tool=pantograph|pathwaytools}}
+

Latest revision as of 19:04, 21 March 2018

Metabolite NADPH

  • smiles:
    • C5(N(C1(OC(C(C1O)O)COP(OP(OCC4(C(C(C(N3(C2(=C(C(=NC=N2)N)N=C3)))O4)OP([O-])([O-])=O)O))([O-])=O)(=O)[O-]))C=C(CC=5)C(=O)N)
  • inchi key:
    • InChIKey=ACFIXJIJDZMPPO-NNYOXOHSSA-J
  • common name:
    • NADPH
  • molecular weight:
    • 741.394
  • Synonym(s):
    • reduced nicotinamide adenine dinucleotide phosphate
    • NADPH2
    • dihydrotriphosphopyridine nucleotide
    • reduced dihydrotriphosphopyridine nucleotide
    • dihydronicotinamide adenine dinucleotide phosphate
    • dihydronicotinamide adenine dinucleotide phosphate reduced
    • reduced NADP
    • NADP-red
    • TPNH
    • dihydronicotinamide adenine dinucleotide-P
    • β-NADPH

Reaction(s) known to consume the compound

Reaction(s) known to produce the compound

Reaction(s) of unknown directionality

External links

  • CAS : 2646-71-1
  • BIGG : 33486
  • PUBCHEM:
  • HMDB : HMDB00221
  • LIGAND-CPD:
  • CHEMSPIDER:
  • CHEBI:
  • METABOLIGHTS : MTBLC57783
"C5(N(C1(OC(C(C1O)O)COP(OP(OCC4(C(C(C(N3(C2(=C(C(=NC=N2)N)N=C3)))O4)OP([O-])([O-])=O)O))([O-])=O)(=O)[O-]))C=C(CC=5)C(=O)N)" cannot be used as a page name in this wiki.




Retrieved from "http://gem-aureme.irisa.fr/ectogem/index.php?title=NADPH&oldid=24363"