3-HYDROXY-KYNURENINASE-RXN

Reaction 3-HYDROXY-KYNURENINASE-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • kynureninase
• ec number:
  • EC-3.7.1.3
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 WATER[c] + 1 3-HYDROXY-L-KYNURENINE[c] => 1 3-HYDROXY-ANTHRANILATE[c] + 1 L-ALPHA-ALANINE[c] + 1 PROTON[c]
• With common name(s):
  • 1 H2O[c] + 1 3-hydroxy-L-kynurenine[c] => 1 3-hydroxyanthranilate[c] + 1 L-alanine[c] + 1 H+[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_10685
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_10684
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER

Pathways

• PWY-5651, L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde: PWY-5651
  • 4 reactions found over 5 reactions in the full pathway
• PWY-6309, L-tryptophan degradation XI (mammalian, via kynurenine): PWY-6309
  • 9 reactions found over 17 reactions in the full pathway

Reconstruction information

• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 25143
• LIGAND-RXN:
  • R02668