RXN-12693

Reaction RXN-12693

• direction:
  • LEFT-TO-RIGHT
• common name:
  • 3-beta_hydroxysteroid_dehydrogenase_isomerase
  • ORF
• ec number:
  • EC-1.1.1.145
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 NAD[c] + 1 CHOLESTEROL[c] => 1 PROTON[c] + 1 NADH[c] + 1 CPD-13684[c]
• With common name(s):
  • 1 NAD+[c] + 1 cholesterol[c] => 1 H+[c] + 1 NADH[c] + 1 cholest-5-en-3-one[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_11016
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_2957
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_18774
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
• Gene: Tiso_gene_897
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-esiliculosus

Pathways

• PWY-6946, cholesterol degradation to androstenedione II (cholesterol dehydrogenase): PWY-6946
  • 3 reactions found over 22 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools