RXN-7719

Reaction RXN-7719

• direction:
  • REVERSIBLE
• common name:
  • 3-methyl-2-oxobutanoate_dehydrogenase
• ec number:
  • EC-1.8.1.4
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 BCAA-dehydrogenase-DH-lipoyl[c] + 1 NAD[c] <=> 1 BCAA-dehydrogenase-lipoyl[c] + 1 PROTON[c] + 1 NADH[c]
• With common name(s):
  • 1 an [apo BCAA dehydrogenase E2 protein] N6-dihydrolipoyl-L-lysine[c] + 1 NAD+[c] <=> 1 an [apo BCAA dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] + 1 H+[c] + 1 NADH[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_3260
  • Source: annotation-experimental_annotation
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: Tiso_gene_11793
  • Source: annotation-in-silico_annotation
    • Assignment: AUTOMATED-NAME-MATCH
• Gene: Tiso_gene_9330
  • Source: orthology-esiliculosus

Pathways

• PWY-5046, 2-oxoisovalerate decarboxylation to isobutanoyl-CoA: PWY-5046
  • 3 reactions found over 3 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: annotation
  • Source: annotation-experimental_annotation
    • Tool: pathwaytools
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools