ISOCIT-CLEAV-RXN

Reaction ISOCIT-CLEAV-RXN

• direction:
  • REVERSIBLE
• common name:
  • isocitrate_lyase
• ec number:
  • EC-4.1.3.1
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 THREO-DS-ISO-CITRATE[c] <=> 1 GLYOX[c] + 1 SUC[c]
• With common name(s):
  • 1 D-threo-isocitrate[c] <=> 1 glyoxylate[c] + 1 succinate[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_14008
  • Source: annotation-in-silico_annotation
    • Assignment: AUTOMATED-NAME-MATCH
  • Source: annotation-experimental_annotation
    • Assignment: AUTOMATED-NAME-MATCH
  • Source: orthology-esiliculosus

Pathways

• P105-PWY, TCA cycle IV (2-oxoglutarate decarboxylase): P105-PWY
  • 9 reactions found over 11 reactions in the full pathway
• GLYOXYLATE-BYPASS, glyoxylate cycle: GLYOXYLATE-BYPASS
  • 6 reactions found over 6 reactions in the full pathway
• PWY-6969, TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase): PWY-6969
  • 9 reactions found over 12 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 13245
• PIR:
  • A41338
  • I40713
  • JA0155
  • JC6182
  • S26857
  • S26858
  • S39953
  • S52819
  • S77654
  • T04115
  • T06353
  • T07631
  • T07632
  • T08046
  • T09774
  • T09779
  • T11209
  • WZBYI
  • WZCKI
  • WZCNIU
  • WZCSI
  • WZECIC
  • WZRPI
• LIGAND-RXN:
  • R00479
• UNIPROT:
  • P28467
  • P42449
  • P20699
  • O13439
  • P28299
  • Q12031
  • P46831
  • O24588
  • P49297
  • P45456
  • P45457
  • Q39577
  • Q41084
  • Q43097
  • P28240
  • P20014
  • P17069
  • P15479
  • P0A9G6
  • P25248