RXN0-1134
From metabolic_network
Contents
Reaction RXN0-1134
- direction:
- LEFT-TO-RIGHT
- common name:
- pyruvate_dehydrogenase_e1_component_subunit_alpha-_mitochondrial
- dihydrolipoamide_acetyltransferase
- ORF
- ec number:
- Synonym(s):
Reaction Formula
- With identifiers:
- 1 PROTON[c] + 1 PYRUVATE[c] + 1 Pyruvate-dehydrogenase-lipoate[c] => 1 CARBON-DIOXIDE[c] + 1 Pyruvate-dehydrogenase-acetylDHlipoyl[c]
- With common name(s):
- 1 H+[c] + 1 pyruvate[c] + 1 a [pyruvate dehydrogenase E2 protein] N6-lipoyl-L-lysine[c] => 1 CO2[c] + 1 a [pyruvate dehydrogenase E2 protein] N6-S-acetyldihydrolipoyl-L-lysine[c]
Genes associated with this reaction
Genes have been associated with this reaction based on different elements listed below.
- Gene: Tiso_gene_2693
- Source: annotation-in-silico_annotation
- Assignment: EC-NUMBER
- Source: annotation-experimental_annotation
- Assignment: EC-NUMBER
- Source: annotation-in-silico_annotation
- Gene: Tiso_gene_7519
- Source: annotation-in-silico_annotation
- Assignment: EC-NUMBER
- Source: orthology-esiliculosus
- Source: annotation-in-silico_annotation
- Gene: Tiso_gene_6983
- Source: annotation-in-silico_annotation
- Assignment: EC-NUMBER
- Source: annotation-experimental_annotation
- Assignment: EC-NUMBER
- Source: annotation-in-silico_annotation
- Gene: Tiso_gene_17539
- Source: annotation-experimental_annotation
- Assignment: EC-NUMBER
- Source: orthology-esiliculosus
- Source: annotation-experimental_annotation
- Gene: Tiso_gene_2515
- Source: annotation-experimental_annotation
- Assignment: EC-NUMBER
- Source: orthology-esiliculosus
- Source: annotation-experimental_annotation
Pathways
- PYRUVDEHYD-PWY, pyruvate decarboxylation to acetyl CoA: PYRUVDEHYD-PWY
- 3 reactions found over 3 reactions in the full pathway
Reconstruction information
- Category: orthology
- Source: orthology-esiliculosus
- Tool: pantograph
- Source: orthology-esiliculosus
- Category: manual
- Source: manual-primary_network
- Category: annotation
- Source: annotation-in-silico_annotation
- Tool: pathwaytools
- Source: annotation-experimental_annotation
- Tool: pathwaytools
- Source: annotation-in-silico_annotation
External links
- LIGAND-RXN:
- UNIPROT:
- P06959
- P26267
- P35485
- Q59097
- Q9N1X8
- P45119
- P11966
- P35488
- P47515
- P21882
- P47516
- P21881
- P21873
- P16387
- P0AFG8
- P08559
- P11177
- P29803
- P29804
- P26284
- Q9JU08
- Q9CJD6
- Q9JU07
- Q9CJD5
- Q09171
- P52901
- P79931
- P79932
- Q9D051
- P10801
- P21874
- P49432
- Q59820
- P35486
- P35487
- Q06437
- P32473
- Q59107
- P73405
- Q49109
- O48685
- P52902
- P52904
- P52903
- O66112
- Q9Y8I5
- Q9Y8I6
- O69478
- P10802
