Difference between revisions of "HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN"

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(Created page with "Category:Metabolite == Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-18493 CPD-18493] == * smiles: ** CCCCCC=CCC=CCC=CCC=CCC=CCCC(O)CC(SCCNC(=O)CCNC(=O)C(O)C(C)...")
(Created page with "Category:Reaction == Reaction [http://metacyc.org/META/NEW-IMAGE?object=HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN] == * direction: ** R...")
 
(One intermediate revision by the same user not shown)
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[[Category:Metabolite]]
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[[Category:Reaction]]
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== Metabolite [http://metacyc.org/META/NEW-IMAGE?object=CPD-18493 CPD-18493] ==
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== Reaction [http://metacyc.org/META/NEW-IMAGE?object=HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN] ==
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* smiles:
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* direction:
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** CCCCCC=CCC=CCC=CCC=CCC=CCCC(O)CC(SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(=O)(OP(=O)(OCC1(C(OP([O-])(=O)[O-])C(O)C(O1)N3(C2(=C(C(N)=NC=N2)N=C3))))[O-])[O-])=O
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** REVERSIBLE
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* inchi key:
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** InChIKey=NNEPPYNERZEJEE-VUGYPBMHSA-J
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* common name:
 
* common name:
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** (3S)-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA
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** Thiolase-like, subgroup
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* molecular weight:
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** Hydroxymethylglutaryl-CoA synthase
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** 1120.05   
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* ec number:
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** [http://enzyme.expasy.org/EC/2.3.3.10 EC-2.3.3.10]
 
* Synonym(s):
 
* Synonym(s):
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** (3S)-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosa-6,9,12,15,18-pentaenoyl-CoA
 
  
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== Reaction(s) known to consume the compound ==
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== Reaction Formula ==
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* [[RXN-17115]]
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* With identifiers:
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== Reaction(s) known to produce the compound ==
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** 1 [[ACETYL-COA]][c] '''+''' 1 [[ACETOACETYL-COA]][c] '''+''' 1 [[WATER]][c] '''<=>''' 1 [[3-HYDROXY-3-METHYL-GLUTARYL-COA]][c] '''+''' 1 [[CO-A]][c] '''+''' 1 [[PROTON]][c]
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* [[RXN-17114]]
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* With common name(s):
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== Reaction(s) of unknown directionality ==
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** 1 acetyl-CoA[c] '''+''' 1 acetoacetyl-CoA[c] '''+''' 1 H2O[c] '''<=>''' 1 (S)-3-hydroxy-3-methylglutaryl-CoA[c] '''+''' 1 coenzyme A[c] '''+''' 1 H+[c]
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== Genes associated with this reaction  ==
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Genes have been associated with this reaction based on different elements listed below.
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* Gene: [[Ec-19_002030]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Assignment: EC-NUMBER
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* Gene: [[Ec-21_004360]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Assignment: EC-NUMBER
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** Source: [[orthology-aragem]]
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== Pathways  ==
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* [[PWY66-367]], ketogenesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY66-367 PWY66-367]
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** '''3''' reactions found over '''5''' reactions in the full pathway
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* [[PWY-6174]], mevalonate pathway II (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-6174 PWY-6174]
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** '''5''' reactions found over '''7''' reactions in the full pathway
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* [[PWY-922]], mevalonate pathway I: [http://metacyc.org/META/NEW-IMAGE?object=PWY-922 PWY-922]
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** '''7''' reactions found over '''7''' reactions in the full pathway
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* [[PWY-7391]], isoprene biosynthesis II (engineered): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7391 PWY-7391]
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** '''7''' reactions found over '''8''' reactions in the full pathway
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* [[PWY-7571]], ferrichrome A biosynthesis: [http://metacyc.org/META/NEW-IMAGE?object=PWY-7571 PWY-7571]
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** '''2''' reactions found over '''5''' reactions in the full pathway
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* [[PWY-7524]], mevalonate pathway III (archaea): [http://metacyc.org/META/NEW-IMAGE?object=PWY-7524 PWY-7524]
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** '''4''' reactions found over '''8''' reactions in the full pathway
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== Reconstruction information  ==
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* Category: [[orthology]]
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** Source: [[orthology-aragem]]
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*** Tool: [[pantograph]]
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* Category: [[annotation]]
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** Source: [[annotation-esiliculosus_genome]]
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*** Tool: [[pathwaytools]]
 
== External links  ==
 
== External links  ==
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{{#set: smiles=CCCCCC=CCC=CCC=CCC=CCC=CCCC(O)CC(SCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(=O)(OP(=O)(OCC1(C(OP([O-])(=O)[O-])C(O)C(O1)N3(C2(=C(C(N)=NC=N2)N=C3))))[O-])[O-])=O}}
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* RHEA:
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{{#set: inchi key=InChIKey=NNEPPYNERZEJEE-VUGYPBMHSA-J}}
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** [http://www.ebi.ac.uk/rhea/reaction.xhtml?id=10188 10188]
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{{#set: common name=(3S)-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA}}
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* LIGAND-RXN:
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{{#set: molecular weight=1120.05    }}
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** [http://www.genome.jp/dbget-bin/www_bget?R01978 R01978]
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{{#set: common name=(3S)-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosa-6,9,12,15,18-pentaenoyl-CoA}}
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* UNIPROT:
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{{#set: consumed by=RXN-17115}}
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** [http://www.uniprot.org/uniprot/P13704 P13704]
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{{#set: produced by=RXN-17114}}
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** [http://www.uniprot.org/uniprot/P22791 P22791]
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** [http://www.uniprot.org/uniprot/P54870 P54870]
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** [http://www.uniprot.org/uniprot/P54869 P54869]
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** [http://www.uniprot.org/uniprot/O51626 O51626]
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** [http://www.uniprot.org/uniprot/Q9CFA9 Q9CFA9]
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** [http://www.uniprot.org/uniprot/P17425 P17425]
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** [http://www.uniprot.org/uniprot/Q7LZE7 Q7LZE7]
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** [http://www.uniprot.org/uniprot/Q01581 Q01581]
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** [http://www.uniprot.org/uniprot/P54961 P54961]
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** [http://www.uniprot.org/uniprot/P54839 P54839]
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** [http://www.uniprot.org/uniprot/P54874 P54874]
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** [http://www.uniprot.org/uniprot/P54868 P54868]
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** [http://www.uniprot.org/uniprot/P54873 P54873]
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** [http://www.uniprot.org/uniprot/P93773 P93773]
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{{#set: direction=REVERSIBLE}}
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{{#set: common name=Thiolase-like, subgroup}}
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{{#set: common name=Hydroxymethylglutaryl-CoA synthase}}
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{{#set: ec number=EC-2.3.3.10}}
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{{#set: gene associated=Ec-19_002030|Ec-21_004360}}
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{{#set: in pathway=PWY66-367|PWY-6174|PWY-922|PWY-7391|PWY-7571|PWY-7524}}
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{{#set: reconstruction category=orthology|annotation}}
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{{#set: reconstruction source=annotation-esiliculosus_genome|orthology-aragem}}
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{{#set: reconstruction tool=pantograph|pathwaytools}}

Latest revision as of 19:11, 21 March 2018

Reaction HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN

  • direction:
    • REVERSIBLE
  • common name:
    • Thiolase-like, subgroup
    • Hydroxymethylglutaryl-CoA synthase
  • ec number:
  • Synonym(s):

Reaction Formula

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

Pathways

  • PWY66-367, ketogenesis: PWY66-367
    • 3 reactions found over 5 reactions in the full pathway
  • PWY-6174, mevalonate pathway II (archaea): PWY-6174
    • 5 reactions found over 7 reactions in the full pathway
  • PWY-922, mevalonate pathway I: PWY-922
    • 7 reactions found over 7 reactions in the full pathway
  • PWY-7391, isoprene biosynthesis II (engineered): PWY-7391
    • 7 reactions found over 8 reactions in the full pathway
  • PWY-7571, ferrichrome A biosynthesis: PWY-7571
    • 2 reactions found over 5 reactions in the full pathway
  • PWY-7524, mevalonate pathway III (archaea): PWY-7524
    • 4 reactions found over 8 reactions in the full pathway

Reconstruction information

External links





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