UROGENIIISYN-RXN

Reaction UROGENIIISYN-RXN

• direction:
  • LEFT-TO-RIGHT
• common name:
  • ORF
  • uroporphyrinogen_synthase
• ec number:
  • EC-4.2.1.75
• Synonym(s):

Reaction Formula

• With identifiers:
  • 1 HYDROXYMETHYLBILANE[c] => 1 UROPORPHYRINOGEN-III[c] + 1 WATER[c]
• With common name(s):
  • 1 preuroporphyrinogen[c] => 1 uroporphyrinogen-III[c] + 1 H2O[c]

Genes associated with this reaction

Genes have been associated with this reaction based on different elements listed below.

• Gene: Tiso_gene_11630
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER
  • Source: orthology-esiliculosus
  • Source: orthology-creinhardtii
• Gene: Tiso_gene_18827
  • Source: annotation-in-silico_annotation
    • Assignment: EC-NUMBER

Pathways

• PWY-5189, tetrapyrrole biosynthesis II (from glycine): PWY-5189
  • 3 reactions found over 4 reactions in the full pathway
• PWY-5188, tetrapyrrole biosynthesis I (from glutamate): PWY-5188
  • 6 reactions found over 6 reactions in the full pathway

Reconstruction information

• Category: orthology
  • Source: orthology-creinhardtii
    • Tool: pantograph
  • Source: orthology-esiliculosus
    • Tool: pantograph
• Category: manual
  • Source: manual-primary_network
• Category: annotation
  • Source: annotation-in-silico_annotation
    • Tool: pathwaytools

External links

• RHEA:
  • 18965
• LIGAND-RXN:
  • R03165
• UNIPROT:
  • P10746
  • P51163
  • P21248
  • Q58401
  • P09126
  • Q59294