2.7.1.127-RXN

Reaction 2.7.1.127-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • ORF
  • inositol_-trisphosphate_3-kinase
• ec number:
  • EC-2.7.1.127
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 INOSITOL-1-4-5-TRISPHOSPHATE[c] + 1 ATP[c] => 1 PROTON[c] + 1 ADP[c] + 1 CPD-506[c]
• With common name(s):
  • 1 D-myo-inositol (1,4,5)-trisphosphate[c] + 1 ATP[c] => 1 H+[c] + 1 ADP[c] + 1 D-myo-inositol (1,3,4,5)-tetrakisphosphate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_8121
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-esiliculosus
• Gene: Tiso_gene_15143
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_15142
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER

Pathways

• PWY-6364, D-myo-inositol (1,3,4)-trisphosphate biosynthesis: PWY-6364
  • 3 reactions found over 3 reactions in the full pathway
• PWY-6362, 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian): PWY-6362
  • 5 reactions found over 5 reactions in the full pathway
• PWY-6361, 1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3): PWY-6361
  • 2 reactions found over 5 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 11020
• LIGAND-RXN:
  • R03433
• UNIPROT:
  • P23677
  • P17105
  • P42335
  • O45049
  • O45050
  • O45051